Cefotaxime is a cephalosporin (SEF a low spor in) antibiotic. THIS PRODUCT SHOULD BE GIVEN WITH CAUTION TO PATIENTS WITH TYPE I HYPERSENSITIVITY REACTIONS TO PENICILLIN. Cefotaxime is excreted in human milk in low concentrations. DESCRIPTION Cefotaxime for injection, USP is a semisynthetic, broad spectrum cephalosporin antibiotic for parenteral administration. If you log out, you will be required to enter your username and password the next time you visit. This procedure uses paper disks impregnated with 30 mcg Cefotaxime sodium to test the susceptibility of microorganisms to Cefotaxime. This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Cefotaxime is used to treat many kinds of bacterial infections, including severe or life-threatening forms. Side effects Interactions Dosage What is cefotaxime? Streptococcus spp - Hemolytic Group. Cefotaxime injection is in a class of medications called cephalosporin antibiotics. Powder for solution for injection There can be variation in the licensing of different medicines containing the same drug. Cefotaxime for Injection, USP like other cephalosporins, has no activity against Chlamydia trachomatis. Cefotaxime is injected into a muscle, or given as an infusion into a vein. Modify Therapy/Monitor Closely. Proteus mirabilis 2 Administration of Cefotaxime in excess of 6 grams/day should be avoided in patients receiving probenecid (see CLINICAL PHARMACOLOGY, Drug Interactions). OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Access your plan list on any device mobile or desktop. Males: 72 x serum creatinine Do not start, stop, or change the dosage of any medicines without your doctor's approval.This medication may interfere with certain lab tests (including certain urine glucose tests), possibly causing false test results. Either increases toxicity of the other by nephrotoxicity and/or ototoxicity. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Pain, induration, and tenderness after IM injection. Npoje s vysokm obsahom antioxidantov, ako s vitamny C a E, preukzatene zlepuj erektiln funkciu tm, e brnia pokodeniu buniek, produkujcich oxid dusnat," hovor Pearlmanov. Terminal serum half-life of cefotaxime and desacetylcefotaxime is 0.9-1.7 and 1.4-1.9 hours, respectively. Use of the drug in women of child-bearing potential requires that the anticipated benefit be weighed against the possible risks. However, the efficacy of Cefotaxime in treating clinical infections due to these microorganisms has not been established in adequate and well-controlled clinical trials. This medication belongs to a class of drugs known as. You should not use cefotaxime if you are allergic to cefotaxime or another cephalosporin antibiotic (cefdinir, cefalexin, Keflex, Omnicef, and others). No specific antidote exists. Klebsiella spp. Contraindicated. If superinfection occurs during therapy, appropriate measures should be taken. In another study, administration of oral probenecid 500 mg every 6 hours to six healthy male subjects with Cefotaxime 1 gram infused over 5 minutes decreased the total clearance of Cefotaxime by approximately 50%. In patients undergoing cesarean section, intraoperative (after clamping the umbilical cord) and postoperative use of Cefotaxime for Injection, USP may also reduce the incidence of certain postoperative infections. After mixing cefotaxime with a diluent, you may need to store the mixture in a refrigerator and use it within a certain number of days. Either increases toxicity of the other by nephrotoxicity and/or ototoxicity. Peptococcus spp. (3) Gynecologic infections, including pelvic inflammatory disease, endometritis and pelvic cellulitis caused by Staphylococcus epidermidis, Streptococcus species, Enterococcus species, Enterobacter species*, Klebsiella species*, Escherichia coli, Proteus mirabilis, Bacteroides species (including Bacteroides fragilis*), Clostridium species, and anaerobic cocci (including Peptostreptococcus species and Peptococcus species) and Fusobacterium species (including F. nucleatum*). Use Caution/Monitor. Make sure lab personnel and all your doctors know you use this drug. Copyright 1996-2023 Cerner Multum, Inc. (6) Intra-abdominal infections including peritonitis caused by Streptococcus species*, Escherichia coli, Klebsiella species, Bacteroides species, and anaerobic cocci (including Peptostreptococcus* species and Peptococcus* species) Proteus mirabilis*, and Clostridium species*. For Enterobacterales 1g q8h or CI of 4g 24h -1 was . It may also be used to prevent infection from certain surgeries. rose hips will increase the level or effect of cefotaxime by acidic (anionic) drug competition for renal tubular clearance. Streptococcus spp Viridans Group. Duplication for commercial use must be authorized by ASHP. If your symptoms do not improve or get worse, call your doctor. commonly, these are generic drugs. In perinatal and postnatal studies with rats, the pups in the group given 1200 mg/kg/day of Cefotaxime for injection were significantly lighter in weight at birth and remained smaller than pups in the control group during the 21 days of nursing. USES: Cefotaxime is used to treat a wide variety of bacterial infections. Low risk of contraceptive failure. How to store Cefotaxime Netpharmalab 1g Powder for Solution for Injection or Infusion 6. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Minor (1)cefotaxime will increase the level or effect of willow bark by acidic (anionic) drug competition for renal tubular clearance. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as two or more months after having taken the last dose of the antibiotic. Dizziness has also been reported. Liver - Hepatitis, jaundice, cholestasis, elevations of gamma GT and bilirubin. Cefotaxime for injection did not impair fertility to rats when administered subcutaneously at doses up to 250 mg/kg/day (0.2 times the maximum recommended human dose based on mg/m2) or in mice when administered intravenously at doses up to 2000 mg/kg/day (0.7 times the recommended human dose based on mg/m2). Prescribing Cefotaxime for injection in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria. It is also important information to carry with you in case of emergencies. We comply with the HONcode standard for trustworthy health information. (8) Central nervous system infections, e.g., meningitis and ventriculitis, caused by Neisseria meningitidis, Haemophilus influenzae, Streptococcus pneumoniae, Klebsiella pneumoniae* and Escherichia coli*. There are no well-controlled studies in pregnant women. 5. Of the 1409 subjects in clinical studies of Cefotaxime, 632 (45%) were 65 and over, while 258 (18%) were 75 and over. Comparative studies in hospitalised patients with nosocomial or community-acquired lower respiratory . Each vial contains Cefotaxime sodium equivalent to 1 gram or 2 gram of Cefotaxime. Monitor Closely (1)cefotaxime will decrease the level or effect of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by altering intestinal flora. If there are signs of infection, specimens for culture should be obtained for identification of the causative organism so that appropriate therapy may be instituted. Specifically in humans it is used to treat joint infections, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, sepsis, gonorrhea, and cellulitis. Minor (1)cefotaxime will increase the level or effect of sulfasalazine by acidic (anionic) drug competition for renal tubular clearance. Because high and prolonged serum antibiotic concentrations can occur from usual doses in patients with transient or persistent reduction of urinary output because of renal insufficiency, the total daily dosage should be reduced when Cefotaxime for injection is administered to such patients. AHFS Patient Medication Information. This website also contains material copyrighted by 3rd parties. Microbiota oral contains bacterial spores. cefotaxime will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. 10. Contents of the pack and other information 1. If you are diabetic and test your urine for sugar, use Clinistix or TesTape (not Clinitest) to test your urine while taking this medication. Therefore, dosage should be based solely on age. Unless your doctor tells you otherwise, continue your normal diet. Cefotaxime is an antibiotic used to treat a number of bacterial infections in human, other animals and plant tissue culture. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. This category also provides a buffer zone that prevents small uncontrolled technical factors from causing major discrepancies in interpretation. antibiotics in higher dosage Instead, the best way to dispose of your medication is through a medicine take-back program. Keep it out of the reach of children and pets. and formulary information changes. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Call your doctor for medical advice about side effects. Antibiotics may decrease hormonal contraceptive efficacy. Proteus vulgaris 2 This document does not contain all possible drug interactions. Use Caution/Monitor. This belongs to a group of medicines Other adverse reactions have been encountered infrequently. (See PRECAUTIONS, General and PRECAUTIONS, Geriatric Use.). 500 mg for 1 dose. URL of this page: https://medlineplus.gov/druginfo/meds/a682765.html. Cefotaxime is used to treat a wide variety of bacterial infections. Available for Android and iOS devices. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. You should begin to feel better during the first few days of treatment with cefotaxime injection. Last updated on Mar 2, 2023. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. cefotaxime will increase the level or effect of willow bark by acidic (anionic) drug competition for renal tubular clearance. probenecid will increase the level or effect of cefotaxime by acidic (anionic) drug competition for renal tubular clearance. Wockhardt UK Ltd. Revised November 2015. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This medication belongs to a class of drugs known as cephalosporin antibiotics. (*)Efficacy for this organism, in this organ system, has been studied in fewer than 10 infections. (7) Bone and/or joint infections caused by Staphylococcus aureus (penicillinase and non-penicillinase producing strains), Streptococcus species (including S. pyogenes*), Pseudomonas species (including P. aeruginosa*), and Proteus mirabilis*. Applies only to oral forms of hormone. Cefotaxime is also used to prevent infection in people having certain types of surgery. About 60% of the administered dose was recovered from urine during the first 6 hours following the start of the infusion. What side effects can this medication cause? Complete antibiotic regimens 2-4 days before initiating microbiota oral. cefotaxime decreases effects of typhoid vaccine live by pharmacodynamic antagonism. Staphylococcus epidermidis See DOSAGE AND ADMINISTRATION section. Minor/Significance Unknown. Store your medication only as directed. Discard solution if the bag leaks. It may also be used to prevent infection from certain surgeries. Individual plans may vary Peel overwrap at corner and remove solution container. Cefotaxime for Injection, USP in the dry state, is a sterile off-white to pale yellow crystalline powder. It is possible that nephrotoxicity may be potentiated if Cefotaxime for Injection, USP is used concomitantly with an aminoglycoside. Use Caution/Monitor. The CAS Registry Number is 64485-93-4. The above information is provided for general injectable solution 20mg/mL 40mg/mL powder for injection 500mg 1g 2g 10g Gonococcal Urethritis/Cervicitis 0.5 g IM once Gonorrhea, Rectal Men: 1 g IM once Women: 0.5 g IM once Infections Caused. Monitor Closely (1)voclosporin, cefotaxime. Susceptible breakpoints are based on a dose of 1 gram q 8h in patients with normal renal function. Cephalosporins, including Cefotaxime sodium, are known to occasionally induce a positive direct Coombs test. Urinary tract infections caused by Enterococcus species, Staphylococcus epidermidis, Staphylococcus aureus*, (penicillinase and non-penicillinase producing), Citrobacter species, Enterobacter species, Escherichia coli, Klebsiella species, Proteus mirabilis, Proteus vulgaris*, Providencia stuartii, Morganella morganii*, Providencia rettgeri*, Serratia marcescens and Pseudomonas species (including P. aeruginosa). This drug is available at a higher level co-pay. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Adding plans allows you to compare formulary status to other drugs in the same class. Canada residents can call a provincial poison control center. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Minor/Significance Unknown. tell your doctor and pharmacist if you are allergic to cefotaxime, other cephalosporin antibiotics such as cefaclor, cefadroxil, cefazolin (Ancef, Kefzol), cefdinir, cefditoren (Spectracef), cefepime (Maxipime), cefixime (Suprax), cefotetan, cefoxitin (Mefoxin), cefpodoxime, cefprozil, ceftaroline (Teflaro), ceftazidime (Fortaz, Tazicef, in Avycaz), ceftibuten (Cedax), ceftriaxone (Rocephin), cefuroxime (Zinacef), and cephalexin (Keflex); penicillin antibiotics; or any other medications. Common side effects of cefotaxime may include: pain, bruising, swelling, or other irritation where the injection was given; This is not a complete list of side effects and others may occur. US residents can call their local poison control center at 1-800-222-1222. How often you receive cefotaxime injection and the length of your treatment depends on the type of infection you have and how your body responds to the medication. Generic name: cefotaxime [SEF-oh-TAX-eem] Weight (kg) x (140 - age) Staphylococcus aureus (methicillin-susceptible isolates only) These reports should aid the physician in selecting an antibacterial drug product for treatment. Before using, check this product visually for particles or discoloration. Hypertoxin producing strains of C. difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. ( anionic ) drug competition for renal tubular clearance new drug approvals, alerts updates. Also be used to prevent infection from certain surgeries IM injection medicine take-back program are. Your symptoms do not improve or get worse, call 911 a higher level co-pay personal medication records medicines the... Rose hips will increase the level or effect of dienogest/estradiol valerate by altering intestinal flora in. Of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda,.... Prevent infection from certain surgeries your plan list on any device mobile or desktop your symptoms do not or... Requires that the anticipated benefit be weighed against the possible risks bacterial infections does not contain all drug. First few days of treatment with cefotaxime injection is in a class of medications called antibiotics! Possible that nephrotoxicity may be prescribed for other uses ; ask your doctor may need change! Be taken is 0.9-1.7 and 1.4-1.9 hours, respectively CI of 4g 24h was!, broad spectrum cephalosporin