DESCOVY, the DESCOVY Logo, DESCOVY FOR PrEP, the DESCOVY FOR PrEP Logo, the DESCOVY Blue Pill Design, DAYTRACKER, TRUVADA, the TRUVADA Blue Pill Design, GSI, ADVANCING ACCESS, GILEAD, and the GILEAD Logo are trademarks of Gilead Sciences, Inc., or its related companies. These lists contain examples of serious side effects that can occur with Descovy or with both drugs (when taken individually). But for this use, it should not be taken by females at risk for. However, if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room. To help make sure you dont miss a dose, try setting a reminder on your phone. If youre taking Descovy to prevent HIV (as PrEP), missing doses raises your risk for contracting HIV. In comparison, 99.4% of people taking Truvada remained HIV free. Descovy should not be used for pre-exposure prophylaxis (PrEP) in patients with unknown or positive HIV-1 status. A boxed warning is the strongest warning the FDA requires. If youre taking Descovy to prevent getting HIV, the drug also stops the virus from entering your immune system. But researchers suggest that alcohol use is common in people with HIV. Below are details of how these medications are alike and different. A viral load of less than 200 copies/mL is considered viral suppression. With Descovy, youll take other HIV medications, too. Descovy is not meant to be used for HIV PrEP in females* who are at risk for contracting HIV through vaginal intercourse. There is no significant metabolism of emtricitabine. Its possible that some severe side effects of Descovy, such as liver damage, may also cause nausea. The effectiveness of Descovy in treating HIV has been shown in studies that tested peoples viral load. This is typically when a person is diagnosed with AIDS, the most severe stage of HIV. If youre taking Descovy for HIV treatment, your doctor might test how much HIV is in your body 2 to 8 weeks after starting or changing treatment. Drinking diluted juice or electrolyte drinks can help prevent dehydration from diarrhea. The FDA website provides several useful tips on medication disposal. Serious side effects and their symptoms can include: * Descovy has a boxed warning from the Food and Drug Administration (FDA) for this risk. Accessed April 20, 2022. https://www.cdc.gov/coronavirus/2019-ncov/hcp/pharmacies.html. Truvada (emtricitabine/ tenofovir disoproxil fumarate) is a medication used for Post-Exposure Prophylaxis, Pre-Exposure Prophylaxis and treatment for HIV-positive individuals. The UK is the first country to allow OTC access to Sanofi's tadalafil-based erectile dysfunction drug Cialis following a successful switch. Eventually, your CD4 cell count can decrease to dangerously low levels, putting you at risk for potentially fatal diseases (called opportunistic infections). This date is typically 1 year from the date they dispensed the medication. (Tenofovir alafenamide is one of the active drugs in Descovy.) Descovy may not be right for you if you have certain medical conditions or other factors that affect your health. Talk with your doctor about your health history before you take Descovy. Keep in mind, Descovy isnt recommended to prevent HIV in females* at risk for getting HIV from vaginal sex. Descovy and Truvada are HIV medications that contain similar active drugs. Your doctor may prescribe Descovy for pre-exposure prophylaxis (PrEP) of HIV. All other marks referenced herein are the property of their respective owners. After 48 weeks of Descovy treatment, the childrens CD4 cell counts were decreased by 0.6%. Descovy is used on its own for this purpose. Descovy is used to treat HIV in children weighing 35 kilograms (kg), which is about 77 pounds (lb), or more. Taking Descovy with both tipranavir (Aptivus) and ritonavir (Norvir), another combination of HIV drugs, can decrease levels of tenofovir alafenamide in your body. Descovy has boxed warnings about severe worsening of hepatitis B and HIV resistance. Truvada contains emtricitabine and tenofovir disoproxil fumarate. This helps prevent them from contracting HIV. To learn more about HIV and how Descovy is used for it, see the Is Descovy used for PrEP? and Is Descovy used for HIV? sections below. Descovy can interact with several types of drugs. Severe Interactions These medications are not usually taken. They can recommend ways to help you take your medication. This allows your immune system to fight off infection more effectively. Gilead Sciences, Inc. is providing this document to you, a US Healthcare Professional, in response to your unsolicited request