Use Caution/Monitor. Serious - Use Alternative (1)chloroquine increases toxicity of procainamide by QTc interval. Monitor Closely (1)phenytoin will decrease the level or effect of chloroquine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Immunosuppressive therapies, including irradiation, antimetabolites, alkylating agents, cytotoxic drugs, and corticosteroids (used in greater than physiologic doses), may reduce the immune responses to vaccines. Avoid or Use Alternate Drug. Minor/Significance Unknown. Avoid or Use Alternate Drug. Increases risk of torsades de pointes. Use Caution/Monitor. Print Save Chloroquine Dosage Medically reviewed by Drugs.com. Minor/Significance Unknown. omaveloxolone will decrease the level or effect of chloroquine by Other (see comment). Other (see comment). Remain indoors or in well-screened areas when possible. If coadministration is unavoidable, monitor patients for loss of therapeutic effect of these drugs. Tell your doctor right away if you have any serious side effects, including: slow heartbeat, symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), mental/mood changes (such as anxiety, depression, rare thoughts of suicide, hallucinations), hearing changes (such as ringing in the ears, hearing loss), easy bruising/bleeding, signs of liver disease (such as severe stomach/abdominal pain, yellowing eyes/skin, dark urine), signs of kidney problems (such as change in the amount of urine), muscle weakness, unwanted/uncontrolled movements (including tongue/face twitching), hair loss, hair/skin color changes. Monitor Closely (1)chloroquine increases levels of cyclosporine by decreasing metabolism. Avoid or Use Alternate Drug. chloroquine will increase the level or effect of doxepin by affecting hepatic enzyme CYP2D6 metabolism. Serious - Use Alternative (1)chloroquine increases toxicity of lumefantrine by QTc interval. Minor/Significance Unknown. cimetidine increases levels of chloroquine by decreasing metabolism. If it is near the time of the next dose, skip the missed dose. atomoxetine and chloroquine both increase QTc interval. Minor/Significance Unknown. Monitor Closely (1)lenacapavir will increase the level or effect of chloroquine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avloclor Tablets Active Ingredient: chloroquine phosphate Company: Alliance Pharmaceuticals See contact details ATC code: P01BA01 About Medicine Pharmacy Healthcare Professionals (SmPC) Patient Leaflet (PIL) This information is for use by healthcare professionals Last updated on emc: 07 Jul 2022 Quick Links chloroquine will increase the level or effect of oxymorphone by affecting hepatic enzyme CYP2D6 metabolism. Minor/Significance Unknown. Avoid or Use Alternate Drug. Use Caution/Monitor. For 2 weeks after abametapir application, avoid taking drugs that are CYP3A4 substrates. Modify Therapy/Monitor Closely. https://www.cdc.gov/malaria/travelers/drugs.html, FDA Revokes Emergency Use Authorization for Chloroquine and Hydroxychloroquine, https://emedicine.medscape.com/article/2500114-overview, https://www.medscape.com/resource/coronavirus). chloroquine increases toxicity of eribulin by QTc interval. Use Caution/Monitor. Avoid or Use Alternate Drug. efavirenz will decrease the level or effect of chloroquine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Consider dose reduction of sensitive CYP3A4 substrates. ChildrenUse and dose must be determined by your doctor. pimozide increases toxicity of chloroquine by QTc interval. Monitor Closely (1)chloroquine will increase the level or effect of benzhydrocodone/acetaminophen by affecting hepatic enzyme CYP2D6 metabolism. Minor/Significance Unknown. Monitor Closely (1)abiraterone increases levels of chloroquine by affecting hepatic enzyme CYP2D6 metabolism. Minor/Significance Unknown. Use Caution/Monitor. The risk for these side effects is increased with long-term use of this medication and with taking this medication in high doses. This medication may make you more sensitive to the sun. Minor/Significance Unknown. If not feasible, avoid use of abametapir. Serious - Use Alternative (1)chloroquine and lithium both increase QTc interval. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. This drug is usually started 1 to 2 weeks before entering the malarious area. Minor (1)chloroquine decreases effects of BCG vaccine live by pharmacodynamic antagonism. Serious - Use Alternative (1)chloroquine and midostaurin both increase QTc interval. If coadministration unavoidable, monitor for increased risk of QTc interval prolongation. Use Caution/Monitor. Use Caution/Monitor.Minor (1)chloroquine increases levels of tacrolimus by decreasing metabolism. phosphate (1:2) and has the following structural formula: C 18 H 26 CIN 3 .2H 3 PO 4 Molecular Weight: 515.86 Each tablet contains 250 mg of chloroquine phosphate USP . However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. Separate doses by at least 4 hr aluminum hydroxide will decrease the level or effect of chloroquine by Mechanism: inhibition of GI absorption. Monitor Closely (1)tobramycin inhaled and chloroquine both increase nephrotoxicity and/or ototoxicity. chloroquine increases toxicity of levofloxacin by QTc interval. chloroquine increases toxicity of ranolazine by QTc interval. Use Caution/Monitor. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Minor/Significance Unknown. You are being redirected to If inhibitor is discontinued, consider increase oliceridine dosage until stable drug effects are achieved. chloroquine will increase the level or effect of iloperidone by affecting hepatic enzyme CYP2D6 metabolism. Tell your doctor right away if you have symptoms of low blood sugar (see Side Effects section). Use Caution/Monitor. Use Caution/Monitor.Serious - Use Alternative (1)lopinavir will increase the level or effect of chloroquine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Consider dose reduction of sensitive CYP3A4 substrates. Serious - Use Alternative (1)chloroquine increases toxicity of arsenic trioxide by QTc interval. If you are taking this medication to prevent or treat malaria, use it for your current travel or condition only. Chloroquine phosphate tablet, USP, is a 4-aminoquinoline compound for oral administration. Use sunscreen and wear protective clothing when outdoors. Use Caution/Monitor. Minor (1)chloroquine decreases effects of diphtheria & tetanus toxoids/acellular pertussis/poliovirus, inactivated vaccine by pharmacodynamic antagonism. Minor/Significance Unknown. This medication may cause serious eye/vision problems. ECG monitoring is recommended if coadministered. Modify Therapy/Monitor Closely. Fexinidazole inhibits CYP3A4. Minor/Significance Unknown. CLINICAL PHARMACOLOGY chloroquine decreases effects of agalsidase alfa by pharmacodynamic antagonism. chloroquine increases toxicity of vorinostat by QTc interval. chloroquine increases toxicity of vemurafenib by QTc interval. Chloroquine is a prescription medication used to treat the symptoms of Malaria and Extraintestinal Amebiasis. Minor (1)chloroquine will increase the level or effect of galantamine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Stay at this 3-star business-friendly hotel in Montbard. Minor/Significance Unknown. Contraindicated. Applies only to oral form of both agents. Most chloroquine and oxaliplatin both increase QTc interval. provider for the most current information. Write a review. Elagolix is a weak-to-moderate CYP3A4 inducer. Minor/Significance Unknown. Avoid or Use Alternate Drug. Adjust dose of drugs that are CYP2D6 substrates as necessary. Immunosuppressive drugs may reduce the immune response to influenza vaccine. chloroquine and olaparib both increase pharmacodynamic synergism. chloroquine decreases effects of rabies vaccine chick embryo cell derived by pharmacodynamic antagonism. Use Caution/Monitor. belzutifan will decrease the level or effect of chloroquine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid coadministration of sensitive CYP2D6 substrates with givosiran. Monitor Closely (1)rolapitant will increase the level or effect of chloroquine by affecting hepatic enzyme CYP2D6 metabolism. Avoid or Use Alternate Drug. Use Caution/Monitor.Serious - Use Alternative (1)ribociclib and chloroquine both increase QTc interval. Use Caution/Monitor. Minor/Significance Unknown. Contraindicated.Minor (1)chloroquine increases toxicity of artemether/lumefantrine by QTc interval. Minor (1)acetazolamide will increase the level or effect of chloroquine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Use Caution/Monitor. Minor (1)chloroquine decreases effects of rotavirus oral vaccine, live by pharmacodynamic antagonism. Tell your doctor right away if you develop symptoms of low blood sugar, such as sudden sweating, shaking, hunger, blurred vision, dizziness, or tingling hands/feet. Do not store in the bathroom. Monitor Closely (1)chloroquine increases toxicity of vemurafenib by QTc interval. Use Caution/Monitor. Monitor Closely (1)chloroquine increases toxicity of ondansetron by QTc interval. Contraindicated. chloroquine increases levels of tamsulosin by affecting hepatic enzyme CYP2D6 metabolism. Avoid or Use Alternate Drug. Minor/Significance Unknown. Avoid or Use Alternate Drug.ceritinib will increase the level or effect of chloroquine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)chloroquine increases toxicity of escitalopram by QTc interval. Minor (2)chloroquine will increase the level or effect of promazine by affecting hepatic enzyme CYP2D6 metabolism. (See also Notes section.). Tell your doctor right away if you have symptoms of low blood sugar (see Side Effects section). Monitor Closely (1)goserelin increases toxicity of chloroquine by QTc interval. Serious - Use Alternative (1)chloroquine, mefloquine. Applies to the following strengths: 50 mg/mL; 500 mg; 250 mg Usual Adult Dose for: Malaria Prophylaxis Malaria Amebiasis Sarcoidosis Usual Pediatric Dose for: Malaria Prophylaxis Malaria Additional dosage information: Renal Dose Adjustments Use Caution/Monitor. chloroquine increases levels of trifluoperazine by decreasing metabolism. chloroquine increases levels of tacrolimus by decreasing metabolism. CLINICAL PHARMACOLOGY Modify Therapy/Monitor Closely. Use Caution/Monitor. Avoid or Use Alternate Drug. Use Caution/Monitor.Serious - Use Alternative (1)efavirenz and chloroquine both increase QTc interval. Adjust dose of drugs that are CYP3A4 substrates as necessary. Use Caution/Monitor.iloperidone increases levels of chloroquine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. 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