The no-effect dose of 3 mg/kg/day is approximately equal to the MRHD on a mg/m 2 basis. Pregnancy: Based on animal data, may cause fetal harm ( 8.1 ) 8.1 Pregnancy Risk Summary There are no adequate data on the developmental risks associated with the use of ARICEPT in pregnant women. J Clin Psychiatry 62 (2001): 573-4, 11. However, it can improve thinking ability in some patients. This drug may make you dizzy or drowsy. Other dosage forms: Along with its needed effects, donepezil (the active ingredient contained in Aricept) may cause some unwanted effects. While waiting for new doctor to take over past neurologist's care, have adjusted meds myself to keep the memory help - which is astounding - and lessens side effects which includes severe muscle cramps in legs, water retention, ankle and hand swelling, back pain, increased blood pressure, heart palpitations. Last updated on May 14, 2023. O 0, 4. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Liver function: Liver disease or reduced liver function may cause this medication to build up in the body, causing side effects. The amount of medicine that you take depends on the strength of the medicine. Vision changes are also possible. Mayo Clinic does not endorse any of the third party products and services advertised. Inactive ingredients are carrageenan, mannitol, colloidal silicon dioxide, and polyvinyl alcohol. Most Common Adverse Reactions Leading to Discontinuation in Patients with Mild to Moderate Alzheimers Disease Adverse Reaction Placebo (n=355) % 5 mg/day ARICEPT (n=350) % 10 mg/day ARICEPT (n=315) % Nausea 1 1 3 Diarrhea 0 <1 3 Vomiting <1 <1 2 Most Common Adverse Reactions The most common adverse reactions, defined as those occurring at a frequency of at least 5% in patients receiving 10 mg/day and twice the placebo rate, are largely predicted by ARICEPTs cholinomimetic effects. It can be harmful for people to take this medication if their doctor has not prescribed it. However, the dose usually is not more than 23 mg per day. Each ARICEPT ODT tablet contains 5 or 10 mg of donepezil hydrochloride. The range of prescription discounts provided under this discount plan will vary depending on the prescription and pharmacy where the prescription is purchased and can be up to 80% off the cash price. Swelling of the throat, lips, or face. It has an empirical formula of C 24 H 29 NO 3 HCl and a molecular weight of 415.96. In this study, there were no important differences in the type of adverse reactions in patients taking ARICEPT with or without memantine. The safety and effectiveness in pediatric patients have not been established. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. People with cardiac conduction abnormalities (e.g., heart rhythm problems such as sick sinus syndrome) should not take donepezil. However, it can improve thinking ability in some patients. The package insert recommends that donepezil be administered in the evening just before retiring. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Donepezil may also be used for other purposes not listed in this medication guide. www.medbroadcast.com/drug/getdrug/Aricept, are allergic to donepezil or any ingredients of the medication, are allergic to piperidine-type medications (e.g., rifabutin, methylphenidate, bupivacaine, paroxetine), mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness, signs of muscle damage (e.g., muscle pain, tenderness or weakness, or brown or discoloured urine), especially if you also have a fever or a general feeling of being unwell, signs of bleeding in the stomach (e.g., bloody, black, or tarry stools, spitting up of blood, vomiting blood or material that looks like coffee grounds), symptoms of neuroleptic malignant syndrome (e.g., muscle pain, tenderness or weakness, or joint pain accompanied by a fever or very dark urine), antihistamines (e.g., cetirizine, doxylamine, diphenhydramine, hydroxyzine, loratadine), antipsychotics (e.g., chlorpromazine, clozapine, haloperidol, olanzapine, quetiapine, risperidone), barbiturates (e.g., phenobarbital), beta-adrenergic blockers (e.g., atenolol, propranolol, sotalol), corticosteroids (e.g., budesonide, dexamethasone, hydrocortisone, fluticasone, prednisone), tricyclic antidepressants (e.g., amitriptyline, clomipramine, desipramine, trimipramine). Additionally, the 10 mg tablet contains yellow iron oxide (synthetic) as a coloring agent. Comparison of Rates of Adverse Reactions in Mild to M oderate Patients Titrated to 10 mg/day over 1 and 6 Weeks No titration One week titration Six week titration Adverse Reaction Placebo (n=315) % 5 mg/day (n=311) % 10 mg/day (n=315) % 10 mg/day (n=269) % Nausea 6 5 19 6 Diarrhea 5 8 15 9 Insomnia 6 6 14 6 Fatigue 3 4 8 3 Vomiting 3 3 8 5 Muscle cramps 2 6 8 3 Anorexia 2 3 7 3 Table 3 lists adverse reactions that occurred in at least 2% of patients in pooled placebo-controlled trials who received either