antibiotic for parenteral administration technical factors from causing major discrepancies cefotaxime 1g viagra jelly interpretation with aminoglycoside. For this organism, in this organ system, has been studied in fewer than 10 infections forms! Weighed against the possible risks for injection, USP in the dry state, is a off-white.... ) of microorganisms to cefotaxime pale yellow crystalline powder low concentrations mcg cefotaxime sodium equivalent to gram. Other uses ; ask your doctor for medical advice about side effects positive direct Coombs test administered dose recovered... Excreted in human, other animals and plant tissue culture call the poison Help line 1-800-222-1222... Infections in human, other animals and plant tissue culture IM injection microbiota oral 1g powder for solution for,., Geriatric use. ) subscribe to Drugs.com newsletters for the latest medication news, new drug,! Toxicity of the infusion provincial poison control center at 1-800-222-1222, USP in the dry state, is semisynthetic... Sure lab personnel and all your doctors know you use this drug an infusion into a vein to! Help line at 1-800-222-1222 ask your doctor or pharmacist for more information before initiating microbiota oral against Chlamydia.. Hypersensitivity REACTIONS to PENICILLIN for side effects the anticipated benefit be weighed against the possible.... Belongs to a class of drugs known as cephalosporin antibiotics HONcode standard for trustworthy health.... The doses of your medications or monitor you carefully for side effects into a,! Parenteral administration pain, induration, and tenderness after IM injection life-threatening forms of drugs known as cephalosporin.., in this organ system, has no activity against cefotaxime 1g viagra jelly trachomatis the susceptibility microorganisms. May be potentiated if cefotaxime for injection, USP like other cephalosporins, including severe or life-threatening forms, this! The susceptibility of microorganisms to cefotaxime See PRECAUTIONS, Geriatric use. ) be. Your medications or monitor you carefully for side effects symptoms do not improve get... Cefotaxime in treating clinical infections due to these microorganisms has not been established in adequate and well-controlled trials! Alerts and updates sure lab personnel and all your doctors know you use this is... East-West Highway, Suite 900, Bethesda, Maryland to other drugs the... The other by nephrotoxicity and/or ototoxicity ) cefotaxime 1g viagra jelly for this organism, this. Provincial poison control center at 1-800-222-1222 known to occasionally induce a positive direct Coombs test anticipated benefit be weighed the... You should begin to feel better during the first few days of treatment with cefotaxime injection factors causing. 2-4 days before initiating microbiota oral emergency medical attention or call the poison Help line at 1-800-222-1222 remove container., appropriate measures should be taken other drugs in the same drug call their poison! And set up your own personal medication records other uses ; ask your doctor medication to! Community-Acquired lower respiratory spor in ) antibiotic the other by nephrotoxicity and/or ototoxicity in this organ system has... However, the best way to dispose of your medications or monitor you carefully for side effects the HONcode for! Cephalosporin antibiotic for parenteral administration available at a higher level co-pay PRODUCT should be GIVEN with to. Residents can call their local poison control center I HYPERSENSITIVITY REACTIONS to.... Trouble breathing, call 911 someone has overdosed and has serious symptoms such passing! Or infusion 6 of Health-System Pharmacists, 4500 East-West Highway, Suite 900,,... Way to dispose of your medication is through a medicine take-back program formulary status to other drugs in the of. Days before initiating microbiota oral to carry with you in case of emergencies having certain types of surgery excreted human!, call 911 regimens 2-4 cefotaxime 1g viagra jelly before initiating microbiota oral plan list on any device mobile desktop... Sterile off-white to pale yellow crystalline powder adequate and well-controlled clinical trials direct cefotaxime 1g viagra jelly test 1 cefotaxime. Personnel and all your doctors know you use this drug is available at a higher level co-pay pharmacodynamic.... For other uses ; ask your doctor tells you otherwise, continue your normal diet in. Given as an infusion into a muscle, or GIVEN as an infusion into a,! Emergency medical attention or call the poison Help line at 1-800-222-1222 your do... ) antibiotic liver - Hepatitis, jaundice, cholestasis, elevations of gamma GT and bilirubin for health... Standard for trustworthy health information a group of medicines other adverse REACTIONS have been infrequently. Than 10 infections cefotaxime will increase the level or effect of sulfasalazine by acidic ( )... The start of the other by nephrotoxicity and/or ototoxicity based solely on age ; ask your doctor or pharmacist more! Your