Avoid or Use Alternate Drug. sulfamethoxazole and lumefantrine both increase QTc interval. Reduce selexipag dose to once daily if coadministered with moderate CYP2C8 inhibitors. Avoid or Use Alternate Drug. Use Caution/Monitor. Minor/Significance Unknown. Use Caution/Monitor. Minor (2)trimethoprim will decrease the level or effect of biotin by altering intestinal flora. First-line antibiotics for acute, uncomplicated urinary tract infections ( UTIs) typically include: Fosfomycin. Coadministration may impair renal clearance of amantadine, resulting in higher plasma concentrations. Modify Therapy/Monitor Closely. Leucorvorin, reduced folates, and folate antimetabolites are substrates for glucarpidase (hydrolyzes glutamate residue from folic acid and antifolates). Use Caution/Monitor. For 2 weeks after abametapir application, avoid taking drugs that are CYP3A4 substrates. idelalisib will increase the level or effect of trimethoprim by affecting hepatic/intestinal enzyme CYP3A4 metabolism. What drugs should be avoided with a sulfa allergy? Paclitaxel levels/toxicity may increase when coadministered with CYP2C8 inhibitors, trimethoprim will increase the level or effect of paclitaxel protein bound by Other (see comment). Avoid or Use Alternate Drug. Hyperkalemia. Minor/Significance Unknown. Monitor Closely (2)sulfamethoxazole and itraconazole both increase QTc interval. sulfamethoxazole and ibutilide both increase QTc interval. Adjust dose according to prescribing information if needed. dofetilide will increase the level or effect of trimethoprim by basic (cationic) drug competition for renal tubular clearance. Modify Therapy/Monitor Closely. Use Caution/Monitor. Serious - Use Alternative (1)sulfamethoxazole, pretomanid. Monitor Closely (2)sulfamethoxazole and foscarnet both increase QTc interval. Either increases toxicity of the other by Other (see comment). alpelisib will decrease the level or effect of trimethoprim by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor. Monitor Closely (1)tecovirimat will decrease the level or effect of trimethoprim by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Minor/Significance Unknown. Minor/Significance Unknown. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Minor (1)tranylcypromine increases levels of sulfamethoxazole by unspecified interaction mechanism. Use Caution/Monitor. Monitor Closely (1)imatinib will increase the level or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism. trimethoprim and venlafaxine both increase QTc interval. Use Caution/Monitor. Risk of hyponatremia. Monitor Closely (2)epinephrine racemic and sulfamethoxazole both increase QTc interval. butabarbital will decrease the level or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism. tafenoquine will increase the level or effect of trimethoprim by Other (see comment). Modify Therapy/Monitor Closely.Minor (1)sulfamethoxazole decreases levels of desipramine by unspecified interaction mechanism. Avoid or Use Alternate Drug. sulfamethoxazole will increase the level or effect of ethotoin by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor. quinine will increase the level or effect of trimethoprim by basic (cationic) drug competition for renal tubular clearance. Monitor Closely (1)sulfamethoxazole will increase the level or effect of ethotoin by affecting hepatic enzyme CYP2C9/10 metabolism. Monitor Closely (1)efavirenz will increase the level or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism. Avoid or Use Alternate Drug.Minor (3)indapamide, trimethoprim. During administration of 800 mg sulfamethoxazole and 160 mg trimethoprim b.i.d., the mean steady-state plasma concentration of trimethoprim was 1.72 g/mL. Minor/Significance Unknown. Minor/Significance Unknown. May cause hyperkalemia, particularly with high doses, renal insufficiency, or when combined with other drugs that cause hyperkalemia.Serious - Use Alternative (2)sulfamethoxazole and pentamidine both increase QTc interval. Modify Therapy/Monitor Closely. Use Caution/Monitor.Minor (1)sulfamethoxazole will increase the level or effect of tolbutamide by affecting hepatic enzyme CYP2C9/10 metabolism. Trimethoprim decreases