ARICEPT 5 mg or 10 mg and for which the rate of occurrence was greater for patients treated with ARICEPT than with placebo. Follow your doctor's orders or the directions on the label. Applies to donepezil: oral tablet, oral tablet disintegrating. We comply with the HONcode standard for trustworthy health information. The strength, in mg (23), is debossed on one side, and ARICEPT is debossed on the other side. Talk to your doctor if you are using marijuana (cannabis). It contains the active drug donepezil. Breast-feeding: It is not known if donepezil passes into breast milk. Frequency of common adverse effects may be influenced by the rate of titration. It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to function. This is not a complete list of side effects and others may occur. In animal studies, developmental toxicity was not observed when donepezil was administered to pregnant rats and rabbits during organogenesis, but administration to rats during the latter part of pregnancy and throughout lactation resulted in increased stillbirths and decreased offspring survival at clinically relevant doses [ see Data ]. ARICEPT has been administered to over 1,700 individuals during clinical trials worldwide. Iraqi A, Hughes TL "An unusual case of nightmares with galantamine." You may need to start at a lower dose to decrease the risk of side effects. Consult your doctor or pharmacist for more details. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Heart problemsDonepezil may have unwanted effects on heart rate. Your reactions could be impaired. To reduce your risk of side effects (such as nausea and diarrhea ), your doctor will start this medication at a low dose and gradually increase your dose over weeks to months. By subscribing you agree to the Terms of Use and Privacy Policy. Drug information provided by: Merative, Micromedex. Donepezil will not cure Alzheimer's disease, and it will not stop the disease from getting worse. The tablet should be swallowed whole with water. 1. Store at room temperature away from moisture and heat. Do not take other medicines unless they have been discussed with your doctor. efficacy of both drugs (hepatic metab. Aricept is also known as Donepezil hydrochloride, Eranz and E 2020. Keep from freezing. These include nausea, diarrhea, insomnia, vomiting, muscle cramp, fatigue, and anorexia. The range of patient exposure was from 1 to over 500 days. Talk to your pharmacist for more details. Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above). It may be taken with or without food, on a full or empty stomach. A side effect is an unwanted response to a medication when it is taken in normal doses. Donepezil may cause a condition that affects the heart rhythm (QT prolongation). Donepezil is used to treat dementia (memory loss and mental changes) associated with mild, moderate, or severe Alzheimer's disease. Common side effects of Aricept include: diarrhea, insomnia, and nausea. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. The most common adverse reactions leading to discontinuation, defined as those occurring in at least 2% of patients and at twice or more the incidence seen in placebo patients, are shown in Table 1. Other side effects not listed may also occur in some patients. Other side effects include: fatigue, muscle cramps, vomiting, weight loss, anorexia, and ecchymoses. This can result in permanent damage if left untreated. For moderate to severe Alzheimer's disease: Adults10 milligrams (mg) taken at bedtime. Data Animal Data Oral administration of donepezil to pregnant rats and rabbits during the period of organogenesis did not produce any teratogenic effects at doses up to 16 mg/kg/day (approximately 6 times the maximum recommended human dose [MRHD] of 23 mg/day on a mg/m 2 basis) and 10 mg/kg/day (approximately 7 times the MRHD on a mg/m 2 basis), respectively. Taking donepezil together with certain medicines that are used during surgery or dental or emergency treatments may increase the effects of those medicines and cause unwanted effects. The benefits of taking the medication must be carefully weighed against the risks. Immediately place the tablet on top of the tongue. Copyright 2023 Healthgrades Marketplace, LLC, Patent US Nos. Donepezil should be taken at bedtime unless otherwise directed by your doctor. Other side effects include: fatigue, muscle cramps, vomiting, weight loss, anorexia, and ecchymoses. Side effects Interactions What is Aricept? Email. Each white, film-coated tablet, marked "ARICEPT" on one side and "5" on the other, contains donepezil 5mg. Nonmedicinal ingredients: cornstarch, hydroxypropyl cellulose, lactose monohydrate, magnesium stearate, and microcrystalline cellulose; film coating: hydroxypropyl methylcellulose, polyethylene glycol, talc, and titanium dioxide. This condition will progress over time, even in people who take donepezil. In clinical trials, the most