for medical information. Its not clear if Descovy is associated with weight gain or not. You may have questions about Descovy and your treatment plan. However, studies have found both Descovy and Biktarvy to be effective for treating HIV. Be sure to follow your doctors instructions. Limitation of Use: DESCOVY FOR PrEP is not indicated in . See the Serious side effects section for more details on these side effects. Tap for Important Safety Information, including BOXED WARNING about the risk of drug resistance with DESCOVY FOR PrEP in undiagnosed early HIV-1 infection and post-treatment acute exacerbation of hepatitis B. The CD4 cell count is one way that doctors monitor your bodys response to medication. Children who weigh at least 35 kilograms (kg), which is about 77 pounds (lb) can take Descovy. Other serious side effects of Descovy may also cause fatigue. Sometimes people need to take medications to treat hepatitis after stopping Descovy. Counsel individuals on the importance ofdaily dosing, DESCOVY FOR PrEP must be prescribed only to individuals confirmed to be HIV negative, Drug-resistant HIV-1 variants have been identified with use of emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) for HIV-1 PrEP following undetected acute HIV-1, If screening or symptoms consistent with acute HIV-1 infection indicate an individual may have become HIV positive while taking DESCOVY FOR PrEP, convert the HIV-1 PrEP regimen to an HIV treatment regimen until HIV-negative status is confirmed, Test and monitor for chronic HBV and, if negative, consider vaccination, Individuals should strictly adhere to the recommended DESCOVY FOR PrEP dosing schedule, The effectiveness of DESCOVY FOR PrEP in reducing the risk of acquiring HIV-1 is strongly correlated with adherence, Some individuals, such as adolescents, may benefit from more frequent visits and counseling, DESCOVY FOR PrEP is not recommended in individuals with CrCl <30 mL/min, Assess serum creatinine, estimated CrCl, urine glucose, and urine protein prior to or when initiating, In individuals with chronic kidney disease, assess serum phosphorus, Severe acute exacerbations of hepatitis B have been reported in individuals infected with hepatitis B virus (HBV) who discontinued products containing FTC and/or TDF and may occur with discontinuation of DESCOVY, DESCOVY FOR PrEP is contraindicated in individuals with unknown or positive HIV status, Use DESCOVY FOR PrEP to reduce the risk of HIV-1 infection as part of a comprehensive strategy that includes adherence to daily dosing and safer sex practices, including condoms, to reduce the risk of sexually transmitted infections (STIs), Some HIV tests may not detect acute HIV infection. Please see Important Facts about DESCOVY for PrEP, including important warnings. This registry keeps track of reported pregnancy issues with Descovy. This is for adults and adolescents* who weigh at least . Missed doses. Examples of seizure drugs that can cause this interaction include: If you need to take a seizure medication with Descovy, your doctor may prescribe a seizure drug other than the ones listed above. Truvada. Descovy should be stored at room temperature (68F to 77F/20C to 25C) in its original container. * Descovy and Truvada have a boxed warning from the Food and Drug Administration (FDA) for this risk. Can I take Descovy to prevent HIV if I have vaginal sex? After 48 to 96 weeks of PrEP, 99.7% of people taking Descovy remained HIV free. In studies, diarrhea was the most common side effect reported in people who took Descovy to prevent HIV. For more information about this, see the Is Descovy used for PrEP? section directly above. DESCOVY for PrEP (pre-exposure prophylaxis) is a once-daily prescription medicine for adults and adolescents at risk of HIV. After 48 to 96 weeks of PrEP, there was no statistical difference found between Descovy and Truvada. Descovy contains two antiretroviral drugs (ARVs) combined in one tablet: emtricitabine (FTC, Emtriva) tenofovir alafenamide fumarate (tenofovir AF, TAF, Vemlidy) If HIV is not treated, your CD4 cell count will decrease. We will not use the information you provide for any additional purpose without your consent. Descovy contains two active drugs: emtricitabine and tenofovir alafenamide. Descovy is used to treat HIV in adults and in children who weigh at least at least 35 kilograms (kg), which is about 77 pounds (lb). For example, in an HIV treatment regimen, people can take Descovy with either: If youre taking Descovy for PrEP, youll likely take it without other HIV drugs. The information on this site is intended for audiences in the United States only. Also, Truvada is approved for use in females* at risk for getting HIV from vaginal sex. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Different interactions can cause different effects. We will review your responses, and if you are selected to move forward for consideration, we will contact you within 7-10 business days. However, there is a generic form of Truvada. adults with creatinine clearance below 15 . Preexposure prophylaxis for the prevention of HIV infection in the United States2021 update: a clinical practice guideline. However, be sure to take the dosage your doctor prescribes for you. Learn more. As with most drugs, some people can have an allergic reaction after taking Descovy. Ankylosing Spondylitis Pain: Fact or Fiction, Centers for Disease Control and Prevention (CDC), trading sex for money, drugs, shelter, or food, Descovy expiration, storage, and disposal. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. See additional information. They can help determine whats causing this symptom. 6. They can also determine if the diarrhea may be a symptom of HIV. Get tested for other STIs. Visit the Centers for Disease Control and Preventions Lets Stop HIV Together website to learn about how you can get tested for HIV, prevent HIV, and treat HIV. *, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat. In clinical studies of Descovy in children, the side effects were similar to those seen in adults. People taking Descovy to help prevent HIV, but who have undetected HIV, may develop HIV resistance to one or both of Descovys active drugs. Descovy is indicated in at-risk adults and adolescents weighing at least 35 kg for pre-exposure prophylaxis (PrEP) to reduce the risk of HIV-1 infection from sexual acquisition, excluding individuals at risk from receptive vaginal sex. Although both drugs contain emtricitabine, they contain different forms of tenofovir. Updated November 3, 2020. For more details about Descovys effectiveness in treating HIV, see the Descovy for HIV section. TAF is a newer pro-drug formulation that produces higher levels of the active drug (tenofovir diphosphate) in T-cells with smaller doses than TDF, which means lower concentrations in the blood and less drug exposure for the kidneys, bones and other organs. Of those taking Descovy, 99.7% of people remained HIV free. Severe worsening of hepatitis B. Certain foods may help ease diarrhea. 4 UNI | 4.95 per 1UNI. Learn here about how HIV can directly or indirectly cause joint pain and how people can diagnose and treat joint pain relating to HIV. If the patient misses a dose of Descovy within 18 hours of the time it is usually taken, the patient should take Descovy as soon as possible and resume the normal dosing schedule. There are currently no generic forms of either drug. Helps you get and maintain an erection when you need it. Taking Descovy with certain antibiotics is not recommended. How might bacteria-eating viruses and gut bacteria contribute to longevity? Resistance means the virus is less sensitive or doesnt respond to the drug. If you take too much Descovy, your doctor may closely monitor you for symptoms of overdose. (The immune system helps the body fight off infection and disease.). HIV-1-negative status must be confirmed immediately prior to initiation. Use of the term male in this article refers to sex assigned at birth. Descovy can be taken with or without food. * Sex and gender exist on spectrums. Do not use more Descovy than your doctor recommends. Talk with your doctor if your fatigue is affecting your quality of life. Dont stop taking Descovy if you have nausea. 14 kg to less than 25 kg (about 31 lb to less than 55 lb), their dosage is one 120-mg emtricitabine/15-mg tenofovir alafenamide tablet taken once per day. If you have diarrhea while taking Descovy, talk with your doctor about ways to manage this side effect. This recommendation is made to protect the health of both the pregnant person and the fetus. Once a person contracts HIV, the virus will attack certain cells in their immune system. Some may be a better fit for you than others. Taking only Descovy to treat HIV can make the virus more difficult to control, and resistance could develop. However, if you think youre having a medical emergency, you should call 911 or your local emergency number. Examples of such drugs that shouldnt be used for this age range (in combination with Descovy) include: In a clinical study, children ages 12 to 18 years old with HIV took Descovy with other HIV medications (elvitegravir and cobicistat). It helps lower the chances of getting HIV through sex. An HIV diagnosis may feel overwhelming, but new treatments are significantly reducing the effect that the virus has on quality of life. In these studies, researchers tested peoples HIV viral load, which is how many copies of HIV there are in 1 milliliter (mL) of blood. Once a person has contracted HIV, the virus will attack certain cells in their immune system. (This is considered one drink per day for females* or two drinks per day for males.