urinary potassium excretion. If you miss a dose of this medicine, take it as soon as possible. Trimethoprim decreases urinary potassium excretion. sulfamethoxazole will decrease the level or effect of ethinylestradiol by altering intestinal flora. To make sure you can safely take Bactrim, tell your doctor if you have ever had: an electrolyte imbalance (such as low blood sodium or high potassium); porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or. Applies only to oral forms of hormone. quinidine will increase the level or effect of sulfamethoxazole by basic (cationic) drug competition for renal tubular clearance. sulfamethoxazole and ketoconazole both increase QTc interval. Mechanism: unspecified interaction mechanism. Use Caution/Monitor. sulfamethoxazole and nilotinib both increase QTc interval. Tell your doctor if you have diarrhea that is watery or bloody. Serious - Use Alternative (1)tafenoquine will increase the level or effect of trimethoprim by Other (see comment). Monitor Closely (1)sulfamethoxazole will increase the level or effect of eltrombopag by affecting hepatic enzyme CYP2C9/10 metabolism. Monitor Closely (1)trimethoprim and pentamidine both increase serum potassium. Trimethoprim decreases urinary potassium excretion. Minor/Significance Unknown. Low risk of contraceptive failure. Most Mechanism: unspecified interaction mechanism. If coadministration is unavoidable, monitor patients for loss of therapeutic effect of these drugs.ivosidenib will decrease the level or effect of trimethoprim by affecting hepatic enzyme CYP2C9/10 metabolism. Applies only to oral forms of hormone. Trimethoprim decreases urinary potassium excretion. For oral dosage forms (liquid or tablets): Adults1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 10 to 14 days. sulfamethoxazole and fluconazole both increase QTc interval. Use Caution/Monitor. Modify Therapy/Monitor Closely. Monitor Closely (2)sulfamethoxazole and ziprasidone both increase QTc interval. Minor/Significance Unknown. Contraindicated. Use Caution/Monitor.fluvoxamine and sulfamethoxazole both increase QTc interval. Risk of hyponatremia. pharmacodynamic antagonism. Use Caution/Monitor. trimethoprim will decrease the level or effect of mestranol by altering intestinal flora. Avoid or Use Alternate Drug. Use Caution/Monitor. Minor/Significance Unknown. cyclophosphamide will increase the level or effect of trimethoprim by affecting hepatic/intestinal enzyme CYP3A4 metabolism. present in the blood 24 hours after drug administration. sulfamethoxazole and ranolazine both increase QTc interval. Modify Therapy/Monitor Closely. Continue reading, Septra, Sulfatrim, Septra DS, Cotrim, Sulfatrim Pediatric. Hyperkalemia. methoxsalen, sulfamethoxazole. Modify Therapy/Monitor Closely.promazine and trimethoprim both increase QTc interval. Monitor Closely (2)chlorpromazine and sulfamethoxazole both increase QTc interval. flecainide and trimethoprim both increase QTc interval. Trimethoprim decreases urinary potassium excretion. Trimethoprim decreases urinary potassium excretion. The above information is provided for general Use Caution/Monitor.foscarnet and trimethoprim both increase QTc interval. Risk of hyponatremia.hydrochlorothiazide increases levels of sulfamethoxazole by unspecified interaction mechanism. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor. trimethoprim will increase the level or effect of selexipag by decreasing metabolism. Minor/Significance Unknown. imipramine and trimethoprim both increase QTc interval. Modify Therapy/Monitor Closely.protriptyline and trimethoprim both increase QTc interval. sulfamethoxazole will decrease the level or effect of pyridoxine by altering intestinal flora. Risk of hyponatremia. Modify Therapy/Monitor Closely. May cause hyperkalemia, particularly with high doses, renal insufficiency, or when combined with other drugs that cause hyperkalemia. Monitor Closely (2)sulfamethoxazole will increase the level or effect of procainamide by basic (cationic) drug competition for renal tubular clearance. levoketoconazole will increase the level or effect of trimethoprim by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious - Use Alternative (2)sulfamethoxazole increases effects of dalteparin by decreasing metabolism. Modify Therapy/Monitor Closely. Trimethoprim decreases urinary potassium excretion. Minor/Significance Unknown. ibutilide and trimethoprim both increase QTc interval. mesalamine increases levels of sulfamethoxazole by unspecified interaction mechanism. Modify Therapy/Monitor Closely. Minor/Significance Unknown. finished bactrim on thursday, today is saturday and i just noticed a decent sized bruise on back of thigh. Enhanced photosensitivity. Monitor Closely (2)haloperidol and trimethoprim both increase QTc interval. Minor (1)linezolid increases levels of sulfamethoxazole by unspecified interaction mechanism. Mechanism: pharmacodynamic synergism. Modify Therapy/Monitor Closely.Minor (1)sulfamethoxazole decreases levels of amoxapine by unspecified interaction mechanism. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Mechanism: pharmacodynamic synergism. phenelzine increases levels of sulfamethoxazole by unspecified interaction mechanism. Complete antibiotic regimens 2-4 days before initiating microbiota oral. Avoid or Use Alternate Drug. Order by 10pm (subject to change during promotions), available 7 days a week for 4.95. Minor/Significance Unknown. Generic name: sulfamethoxazole and trimethoprim [SUL-fa-meth-OX-a-zole-and-trye-METH-oh-prim] Monitor Closely (2)desipramine and sulfamethoxazole both increase QTc interval. Low risk of contraceptive failure. Minor (1)isavuconazonium sulfate will increase the level or effect of trimethoprim by Other (see comment). May cause hyperkalemia, particularly with high doses, renal insufficiency, or when combined with other drugs that cause hyperkalemia. sulfamethoxazole and venlafaxine both increase QTc interval. affecting hepatic enzyme CYP2C9/10 metabolism. Applies only to oral forms of hormone. Minor (3)chlorothiazide increases levels of sulfamethoxazole by unspecified interaction mechanism. Finerenone dose adjustment based on current serum potassium concentration. Monitor Closely (2)fluoxetine and trimethoprim both increase QTc interval. Avoid or Use Alternate Drug. Use Caution/Monitor. Available for Android and iOS devices. Minor/Significance Unknown.sulfamethoxazole will decrease the level or effect of balsalazide by altering intestinal flora. Symptom relief is often seen within 3 days of starting treatment. Use Caution/Monitor. paliperidone and trimethoprim both increase QTc interval. Use Caution/Monitor. Avoid sunlight or tanning beds. sulfamethoxazole will decrease the level or effect of conjugated estrogens by altering intestinal flora. Mechanism: unspecified interaction mechanism. Monitor Closely (1)lenacapavir will increase the level or effect of trimethoprim by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Modify Therapy/Monitor Closely.Minor (1)sulfamethoxazole decreases levels of doxepin by unspecified interaction mechanism. Use Caution/Monitor. balsalazide increases levels of sulfamethoxazole by unspecified interaction mechanism. Monitor Closely (1)encorafenib, trimethoprim. Avoid or Use Alternate Drug.Minor (1)sulfamethoxazole decreases levels of pimozide by unspecified interaction mechanism. Avoid or Use Alternate Drug. Use Caution/Monitor. Minor (1)torsemide increases levels of sulfamethoxazole by unspecified interaction mechanism. Use Caution/Monitor. Coadministration of siponimod with drugs that cause moderate CYP2C9 AND a moderate or strong CYP3A4 inhibition is not recommended. Minor/Significance Unknown. epinephrine racemic and sulfamethoxazole both increase QTc interval. Hyperkalemia. methyclothiazide will increase the level or effect of trimethoprim by basic (cationic) drug competition for renal tubular clearance. Avoid coadministration of sensitive CYP3A4 substrates with ivosidenib or replace with alternative therapies. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely.Minor (1)fluconazole will increase the level or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism. triamterene, trimethoprim. Monitor Closely (1)sulfamethoxazole will increase the level or effect of carvedilol by affecting hepatic enzyme CYP2C9/10 metabolism. rifampin will decrease the level or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism. Serious - Use Alternative (2)sulfamethoxazole and indapamide both increase QTc interval. Avoid or Use Alternate Drug. sulfamethoxazole, imidapril. Minor (3)cyclopenthiazide, trimethoprim. ketoconazole will increase the level or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. leucovorin decreases effects of trimethoprim by pharmacodynamic antagonism. Comment: Trimethoprim may increase risk of methotrexate-induced bone marrow suppression and megaloblastic anemia. Modify Therapy/Monitor Closely. sulfamethoxazole increases effects of enoxaparin by decreasing metabolism. Risk of hyponatremia. Minor (1)ganciclovir increases toxicity of sulfamethoxazole by pharmacodynamic synergism. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Minor/Significance Unknown. Avoid coadministration of pexidartinib with other products know to cause hepatoxicity. Use Caution/Monitor. Minor (1)aspirin rectal increases levels of sulfamethoxazole by unspecified interaction mechanism. May cause hyperkalemia, particularly with high doses, renal insufficiency, or when combined with other drugs that cause hyperkalemia. Mechanism: pharmacodynamic synergism. Modify Therapy/Monitor Closely. The steady-state mean plasma levels of free and total sulfamethoxazole were 57.4 g/mL and 68.0 g/mL, respectively. sulfamethoxazole will decrease the level or effect of pyridoxine by altering intestinal flora. Bactrim is the brand name of a combination medicine that contains the antibiotics sulfamethoxazole and trimethoprim. Monitor Closely (2)erythromycin lactobionate and trimethoprim both increase QTc interval. A 21-year-old female asked: Was prescribed bactrim ds for 7 days, take 2 800mg doses a day. trimethoprim will increase the level or effect of tucatinib by Other (see comment). Monitor Closely (2)imipramine and sulfamethoxazole both increase QTc interval. Modify Therapy/Monitor Closely.fluphenazine and sulfamethoxazole both increase QTc interval. Monitor Closely (2)trimethoprim will decrease the level or effect of estropipate by altering intestinal flora. Take Bactrim exactly as prescribed by your doctor. Avoid coadministration of sensitive CYP3A4 substrates with ivosidenib or replace with alternative therapies. Use Caution/Monitor. Bactrim should not be given to a child younger than 2 months old. Monitor Closely (1)trimethoprim and fosinopril both increase serum potassium. Disulfiram like reaction. Isavuconazonium sulfate, an OCT2 inhibitor, may increase the effects or levels of OCT2 substrates. Consider decreasing lacosamide dose when coadministered with strong CYP2C9 inhibitors. Modify Therapy/Monitor Closely.sulfamethoxazole and octreotide (Antidote) both increase QTc interval. Applies only to oral form of both agents. sulfamethoxazole and droperidol both increase QTc interval. Weighing 24 kg3 teaspoonfuls (15 mL) or 1 tablets 4 times a day for 14 to 21 days. itraconazole and trimethoprim both increase QTc interval. quinidine will increase the level or effect of trimethoprim by basic (cationic) drug competition for renal tubular clearance. protriptyline and sulfamethoxazole both increase QTc interval. Minor (1)nitazoxanide, sulfamethoxazole. Copyright 1996-2023 Cerner Multum, Inc. Low risk of contraceptive failure. Modify Therapy/Monitor Closely. trimethoprim will increase the level or effect of erdafitinib by affecting hepatic enzyme CYP2C9/10 metabolism. promazine increases toxicity of sulfamethoxazole by unspecified interaction mechanism. Minor/Significance Unknown. Minor (1)sulfamethoxazole and pazopanib both increase QTc interval. Can I drink alcohol when taking sulfamethoxazole / trimethoprim DS? Modify Therapy/Monitor Closely. trimethoprim and telmisartan both increase serum potassium. trimethoprim and potassium chloride both increase serum potassium. Minor/Significance Unknown. sulfamethoxazole, ospemifene. Coadministration of encorafenib with sensitive CYP3A4 substrates may result in increased toxicity or decreased efficacy of these agents. Minor (1)sulfamethoxazole, aminohippurate sodium. Modify Therapy/Monitor Closely. Brand names: Bactrim, Bactrim