In addition, they modify the bodys immune responses to diverse stimuli. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. If you are having a series of injections over a prolonged period, try not to miss an appointment. There may be decreased resistance and inability to localize infection when corticosteroids are used. As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy). Talk to your doctor about the risks and benefits of dexamethasone, especially if it is to be injected near your spine (epidural). This medication may interfere with certain lab tests (including skin tests), possibly causing false test results. It is sometimes used in combination with other medications to treat symptoms of low corticosteroid levels (lack of certain substances that are usually produced by the body and are needed for normal body functioning) and in the management of certain types of shock. It is unknown if this medication passes into breast milk. You should give an injectable stress dosing if your child: Is weak, unconscious or cannot wakeup easily. Shock unresponsive to conventional therapy if adrenocortical insufficiency exists or is suspected. Discuss the risks and benefits with your doctor. TaperDex 6-Day; TaperDex 7-Day; TopiDex; ZCORT 7-Day [DSC] Brand Names: Canada APO-Dexamethasone; Dexamethasone Omega Unidose; Dexamethasone-Omega; Odan-Dexamethasone; PMS-Dexamethasone; PMS-Dexamethasone Sod Phosphat [DSC] If you already have diabetes, check your blood sugar regularly as directed and share the results with your doctor. The initial dosage of dexamethasone sodium phosphate injection USP may vary from 0.50 mg/day to 9 mg/day depending on the specific disease entity being treated. This may not apply. Do not double the dose to catch up. Call for a new prescription if the date is near. Tell your doctor right away if you have any serious side effects, including: signs of infection (such as sore throat that doesn't go away, fever), bone/joint pain, fast/slow/irregular heartbeat, eye pain/pressure, vision problems, unusual weight gain, puffy face, swelling of the ankles/feet, symptoms of stomach/intestinal bleeding (such as stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds), mental/mood changes (such as depression, mood swings, agitation), menstrual period changes, muscle pain/cramps, weakness, easy bruising/bleeding, slow wound healing, thinning skin, seizures. Consult the product instructions and your pharmacist for storage details. 8 Both of these ranges fell outside of the accepted US Food and Drug Administration range for bioequivalence of 80% to 125%. 279 Princeton-Hightstown Rd. Call your doctor or health care professional to reschedule if you are unable to keep an appointment. 3. Keep it at room temperature. 1. Consult your doctor before breast- feeding. It is also important information to carry with you in case of emergencies. Made isotonic with sodium citrate. Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy, mineralocorticoid supplementation is of particular importance). Your doctor may attempt to reduce your dose slowly from time to time to minimize side effects. If you are going to need surgery or other procedures, tell your doctor or health care professional that you have taken this medicine within the last 12 months. Your doctor may also need to change your dose if you experience unusual stress on your body such as surgery, illness, or infection. Dexamethasone sodium phosphate injection USP is a sterile, clear, colorless solution, free from visible particles and a water-soluble inorganic ester of dexamethasone which produces a rapid response even when injected intramuscularly. Call your doctor for preventive treatment if you are exposed to chickenpox or measles. If after a reasonable period of time there is a lack of satisfactory clinical response, dexamethasone sodium phosphate injection USP should be discontinued and the patient transferred to other appropriate therapy. We comply with the HONcode standard for trustworthy health information. Drug-induced secondary adrenocortical insufficiency may be minimized by gradual reduction of dosage. Version: 5.01. A very serious allergic reaction to this drug is rare. This is not a complete list of possible side effects. People who use dexamethasone injection for a long time may develop glaucoma or cataracts. The initial dosage should be maintained or adjusted until a satisfactory response is noted. If you will be using dexamethasone injection at home, your healthcare provider will show you how to inject the medication. 5. Call your doctor for medical advice about side effects. [60760] Corticosteroids are given as adjunctive therapy to epinephrine. Report any new or worsening symptoms right away. What should I know about storage and disposal of this medication? DEXAMETHASONE (dex a METH a sone) is a corticosteroid. This medication may cause bone problems (osteoporosis) when used for an extended time. Talk to your doctor about the risks of using dexamethasone injection and how often you should have your eyes examined during your treatment. It decreases your immune system 's response to various diseases to reduce symptoms such as swelling and allergic-type reactions.This injectable form of dexamethasone is used when a similar drug. Dexamethasone injection is used to treat severe allergic reactions. Also tell them if you smoke, drink alcohol, or use illegal drugs. Report any new or worsening symptoms right away. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes. 5705185. Drug class: Glucocorticoids. Consult your pharmacist or local waste disposal company. Using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress. Inject air into the vial. A healthcare provider will give you this injection. Various dosage regimens have been used. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. 20 mg per 5 mL (4 mg / mL) Generic alternatives may be available. Information is also available online at https://www.poisonhelp.org/help. It is also used for other conditions, like blood disorders and diseases of the adrenal glands. WebMD Update: Dexamethasone, a steroid sometimes used for asthma, cancer, and rheumatoid arthritis, could reduce deaths in hospitalized coronavirus patients with severe complications by about a third, according to a new study. Older adults may be more sensitive to the side effects of this drug, especially bone loss/pain, stomach/intestinal bleeding, and mental/mood changes (such as confusion). . Studies have shown dexamethasone in single doses (0.3 mg/kg up to 1.7 mg/kg; maximum single dose 36 mg) or multiple doses (0.6 mg/kg once a day for 2 days) is comparable to a 5-day course of prednisone/prednisolone in the treatment of acute asthma exacerbations. Diagnostic testing of adrenocortical hyperfunction. Corticosteroids should be used cautiously in patients with ocular herpes simplex for fear of corneal perforation. Available for Android and iOS devices. A. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It works on the immune system to help relieve swelling, redness, itching, and allergic reactions. It is available in forms that can be taken by mouth, through a patch placed on the skin, as a cream, in eye drops, and as an injectable. The dosage is based on your medical condition and response to treatment. Neoplastic diseases. The liquid should be added to water, juice, soda or a soda-like beverage, applesauce, or pudding. Select a condition to view a list of medication options. Psychic derangements may appear when corticosteroids are used ranging from euphoria, insomnia, mood swings, personality changes, and severe depression to frank psychotic manifestations. Tell your doctor if your condition does not improve or if it worsens. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Dexamethasone tablets are also used in combination with other anti-myeloma products for the treatment of adults with multiple myeloma. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Properly discard this product when it is expired or no longer needed. If chickenpox develops, treatment with antiviral agents may be considered. Your doctor may attempt to reduce your dose slowly from time to time to minimize side effects. Ganglia require a dose of 1 to 2 mg. A dose of 0.4 to 1 mg is used for injection into tendon sheaths. Do not share this medicine with others. Stay away from people who are sick and wash your hands often while you are using this medication. Serious Neurologic Adverse Reactions with Epidural Administration. Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in: Acute noninfectious laryngeal edema (epinephrine is the drug of first choice). Stay away from anyone who has an infection that may easily spread (such as chickenpox, COVID-19, measles, flu). Dexamethasone sodium phosphate injection contains sodium sulfite, a sulfite that may cause allergic type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. Intravenous or intramuscular administration. Some conditions may become worse when this drug is suddenly stopped. Some conditions may become worse when this drug is suddenly stopped. Dexamethasone sodium phosphate injection USP is a sterile, clear, colorless solution, free from visible particles and is supplied as follows: Avoid receiving any other type of vaccine without your doctor's advice, including a yearly flu shot. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Last updated on May 14, 2023. Once opened, the solution is good for only 24 hours. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Serious side effects Other side effects Professional info FAQ Applies to dexamethasone: oral elixir, oral solution, oral tablet. Road construction around University Hospital, American Family Children's Hospital and University Station Clinic may result in travel delays and route changes.Read more. COMMON BRAND NAME(S): Decadron, DoubleDex, ReadySharp Dexamethasone, Simplist Dexamethasone, Solurex. Since adequate human reproduction studies have not been done with corticosteroids, use of these drugs in pregnancy, nursing mothers or women of childbearing potential requires that the possible benefits of the drug be weighed against the potential hazards to the mother and embryo or fetus. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. Talk to your doctor if you have been exposed to an infection or for more details. Common side effects of dexamethasone may include: fluid retention (swelling in your hands or ankles); acne, thinning skin, bruising or discoloration; changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist). If your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually 81-162 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Store your medication only as directed. Acute exacerbations of multiple sclerosis. 2. Keep all appointments with your doctor and the laboratory. No related drugs found for this medication. This may approximate 0.2 mg/kg/24 hours in divided doses. Drug interactions may change how your medications work or increase your risk for serious side effects. Things to remember when you fill your prescription. This regimen may be continued for several days postoperatively in patients requiring brain surgery. Aurobindo Pharma Limited It is used in the management of certain types of edema (fluid retention and swelling; excess fluid held in body tissues,) gastrointestinal disease, and certain types of arthritis. 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