common adverse effects included nausea, diarrhea, insomnia, vomiting, muscle cramps, fatigue, and . Do not swallow the tablet whole. In animal studies, developmental toxicity was not observed when donepezil was administered to pregnant rats and rabbits during organogenesis, but administration to rats during the latter part of pregnancy and throughout lactation resulted in increased stillbirths and decreased offspring survival at clinically relevant doses [ see Data ]. This medicine may cause some people to become dizzy or drowsy, to have blurred vision, or to have problems with clumsiness or unsteadiness. Donepezil belongs to the class of medications called cholinesterase inhibitors. However, it was also ranked as the drug with the most side effects, like vomiting and nausea. This document does not contain all possible drug interactions. Consult your doctor before taking Aricept if pregnant or breastfeeding. thioridazine. UseDonepezil (Aricept)exactly as directed on the label, or as prescribed by your doctor. Heart disease: If you have heart disease such as active coronary artery disease or congestive heart failure, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Oral administration of donepezil (1, 3, 10 mg/kg/day) to rats during late gestation and throughout lactation to weaning produced an increase in stillbirths and reduced offspring survival through postpartum day 4 at the highest dose. Does Aricept interact with other drugs you are taking? mild to moderate Alzheimer's type dementia, moderate to severe Alzheimer's type dementia. If you notice the symptoms of NMS, get immediate medical attention. donepezil, memantine, Namenda, rivastigmine, galantamine, Exelon. Tell you doctor right away if you have bloody or black tarry stools, constipation, severe stomach pain, or vomiting of blood or material that looks like coffee grounds. If you do not take donepezil for 7 or more days in row, talk with your doctor before starting again. down the sink or in the toilet) or in household garbage. 8.6 Lower Weight Individuals In the controlled clinical trial, among patients in the ARICEPT 23 mg treatment group, those patients weighing < 55 kg reported more nausea, vomiting, and decreased weight than patients weighing 55 kg or more. These include diarrhea, anorexia, vomiting, nausea, and ecchymosis. ARICEPT contains the active substance donepezil hydrochloride. Submission of this form is subject to Healthgrades, Help Millions of people find the right doctor and care they need, Get immediate care and visit with providers from the comfort of your home, or anywhere, Urgent care centers can be faster and cheaper for situations that are not life threatening, Doctors and patients discuss the latest medical treatments and health tips, Search prescription drugs for why theyre used, side effects and more, Back and Neck Surgery (Except Spinal Fusion). Avoid driving or hazardous activity until you know how this medicine will affect you. The side effects listed below are not experienced by everyone who takes this medication. 1996-2023 Everyday Health, Inc., a Ziff Davis company. Donepezil most commonly causes stomach-related side effects, such as nausea, diarrhea, and appetite changes. However, the dose usually is not more than 10 mg per day. These adverse reactions were often transient, resolving during continued ARICEPT treatment without the need for dose modification. Cerner Multum, Inc. "UK Summary of Product Characteristics." Overdose Expiration Questions for your doctor About Aricept Aricept is a brand-name prescription medication. Most Common Adverse Reactions The most common adverse reactions, defined as those occurring at a frequency of at least 5% in patients receiving ARICEPT and at twice or more the placebo rate, are largely predicted by ARICEPTs cholinomimetic effects. If you have a history of seizure disorder, speak to your doctor about the risks and benefits of taking donepezil. Source: www.medbroadcast.com/drug/getdrug/Aricept, 02269465 Aricept RDT 10mg Tablet (rapidly-disintegrating). It is important that your doctor check your progress at regular visits. Although not all of these side effects may occur, if they do occur they may need medical attention. See Table 2 for a comparison of the most common adverse reactions following one and six week titration regimens. Our servers have detected that you are accessing this site from a restricted area. Medications other than those listed above may interact with this medication. Adverse Reactions in a Controlled Clinical Trial in Moderate to Severe Alzheimers Disease Adverse Reaction 23 mg/day ARICEPT (n=963) % 10 mg/day ARICEPT (n=471) % Percent of Patie nts with any Adverse Reaction 74 64 Nausea 12 3 Vomiting 9 3 Diarrhea 8 5 Anorexia 5 2 Dizziness 5 3 Weight Loss 5 3 Headache 4 3 Insomnia 3 2 Urinary Incontinence 3 1 Asthenia 2 1 Contusion 2 0 Fatigue 2 1 Somnolence 2 1 6.2 Postmarketing Experience The following adverse reactions have been identified during post-approval use of ARICEPT. Shortness of breath. Wheezing. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Signs of overdose include increased watering of mouth, increased sweating, low blood pressure, muscle weakness, severe nausea, severe vomiting, slow heartbeat, and troubled breathing. But it can also cause trouble sleeping, headaches, and muscle cramps. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Adverse Reactions Leading to Discontinuation The rates of discontinuation from controlled clinical trials of ARICEPT due to adverse reactions for the ARICEPT patients were approximately 12% compared to 7% for placebo patients. Things to remember when you fill your prescription. Aricept (donepezil)." This is a prescription discount plan. Aricept is a Cholinomimetics - ACHE Inhibitors. Anaphylaxis is a rare but life-threatening allergic reaction. If you have any questions, ask your doctor or pharmacist. Many of these side effects can be managed, and some may go away on their own over time. [Ref], Very common (10% or more): Diarrhea, nausea, Common (1% to 10%): Vomiting, abdominal disturbance, tooth ache, fecal incontinence, gastrointestinal bleeding, bloating, epigastric pain, Uncommon (0.1% to 1%): Gastrointestinal hemorrhage, gastric and duodenal ulcers, eructation, gingivitis, flatulence, periodontal abscess, cholelithiasis, drooling, dry mouth, fever sore, gastritis, irritable colon, tongue edema, epigastric distress, gastroenteritis, increased transaminases, hemorrhoids, ileus, increased thirst, jaundice, melena, polydipsia, duodenal ulcer, stomach ulcer, hernia hiatal[Ref], Common (1% to 10%): Dizziness, insomnia, somnolence, tremor, paresthesia, ataxia, nervousness, aphasia, Uncommon (0.1% to 1%): Seizure, bad taste, cerebrovascular accident, intracranial hemorrhage, transient ischemic attack, neuralgia, muscle spasm, dysphoria, gait abnormality, hypertonia, hypokinesia, neurodermatitis, numbness (localized), dysarthria, dysphasia, nystagmus, pacing, Rare (less than 0.1%): Extrapyramidal symptoms, Very rare (less than 0.01%): Neuroleptic malignant syndrome[Ref], Common (1% to 10%): Hypertension, hemorrhage, syncope, vasodilation, atrial fibrillation, hot flashes, hypotension. Do not take more of it or less of it, and do not take it more or less often than your doctor ordered. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. The tour begins on Aug. 3 in Sterling . Table 4. Submission of this form is subject to Healthgrades, Help Millions of people find the right doctor and care they need, Get immediate care and visit with providers from the comfort of your home, or anywhere, Urgent care centers can be faster and cheaper for situations that are not life threatening, Doctors and patients discuss the latest medical treatments and health tips, Search prescription drugs for why theyre used, side effects and more, Back and Neck Surgery (Except Spinal Fusion). confusion, disorientation, appetite loss, weight loss, daytime somnolence, vestibular dysfunction (loss of hearing and balance), daily nightmares, general malaise/sense of not feeling well, could not recognize family members, spikes in blood pressure. If you miss a dose, take it as soon as possible and continue with your regular schedule. Check with your doctor as soon as possible if any of the following side effects occur: Stop taking the medication and seek immediate medical attention if any of the following occur: Some people may experience side effects other than those listed. It is important that this medication be taken on a regular schedule as prescribed by your doctor. nor a Medicare prescription drug plan. The rate of discontinuation of patients who received 7-day escalations from 5 mg/day to 10 mg/day was higher at 13%. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. There is evidence to suggest that the frequency of these common adverse reactions may be affected by the rate of titration. You may report them to the FDA. Adverse Reactions Leading to Discontinuation The rate of discontinuation from a controlled clinical trial of ARICEPT 23 mg/day due to adverse reactions was higher (19%) than for the 10 mg/day treatment group (8%). 4 Nighttime administration was suggested to prevent the patient from experiencing the side effects during the day. These may be symptoms of stomach or bowel bleeding. inhibited, additive effects; antagonistic effects) thioridazine. Taking an overdose of this medicine may cause convulsions (seizures) or serious effects on your heart and your breathing. Tell your doctor if your condition worsens. For additional information, including an up-to-date list of pharmacies, or assistance with any problems related to this prescription drug discount plan, please contact customer service toll free at 844-234-3057, 24 hours a day, 7 days a week (except major holidays). Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. Ann Pharmacother 34 (2000): 1347, 10. Ask your prescriber if you experience any of the serious Aricept adverse events listed above. Sleep Deprivation and Memory Loss: Whats the Connection? It is approved to treat Alzheimer's disease, dementia with Lewy bodies, Down syndrome and Parkinson's disease. This medicine is available only with your doctor's prescription. You should not stop using donepezil without your doctor's advice. The presence of other medical problems may affect the use of this medicine. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Donepezil could cause symptoms of these conditions to worsen. It's taken once a day as a pill . How to store ARICEPT 6. Take your next dose at the regular time. Terms and conditions of use. You may report side effects to the FDA at 1-800-FDA-1088. Contraindicated. The range of patient exposure is from 1 to 1,214 days. All rights reserved. Viagra is used to treat erectile dysfunction (impotence) in men. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. During pregnancy, this medication should be used only when clearly needed. If you think that you or someone else may have taken an overdose of this medicine, get emergency help at once. Tell your doctor or dentist that you're taking this drug before you have any medical or dental surgeries or procedures. COMMON side effects If experienced, these tend to have a Severe expression i diarrhea If experienced, these tend to have a Less Severe expression i cramps difficulty sleeping nausea vomiting. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. You may take donepezil with or without food. Mihara M, Ohnishi A, Tomono Y, Hasegawa J, Shimamura Y, Yamazaki K, Morishita N "Pharmacokinetics of E2020, a new compound for Alzheimer's disease, in healthy male volunteers." signs of muscle damage (e.g., muscle pain, tenderness or weakness, or brown or discoloured urine), especially if you also have a fever or a general feeling of being unwell. Take this medication by mouth with or without food as directed by your doctor, usually once daily just before bedtime. Do not give this medication to anyone else, even if they have the same symptoms as you do. In general, adverse reactions occurred more frequently in female patients and with advancing age. The rapidly disintegrating tablet should be placed on the tongue and allowed to dissolve before swallowing with water. J Neurol Neurosurg Psychiat 66 (1999): 410, 9. In Canada - Call your doctor for medical advice about side effects. Check with your doctor as soon as possible if any of the following side effects occur: Other side effects not listed may also occur in some patients. ARICEPT ODT is supplied as round tablets containing either 5 mg or 10 mg of donepezil hydrochloride. Table 6 lists adverse reactions that occurred in at least 2% of patients who received 23 mg/day of ARICEPT and at a higher frequency than those receiving 10 mg/day of ARICEPT in a controlled clinical trial that compared the two doses. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. If you notice other effects not listed above, contact your doctor or pharmacist. 10 mg. 12/8/2016. All Rights Reserved. Side effects can be mild or severe, temporary or permanent. Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, chronic obstructive pulmonary disease), fainting, seizures, stomach/intestinal disease (such as ulcers, bleeding), trouble urinating (such as enlarged prostate). To help you remember, take it at the same time each day. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Miyaoka T, Seno H, Yamamori C, Inagaki T, Itoga M, Tsubouchi K, Horiguchi J "Pisa syndrome due to a cholinesterase inhibitor (Donepezil): A case report." The information within all other sections is proprietary to Everyday Health. Table 2. Side effects Interactions Dosage FAQ What is Viagra? How does this medication work? Aricept (donepezil) +. Tell your doctor right away if you have any serious side effects, including: trouble urinating, severe stomach/abdominal pain, black stools, vomit that looks like coffee grounds, seizures. mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, pains in stomach, side, or abdomen, possibly radiating to the back, seeing, hearing, or feeling things that are not there. Table 3. Do not keep outdated medicine or medicine no longer needed. ARICEPT (donepezil hydrochloride) is a reversible inhibitor of the enzyme acetylcholinesterase, known chemically as ()-2, 3-dihydro-5, 6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1 H -inden-1-one hydrochloride. Controlled and uncontrolled trials in the United States included approximately 900 patients. Consult your pharmacist or local waste disposal company. Nonmedicinal ingredients: lactose monohydrate, corn starch, microcrystalline cellulose, hydroxypropyl cellulose, and magnesium stearate; film coating: talc, polyethylene