DS Either increases toxicity of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. If unable to avoid coadministration with strong CYP2C9 inhibitors, monitor closely for adverse reactions and consider decreasing dose accordingly. Use Caution/Monitor. Minor/Significance Unknown. Minor/Significance Unknown. Avoid or Use Alternate Drug. Microbiota oral contains bacterial spores. Use Caution/Monitor. Avoid or Use Alternate Drug. If coadministration cannot be avoided, monitor for substrate-related toxicities and consider dosage reduction if needed based on product labeling of the coadministered drug. sulfamethoxazole and erythromycin stearate both increase QTc interval. Avoid administering other phototoxic drugs with aminolevulinic acid oral for 24 hr during perioperative period. Minor (1)probenecid increases levels of sulfamethoxazole by unspecified interaction mechanism. Modify Therapy/Monitor Closely. sulfamethoxazole will increase the level or effect of flurbiprofen by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. Avoid or Use Alternate Drug. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Drinking extra water will help to prevent some unwanted effects (eg, crystals in the urine). Minor/Significance Unknown. istradefylline will increase the level or effect of trimethoprim by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug.amiodarone and trimethoprim both increase QTc interval. Other (see comment). Minor/Significance Unknown. Monitor Closely (2)octreotide and trimethoprim both increase QTc interval. Minor/Significance Unknown. Trimethoprim and sulfamethoxazole have a greater effect when given together than when given separately, because they inhibit successive steps in the folate synthesis pathway. Acute exacerbations of chronic bronchitis due to susceptible strains of Streptococcus pneumoniae or Haemophilus influenzae, Documented Pneumocystis jiroveci pneumonia (PCP); also, prophylaxis against PCP in individuals who are immunosuppressed, Enteritis caused by susceptible strains of Shigella flexneri and S sonnei, Alternatively, 8-10 mg TMP/kg/day IV divided q6-12hr for up to 5 days, Traveler's diarrhea due to susceptible strains of enterotoxigenic Escherichia coli, UTIs caused by susceptible strains of Escherichia coli, Klebsiella species, Enterobacter species, Morganella morganii, Proteus mirabilis, and Proteus vulgaris, Pyelonephritis: 1 DS tab or 2 regular-strength tabs PO q12hr x 14 days, Prostatitis: 1 DS tab or 2 regular-strength tabs PO q12hr x 14 days or 2-3 months if chronic infection, A 3 to 5 day course may be used for acute, uncomplicated cystitis, Prophylaxis (off-label): Various regimens exist; may use regular-strength tablet once/twice per week, 1 DS tab or 1 regular-strength tab PO qDay or q12hr for up to 18 weeks, Acute otitis media in pediatric patients due to susceptible strains of Streptococcus pneumoniae or Haemophilus influenzae, >2 months: 6-10 mg TMP/kg/day PO divided q12hr for 10 days, 8-12 mg TMP/kg/day PO divided q12hr for 5-10 days; add beta-lactam antibiotic to regimen if beta-hemolytic Streptococcus spp also suspected. cimetidine will increase the level or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism. It blocks two steps in the production of proteins and nucleic acids that bacteria need to survive. Avoid or Use Alternate Drug. nortriptyline and sulfamethoxazole both increase QTc interval. May cause hyperkalemia, particularly with high doses, renal insufficiency, or when combined with other drugs that cause hyperkalemia. This website also contains material copyrighted by 3rd parties. Coadministration of tucatinib (a CYP2C8 substrate) with a strong or moderate CYP2C8 inhibitors increases tucatinib plasma concentrations and risk of toxicities.tucatinib will increase the level or effect of trimethoprim by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Several FDA-approved drug labels may be available for sulfamethoxazole / trimethoprim. Many drugs can interact with sulfamethoxazole and trimethoprim, especially: amantadine, digoxin, cyclosporine, indomethacin, leucovorin, methotrexate, procainamide, pyrimethamine; an "ACE inhibitor" heart or blood presure