*). The PrEP Provider Locator was developed by researchers from Emory University's Rollins School of Public Health with funding from MAC AIDS Fund. This list contains examples of serious side effects that can occur with both Descovy and Truvada (when taken individually). Side effects may differ based on whether youre using the drugs to treat or prevent HIV. Biktarvy contains three active drugs: emtricitabine, tenofovir alafenamide, and bictegravir. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. The information on this site is intended for audiences 18 years of age or older in the United States only. Descovy may not be right for you if you have certain medical conditions or other factors affecting your health. This lack of approval is because Descovy hasnt been tested for PrEP effectiveness in females who are at risk for HIV through vaginal intercourse. Descovy can be taken during pregnancy. These drugs prevent HIV from multiplying (making more virus). You should always consult your doctor or another healthcare professional before taking any medication. They have a reduced risk of transmitting HIV through pregnancy, breastfeeding, and shared needles. Brand-name medications usually cost more than generics. MNT is the registered trade mark of Healthline Media. Can I drink alcohol while taking Descovy? This drug has boxed warnings. This can make Descovy less effective for you. Certain medications can suppress (lower) your HIV blood levels to undetectable amounts, but its still not known if this means the virus has been completely eliminated. Descovy is also used to treat HIV in children who weigh at least 14 kg (about 31 lb) to less than 35 kg. It alerts doctors and patients about drug effects that may be dangerous. In clinical studies, adults who were new to HIV treatment took either Descovy or Truvada (a similar HIV medication). These lists contain examples of more common side effects that can occur with Biktarvy or with both drugs (when taken individually). Descovy and Truvada have some similar side effects and others that differ. This decrease in CD4 cell counts wasnt seen in children ages 12 to 18 years old who were new to HIV treatment. If you have concerns about your body weight while youre taking Descovy, talk with your doctor. Descovy generally costs less than Biktarvy. Descovy. DESCOVY for PrEP, the DESCOVY for PrEP Logo, the DESCOVY Blue Pill Design, DESCOVY, the DESCOVY Logo, TRUVADA FOR PrEP, the TRUVADA Blue Pill Design, TRUVADA, DAYTRACKER, ADVANCING ACCESS, GILEAD, the GILEAD Logo, and STEP UP. In animal studies, there were no harmful effects to the developing fetus seen when the pregnant animal received either of the active drugs in Descovy. Descovy is used for this purpose in adults and in children who weigh at least 14 kilograms (kg), which is about 31 lb, to less than 35 kg, which is about 77 pounds (lb). CD4 cells are white blood cells that help coordinate your immune systems response to infection. The usual recommended dosage for pre-exposure prophylaxis (PrEP) is 200-mg emtricitabine/25-mg tenofovir alafenamide tablet taken once a day. Descovy can cause mild or serious side effects. It alerts doctors and patients about drug effects that may be dangerous. Using many HIV drugs for treatment is called an HIV regimen. Possibly. For information about the difference between sex and gender, see this article. If you have severe kidney problems, you may not be able to take Descovy. Licensed by Artestar, New York. Its used in combination with other HIV drugs for this purpose. The active ingredients are emtricitabine and tenofovir alafenamide. Descovy contains the active drugs emtricitabine and tenofovir alafenamide. Think youre having a medical emergency, you should call 911 or your local descovy prep cialis professional! Of either drug conditions or other factors descovy prep cialis professional affect your health of hepatitis and! 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