glycol, hypromellose, and titanium dioxide. Any of the medicines you are taking prolongation ( see above ) just retiring. And Aricept is debossed on aricept side effects viagra soft label, or severe Alzheimer 's type dementia, or.. And muscle cramps, vomiting, muscle cramp, fatigue, and.. Dysfunction ( impotence ) in men avoid driving or hazardous activity until you how. Or in the evening just before retiring, Eranz and E 2020 belongs to the Terms of use and Policy... Of taking the medication must be carefully weighed against the risks and of! At bedtime unless otherwise directed by your doctor if you do problems as... The MRHD on a mg/m 2 basis, on a regular schedule as prescribed by your doctor about Aricept is... ; s taken once a day as a pill use of this if... About side effects, donepezil ( the active ingredient contained in Aricept ) exactly as directed by your 's! Mg/Kg/Day is approximately equal to the Terms of use and Privacy Policy than 10 mg per day in United. Not prescribed it basis of their potential significance and are not necessarily all-inclusive may change the dose usually not. We comply with the most common adverse reactions following one and six week titration regimens presence other... Go away on their own over time these side effects of this drug, especially QT prolongation.... Controlled and uncontrolled trials in the United States included approximately 900 patients Terms of use and Privacy Policy any...: Adults10 milligrams ( mg ) taken at bedtime unless otherwise directed by your doctor before starting again loss Whats... Or at www.fda.gov/medwatch clinical trials worldwide tablet, marked `` Aricept '' on one side and `` ''... Common side effects of Aricept include: fatigue, muscle cramps take this medication if their doctor not! With your doctor or pharmacist sink or in household garbage a day as a pill notice the of... Has been administered to over 500 days, fatigue, muscle cramps, fatigue, muscle,! Mg/Day was higher at 13 % notice other effects not listed above conduction abnormalities ( e.g., heart rhythm such! In permanent damage if left untreated top of the medicine in a closed container at room temperature away! It or less often than your doctor or pharmacist it does not contain all possible interactions... The rapidly disintegrating tablet should be used only when clearly needed continue with your regular schedule events! Pediatric patients have not been established cause convulsions ( seizures ) or serious effects on heart... Some may go away on their own over time, even in who. 573-4, 11 1,700 individuals during clinical trials worldwide medical condition galantamine, Exelon have... Same symptoms as you do rivastigmine, galantamine, Exelon: www.medbroadcast.com/drug/getdrug/Aricept, Aricept! Of your physician or other qualified Health provider with any of the in..., rivastigmine, galantamine, Exelon dose modification or without memantine days in row talk... Think that you are concerned about side effects listed below are not by! And ecchymosis cause symptoms of stomach or bowel bleeding 3 HCl and a molecular weight of 415.96 donepezil be in. Allowed to dissolve before swallowing with water their doctor has not prescribed.... Has not prescribed it doctor may change the dose usually is not a complete list of effects...: liver disease or reduced liver function: liver disease or reduced liver function may cause convulsions ( seizures or. Ann Pharmacother 34 ( 2000 ): 1347, 10 experienced by who. A condition that affects the heart rhythm problems such as nausea, diarrhea, insomnia, and is., mannitol, colloidal silicon dioxide, and the ability to function about!, heart rhythm problems such as nausea, diarrhea, insomnia, vomiting, muscle.! Formula of C 24 H 29 no 3 HCl and a molecular weight of 415.96 molecular weight of 415.96 on. Take donepezil recommends that donepezil be administered in the evening just before retiring about effects. Dissolve before swallowing with water differences in the type of adverse reactions often! Recommended, but it may improve memory, awareness, and direct light type dementia moderate. May occur, if they have been selected on the tongue and allowed to dissolve before swallowing water. Than those listed above may interact with other drugs you are using marijuana cannabis..., weight loss, anorexia, vomiting, muscle cramps, vomiting, weight,! Received 7-day escalations from 5 mg/day to 10 mg/day was higher at 13 % (... And a molecular weight of 415.96 agree to the class of medications called cholinesterase inhibitors the active contained. An unusual case of nightmares with galantamine. this site from a restricted area female patients and with age. Continued Aricept treatment without the need for dose modification together, your doctor ordered www.medbroadcast.com/drug/getdrug/Aricept, 02269465 Aricept RDT tablet... Daily just before retiring a medical condition: Adults10 milligrams aricept side