medication (benazepril, enalapril, lisinopril, quinapril, ramipril, and others); or. levoleucovorin decreases effects of trimethoprim by pharmacodynamic antagonism. All forms of Bactrim are available as generic drugs. crofelemer increases levels of trimethoprim by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. amiodarone will increase the level or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism. Avoid or Use Alternate Drug. Trimethoprim decreases urinary potassium excretion. Minor/Significance Unknown.trimethoprim will decrease the level or effect of pyridoxine (Antidote) by altering intestinal flora. Minor/Significance Unknown. Minor/Significance Unknown. Monitor Closely (2)erythromycin ethylsuccinate and trimethoprim both increase QTc interval. Minor/Significance Unknown.trimethoprim will decrease the level or effect of thiamine by altering intestinal flora. sulfamethoxazole will increase the level or effect of erdafitinib by affecting hepatic enzyme CYP2C9/10 metabolism. trimethoprim and potassium citrate both increase serum potassium. Use Caution/Monitor. Avoid or Use Alternate Drug. 4 times a day for 14 to 21 days: Fosfomycin avoid coadministration with strong CYP2C9,! Need to survive bone marrow suppression and megaloblastic anemia a 21-year-old female asked: was prescribed bactrim DS 7! Trimethoprim [ SUL-fa-meth-OX-a-zole-and-trye-METH-oh-prim ] monitor Closely ( 1 ) ganciclovir increases toxicity of the other by pharmacodynamic synergism increase! Brand name of a combination medicine that contains the antibiotics sulfamethoxazole and trimethoprim increase! 2-4 days before initiating microbiota oral than 2 months old ) fluconazole will increase the or! Or strong CYP3A4 inhibition is not recommended of erdafitinib by affecting hepatic enzyme CYP2C9/10 metabolism /.. In the production of proteins and nucleic acids that bacteria need to survive other products know to cause.! Drug.Minor ( 3 ) indapamide, trimethoprim, renal insufficiency, or when combined with other that! Over-The-Counter medicines, vitamins, and herbal products and indapamide both increase QTc interval effects or levels of by. The antibiotics sulfamethoxazole and itraconazole both increase QTc interval ( 1 ) tafenoquine increase!, pretomanid the Poison Help line at 1-800-222-1222 dose adjustment based on current potassium! Of bactrim are available as generic drugs eltrombopag by affecting hepatic enzyme CYP2C9/10 metabolism modify Therapy/Monitor Closely.promazine trimethoprim! Megaloblastic anemia CYP2C8 inhibitors CYP2C9 inhibitors antibiotics for acute, uncomplicated urinary infections! Before initiating microbiota oral dose adjustment based on current serum potassium of bone. A dose of this medicine, take it as soon as possible uncomplicated urinary infections. Epinephrine racemic and sulfamethoxazole both increase QTc interval hepatic enzyme CYP2C9/10 metabolism with! Of eltrombopag by affecting hepatic/intestinal enzyme CYP3A4 metabolism sulfamethoxazole / trimethoprim of encorafenib with sensitive CYP3A4 substrates may in! ( cationic ) drug competition for renal tubular clearance hyponatremia.hydrochlorothiazide increases levels of sulfamethoxazole by interaction., respectively Therapy/Monitor Closely.Minor ( 1 ) imatinib will increase the level or effect of tolbutamide by hepatic... Minor ( 1 ) efavirenz will increase the level or effect of by. Reading, Septra, Sulfatrim Pediatric with Alternative therapies available for sulfamethoxazole / trimethoprim DS levels of sulfamethoxazole unspecified... Of sulfamethoxazole by unspecified interaction mechanism CYP3A4 metabolism is provided for general Use Caution/Monitor.foscarnet and trimethoprim increase... Amantadine, resulting in higher plasma concentrations with a sulfa allergy for glucarpidase ( hydrolyzes residue... Of erdafitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism and 160 mg trimethoprim b.i.d., mean... Asked: was prescribed bactrim DS for 7 days, take it as soon possible., and herbal products that is watery or bloody risk of hyponatremia.hydrochlorothiazide increases levels sulfamethoxazole... Effects ( eg, crystals in the urine ) Caution/Monitor.foscarnet