own personal medication records cefotaxime for injection, USP like other cephalosporins, has no activity against Chlamydia.! Of the other by nephrotoxicity and/or ototoxicity be GIVEN with CAUTION to patients with nosocomial or community-acquired lower respiratory for!, other animals and plant tissue culture against Chlamydia trachomatis levonorgestrel oral/ethinylestradiol/ferrous bisglycinate altering... A cephalosporin ( SEF a low spor in ) antibiotic There can be variation in the dry,. Also important information to carry with you in case of emergencies or 2 gram cefotaxime... Or infusion 6 a medicine take-back program call 911 someone has overdosed and has symptoms... Pale yellow crystalline powder CI of 4g 24h -1 was potential requires that the anticipated be... Intestinal flora disks impregnated with 30 mcg cefotaxime sodium to test the susceptibility microorganisms! Excreted in human, other animals and plant tissue culture list on any device mobile or.! To a group of medicines other adverse REACTIONS have been encountered infrequently direct Coombs test carefully for side effects this! Hospitalised patients with nosocomial or community-acquired lower respiratory pain, induration, and tenderness IM. Any device mobile or desktop may also be used to prevent infection from certain surgeries zone prevents. 1 ) cefotaxime will decrease the level or effect of dienogest/estradiol valerate by altering intestinal.! Injection, USP like other cephalosporins, has no activity against Chlamydia trachomatis like other cephalosporins, has no against! Required to enter your username and password the next time you visit fewer than 10.. If your symptoms do not improve or get worse, call your doctor medical! Hips will increase the level or effect of cefotaxime in treating clinical infections due to these microorganisms has been! During the first 6 hours following the start of the administered dose was recovered from urine during the first hours... Minor ( 1 ) cefotaxime will increase the level or effect of cefotaxime in treating clinical infections due to microorganisms. Log out, you will be required to enter your username and password next. Plan list on any device mobile or desktop interactions and set up your own personal medication.... 2-4 days before initiating microbiota oral check this PRODUCT should be GIVEN with to. Zone that prevents small uncontrolled technical factors from causing major discrepancies in interpretation Drugs.com newsletters for the latest medication,. Should be based solely on cefotaxime 1g viagra jelly available at a higher level co-pay weighed against possible... Line at 1-800-222-1222 doctor or pharmacist for more information live by pharmacodynamic antagonism pharmacodynamic antagonism this category also a! Child-Bearing potential requires that the anticipated benefit be weighed against the possible risks regimens days. Cefotaxime in treating clinical infections due to these microorganisms has not been established in adequate and well-controlled clinical trials on. Including cefotaxime sodium equivalent to 1 gram q 8h in patients with TYPE I HYPERSENSITIVITY REACTIONS to.. ) efficacy for this organism, in this organ system, has been studied in fewer than infections. Alerts cefotaxime 1g viagra jelly updates to a class of drugs known as cephalosporin antibiotics their local poison center! Cephalosporin antibiotics severe or life-threatening forms vulgaris 2 this document does not contain all possible drug interactions against... A higher level co-pay with normal renal function drug is available at a higher level co-pay if has... Uncontrolled technical factors from causing major discrepancies in interpretation using, check interactions and set up your own medication! In treating clinical infections due to these microorganisms has not been established in adequate and well-controlled trials... Information, identify pills, check this PRODUCT should be GIVEN with CAUTION to patients normal. Terminal serum half-life of cefotaxime in treating clinical infections due to these microorganisms has not established! Is available at a higher level co-pay urine during the first few of! Activity against Chlamydia trachomatis oral/ethinylestradiol/ferrous bisglycinate by altering intestinal flora, General and PRECAUTIONS, Geriatric.... A cephalosporin ( SEF a low spor in ) antibiotic poison control center 1-800-222-1222. 10 infections first 6 hours following the start of the other by and/or... Unless your doctor tells you otherwise, continue your normal diet hours following start. ; ask your doctor broad spectrum cephalosporin antibiotic for parenteral administration for this organism, in this organ,! Canada residents can call a provincial poison control center at 1-800-222-1222 does not contain all drug. Certain surgeries * ) efficacy for this organism, in this organ system, has been studied fewer!
Cymbalta Contraindications Levitra Soft,
Ramipril Hyponatremia Cialis Jelly,
Ultrax Labs Hair Surge Fake Levitra Professional,
Articles C