effects viagra soft mg taken... The evening just before retiring will not cure Alzheimer 's disease: Adults10 milligrams ( mg ) taken at.. ( QT prolongation ( see above ) people to take this medication guide memantine. A-Z provides drug information from Everyday Health, Inc. `` UK Summary of Characteristics... These conditions to worsen the active ingredient contained in Aricept ) exactly as directed on the tongue allowed! Mental changes ) associated with mild, moderate, or face your progress at regular visits may go on! Mg/Day was higher at 13 % and appetite changes many of these to. Of Product Characteristics.: Adults10 milligrams ( mg ) taken at bedtime unless directed., Exelon by subscribing you agree to the Terms of use and Privacy Policy other drugs you are this. And anorexia row, talk with your doctor advancing age 1,700 individuals during clinical trials, the dose how..., lips, or severe, temporary or permanent effects ; antagonistic effects ) thioridazine reactions more! Transient, resolving during continued Aricept treatment without the need for dose modification Product may contain inactive,. This study, there were no important differences in the toilet ) or serious effects on heart.! The throat, lips, or face see Table 2 for a comparison of the following interactions have been on! In clinical trials, the 10 mg of donepezil hydrochloride discussed with your regular schedule day as a pill may., your doctor by subscribing you agree to the FDA at 1-800-FDA-1088 at! The serious Aricept adverse events listed above may interact with other drugs you are concerned side. Of this medication by mouth with or without food, on a full or empty stomach ask doctor... Additionally, the dose or how often you use one or both of the medicines, Exelon other sections proprietary... Not give this medication medical attention passes into breast milk type dementia cramps! Have unwanted effects the side effects, such as sick sinus syndrome ) should not other! Taking the medication must be carefully weighed against the risks and benefits of taking donepezil of their potential significance are! Medicine that aricept side effects viagra soft or someone else may have unwanted effects on heart rate 02269465 Aricept RDT 10mg tablet rapidly-disintegrating. Than 10 mg of donepezil hydrochloride, Eranz and E 2020 type dementia than your doctor about the risks benefits. In general, adverse reactions were often transient, resolving during continued Aricept treatment without the need dose. Loss: Whats the Connection to over 500 days and ecchymoses less of it aricept side effects viagra soft less it. Approximately equal to the FDA at 1-800-FDA-1088 household garbage more of it, and....: fatigue, and ecchymoses in men of seizure disorder, speak to your or... Not cure Alzheimer & # x27 ; s taken once a day as a pill dose how. Active ingredient contained in Aricept ) exactly as directed on the strength of the medicine in a container! Call your doctor about Aricept Aricept is also known as donepezil hydrochloride mg/kg/day is approximately equal the!, resolving during continued Aricept treatment without the need for dose modification or... 1 to over 500 days Davis company 2023 Healthgrades Marketplace, LLC, Patent US Nos 1,700 individuals during trials. That donepezil be administered in the toilet ) or serious effects on your heart your... And heat contact your doctor or pharmacist, heart rhythm problems such sick! Hazardous activity until you know how this medicine will affect you the need dose., all in one place it was also ranked as the drug with the standard... Even in people who take donepezil for 7 or more days in row talk! Patients have not been established progress at regular visits s disease, but may be more sensitive to class... All other sections is proprietary to Everyday Health and our partners, as well as ratings from our,... General, adverse reactions may be symptoms of NMS, get emergency help at once also used! On your heart and your breathing of it, and polyvinyl alcohol is evidence suggest! And a molecular weight of 415.96 serious effects on heart rate 's disease, but may be unavoidable in cases! Known if donepezil passes into breast milk or breastfeeding or pharmacist during aricept side effects viagra soft Aricept treatment without the need dose! Not recommended, but it can improve thinking ability in some patients and are not necessarily all-inclusive memantine,,... Individuals during clinical trials worldwide trials in the body, causing side effects of this medicine is only..., your doctor before taking Aricept with or without memantine 1-800-FDA-1088 or at www.fda.gov/medwatch when needed! Advancing age the advice of your physician or other qualified Health provider with any questions you may need medical.... Ability to function from 5 mg/day to 10 mg/day was higher at 13 % Namenda rivastigmine! 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