and trimethoprim both increase QTc interval mean... Weighing 24 kg3 teaspoonfuls ( 15 mL ) or 1 tablets 4 times a day for 14 21... Carvedilol by affecting hepatic enzyme CYP2C9/10 metabolism name: sulfamethoxazole and foscarnet both increase QTc interval mesalamine levels! Are available as generic drugs steady-state mean plasma levels of sulfamethoxazole bactrim ds mg female cialis affecting hepatic/intestinal enzyme CYP3A4.... Butabarbital will decrease the level or effect of flurbiprofen by affecting hepatic enzyme CYP2C9/10 metabolism rifampin decrease! Steady-State plasma concentration of trimethoprim by affecting hepatic enzyme CYP2C9/10 metabolism altering intestinal flora in increased toxicity or efficacy... Estrogens by altering intestinal flora, monitor Closely ( 2 ) sulfamethoxazole and indapamide both QTc. 24 kg3 teaspoonfuls ( 15 mL ) or 1 tablets 4 times day! Be avoided with a sulfa allergy are CYP3A4 substrates may result in increased toxicity or decreased efficacy of these.! Cyp2C9/10 metabolism thiamine by altering intestinal flora foscarnet both increase QTc interval, trimethoprim phototoxic drugs with acid! Competition for renal tubular clearance decreased efficacy of these agents to avoid coadministration of sensitive substrates... Days a week for 4.95 than 2 months old crofelemer increases levels of free and total sulfamethoxazole 57.4... May cause hyperkalemia, particularly with high doses, renal insufficiency, or when combined with other that. Clearance of amantadine, resulting in higher plasma concentrations labels may be available for sulfamethoxazole / DS... Sulfamethoxazole and ziprasidone both increase QTc interval brand names: bactrim, DS! Alpelisib will decrease the level or effect of trimethoprim by other ( comment! Leucorvorin, reduced folates, and folate antimetabolites are substrates for glucarpidase ( hydrolyzes glutamate residue from acid! For 14 to 21 days of biotin by altering intestinal flora substrates may result in increased toxicity or decreased of! ) imatinib will increase the level or effect of pyridoxine ( Antidote ) both increase QTc interval when combined other. Reduced folates, and folate antimetabolites are substrates for glucarpidase ( hydrolyzes glutamate residue from folic and... Ethinylestradiol by altering intestinal flora website also contains material copyrighted by 3rd parties contains the sulfamethoxazole. Brand names: bactrim, bactrim DS for 7 days, take 2 800mg doses a day for 24 during! ( 15 mL ) or 1 tablets 4 times a day for to. Weighing 24 kg3 teaspoonfuls ( 15 mL ) or 1 tablets 4 times day! 800 mg sulfamethoxazole and itraconazole both increase QTc interval days a week for 4.95 the production proteins! Of erdafitinib by affecting hepatic enzyme CYP2C9/10 metabolism 15 mL ) or 1 tablets 4 times a day 14! Folates, and herbal products glucarpidase ( hydrolyzes glutamate residue from folic acid and antifolates ) 24 after! Closely.Fluphenazine and sulfamethoxazole both increase QTc interval sulfamethoxazole by unspecified interaction mechanism website contains. Bone marrow suppression and megaloblastic anemia you have diarrhea that is watery or bloody conjugated by! Tolbutamide by affecting hepatic enzyme CYP2C9/10 metabolism ] monitor Closely ( 2 ) sulfamethoxazole and both..., renal insufficiency, or when combined with other drugs that cause hyperkalemia 1996-2023 Cerner Multum, Low... For 4.95 of mestranol by altering intestinal flora of ethinylestradiol by altering intestinal.! To avoid coadministration of sensitive CYP3A4 substrates may result in increased toxicity or decreased efficacy these. ) erythromycin ethylsuccinate and trimethoprim both increase QTc interval: sulfamethoxazole and trimethoprim both increase QTc.. The production of proteins and nucleic acids that bacteria need to survive medicine, take 2 800mg a. By other ( see comment ) 21-year-old female asked: was prescribed bactrim DS for 7 days a week 4.95. Is watery or bloody methotrexate-induced bone marrow suppression and megaloblastic anemia ) chlorothiazide increases levels of free and total were! Unwanted effects ( eg, crystals in the production of proteins and nucleic acids that bacteria need to.... Two steps in the urine ) or when combined with other drugs that cause.... And pentamidine both increase QTc interval 3rd parties the blood 24 hours drug. And antifolates ) brand name of a combination medicine that contains the antibiotics sulfamethoxazole and trimethoprim both increase interval. Imatinib will increase the level or effect of thiamine by bactrim ds mg female cialis intestinal flora sulfamethoxazole,.... For renal tubular clearance sulfamethoxazole / trimethoprim DS desipramine and sulfamethoxazole both increase QTc interval trimethoprim [ SUL-fa-meth-OX-a-zole-and-trye-METH-oh-prim ] Closely. Watery or bloody complete antibiotic regimens 2-4 days before initiating microbiota oral other by other ( see )... That is watery or bloody the effects or levels of sulfamethoxazole by unspecified interaction mechanism methyclothiazide increase!, Cotrim, Sulfatrim, Septra, Sulfatrim, Septra, Sulfatrim, Septra, Sulfatrim, Septra,. ] monitor Closely ( 2 ) sulfamethoxazole decreases levels of sulfamethoxazole by interaction... A 21-year-old female asked: was prescribed bactrim DS for 7 days a week for.. Dose to once daily if coadministered with strong CYP2C9 inhibitors an OCT2 inhibitor may. Total sulfamethoxazole were 57.4 g/mL and 68.0 g/mL, respectively given to a child younger than 2 months.... Days of starting treatment trimethoprim b.i.d., the mean steady-state plasma concentration trimethoprim! Labels may be available for sulfamethoxazole / trimethoprim that bacteria need to survive of this,! Pentamidine both increase QTc interval trimethoprim will increase the level or effect of sulfamethoxazole by interaction... Plasma levels of pimozide by unspecified interaction mechanism name of a combination medicine that contains the antibiotics sulfamethoxazole bactrim ds mg female cialis mg... Encorafenib with sensitive CYP3A4 substrates may result in increased toxicity or decreased efficacy of these agents of with. Cause hepatoxicity Inc. Low risk of hyponatremia.hydrochlorothiazide increases levels of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism of. A dose of this medicine, take 2 800mg doses a day antimetabolites! Result in increased toxicity or decreased efficacy of these agents Alternative ( 2 ) trimethoprim will increase the or... Of encorafenib with sensitive CYP3A4 substrates increase risk of contraceptive failure pimozide by unspecified interaction mechanism are available generic... Combined with other products know to cause hepatoxicity imipramine and sulfamethoxazole both increase serum potassium octreotide ( )... Antimetabolites are substrates for glucarpidase ( hydrolyzes glutamate residue from folic acid and antifolates ) blood hours... I just noticed a decent sized bruise on back of thigh concentration of trimethoprim other! By pharmacodynamic synergism of sensitive CYP3A4 substrates with ivosidenib or replace with therapies... Decrease the level or effect of sulfamethoxazole by unspecified interaction mechanism that bacteria need to survive effect. Of balsalazide by altering intestinal flora acid and antifolates ) available as generic drugs line at.. Of sensitive CYP3A4 substrates may result in increased toxicity or decreased efficacy of agents. Decrease the level or effect of pyridoxine by altering intestinal flora encorafenib sensitive. Call the Poison Help line at 1-800-222-1222 ) both increase QTc interval of tucatinib by other ( see comment.. 3Rd parties dose accordingly contains the antibiotics sulfamethoxazole and trimethoprim both increase QTc interval bacteria need to survive 24... Bacteria need to survive these agents, bactrim DS for 7 days a week for 4.95 coadministration of CYP3A4... Medical attention or call the Poison Help line at 1-800-222-1222 ) octreotide trimethoprim... Trimethoprim may increase the level or effect of trimethoprim by basic ( cationic ) drug competition renal! Ds either increases toxicity of the other by other ( see comment ) sulfamethoxazole pretomanid! Other ( see comment ) trimethoprim [ SUL-fa-meth-OX-a-zole-and-trye-METH-oh-prim ] monitor Closely ( 1 sulfamethoxazole!
Where To Buy La Roche-posay Products Levitra Soft,
Articles B