Some people may have hair loss while taking divalproex. Before you have any medical tests, tell the medical doctor in charge that you are using this medicine. More likely to cause drowsiness in the elderly. Divalproex sodium does not relieve acute migraine headaches. Check with your doctor right away if you are having more than one of these symptoms: abdominal or stomach pain or tenderness, clay-colored stools, dark urine, decreased appetite, fever, headache, itching, loss of appetite, nausea and vomiting, skin rash, swelling of the feet or lower legs, unusual tiredness or weakness, or yellow eyes or skin. The insurance company will review the prior authorization request and decide if the drug will be covered. For short periods of time, such as when traveling, divalproex oral tablets may be stored at temperatures of 59F to 86F (15C to 30C). A single copy of these materials may be reprinted for noncommercial personal use only. Divalproex is FDA-approved to treat absence seizures, which are another type of seizure that can happen with epilepsy. Stay with the person until professional help arrives. Divalproex oral tablets are used to treat absence seizures that happen with or without other seizure types. 10. Swallow the sprinkle capsules whole. This article explores common epilepsy medications, their uses, and potential side effects. Divalproex is specifically used to treat complex partial seizures that happen with or without other seizure types. Divalproex (Depakote) is a first-choice medication to treat certain seizures, mania caused by bipolar disorder, and prevent migraines. Read and follow the instructions carefully. hair loss *. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Mental retardation with severe seizure disordersUse with caution. If youre concerned about feeling high after taking divalproex, talk with your doctor. There arent any herbs or supplements that have been specifically reported to interact with divalproex. Do not split, crush, or chew it. If you miss a dose of this medicine, take it as soon as possible. Your doctor will determine the best dosage to fit your needs. Divalproex may affect results of the following lab tests: Before getting any lab tests, be sure your doctor knows if youre taking divalproex. Generics tend to cost less than brand-name drugs. Financial assistance to help you pay for divalproex oral tablets may be available. A boxed warning is the most serious warning from the FDA. This may occur at any time during treatment and can quickly worsen. Other interactions can increase side effects or make them more severe. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Divalproex sodium may be used to treat certain types of seizure, to reduce mania in people with bipolar disorder, and as a preventive treatment for migraines. Divalproex may be used alone or with other antiepileptic drugs in adults and in children ages 10 years and older. The dosage for divalproex oral tablets your doctor prescribes will depend on several factors. Migraine is a condition that causes a severe headache along with other symptoms, such as: Divalproex oral tablets have been found to be effective for helping prevent migraine. Do not take other medicines unless they have been discussed with your doctor. Swallow the extended-release tablet or tablet whole with a full glass of water. It takes about four hours for divalproex sodium to reach maximum concentrations in the blood after a single dose. The sprinkle capsule gets its name from the fact that you can open the capsule and sprinkle it onto soft food. Symptoms of serious liver damage can include: Serious liver damage is more likely to happen in the first 6 months after you start taking divalproex. Epilepsy is a condition that causes repeated seizures, which happen because of abnormal electrical activity in the brain. Serious liver damage that can cause death, especially in children younger than 2 years old. May be taken with or without food; however, food may decrease the incidence of indigestion or stomach irritation. You can take divalproex with or without food. You can also call the American Association of Poison Control Centers at 800-222-1222 or use its online tool. If your dose is different, do not change it unless your doctor tells you to do so. What Are Dravet Syndrome & Lennox-Gastaut Syndrome? Investigating the power of music for dementia. Part of the medicine may pass into your stool after your body has absorbed the medicine. Divalproex sodium may not be suitable for everyone including those with depression or other mental illness, HIV or cytomegalovirus infection, liver disease, mitochondrial disorders, or urea cycle disorders. Swallow the tablet whole. Make sure you tell your doctor if you have any other medical problems, especially: Take this medicine exactly as directed by your doctor. For more information, see the Divalproex oral tablets and pregnancy section below. Side effects such as an increase in liver enzymes and thrombocytopenia (a decrease in platelet numbers in the blood) are more prevalent at higher dosages. Tell them about all prescription, over-the-counter, and other drugs you take. The following lists contain some of the key side effects that may occur while taking divalproex oral tablets. May be used to control manic episodes in people with bipolar disorder. May be effective for the prevention of migraine headaches in some people. Before taking divalproex sodium, tell your doctor or pharmacist if you are allergic to it; or to valproic acid or valproate sodium; or if you have any other allergies. Seek urgent medical advice. For more information about taking divalproex during pregnancy, see the Divalproex oral tablets and pregnancy section above. Divalproex oral tablets are FDA-approved to treat manic or mixed episodes related to bipolar disorder in adults. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If you dont have insurance, you can ask your doctor or pharmacist about online pharmacy options. Divalproex sodium may also be used for purposes not listed in this medication guide. Youll know more about how divalproex affects you after youve taken the drug for several days. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Consult your doctor for more details. So the drug should ease any symptoms of mania you may have, such as feeling high. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Ask your doctor if you have any questions. Ask your healthcare professional how you should dispose of any medicine you do not use. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect. Label: DIVALPROEX SODIUM capsule NDC Code (s): 55154-3552- Packager: Cardinal Health This is a repackaged label. Symptoms of absence seizures usually last less than 20 seconds and may include: Divalproex has been found to be effective for treating absence seizures. If you have insurance, youll also need to check whether your plan will cover Depakote or Depakote ER. Your doctor will adjust your dosage as needed if you take divalproex with other seizure drugs. Youll take divalproex oral tablets by mouth. Do not use more divalproex than your doctor recommends. High level of ammonia in your blood. Learn about the drugs side effects and how to. In rare cases, pancreatitis from divalproex may cause serious bleeding that leads to death. Divalproex is used to treat manic episodes or mixed episodes related tobipolar disorder. Chemically, it is known as sodium hydrogen bis (2-propylpentanoate). Take this medication by mouth as directed by your doctor. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Adults and children 10 years of age or olderDose is based on body weight and must be determined by your doctor. If you notice any of these side effects, tell your doctor right away. Batch CBD Full-Spectrum Gummies. Tell your doctor if you are pregnant or plan to become pregnant. This may help prevent worsening of seizures and reduce the possibility of withdrawal symptoms. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. bipolar I disorder with most recent episode mixed, a type of seizure disorder called tonic-clonic epilepsy, seizures with irregular muscle contractions, FDA Labeling for divalproex SODIUM on RxList. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. And before you start taking the drug, be sure to talk with them about all your health conditions. Drowsiness, dizziness, unsteadiness can increase the risk of falling. Does divalproex oral interact with other drugs you are taking? To learn more, visit their sites. Divalproex ER oral tablets can be used for both manic and mixed episodes related to bipolar disorder. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use divalproex sodium only for the indication prescribed. (Ammonia is a chemical your body produces when it breaks down protein.) Divalproex is FDA-approved for use in children ages 10 years and older. This drug may affect certain lab tests (such as urine ketones). Divalproex sodium may cause serious allergic reactions affecting multiple body organs (eg, liver or kidney). In Canada - Call your doctor for medical advice about side effects. Depakote, Depakote ER, Depakote Sprinkles. If youre a male using divalproex and have a sexual partner who can become pregnant, talk with your doctor about your birth control needs while using this drug. . Rarely, this medication has caused serious (sometimes fatal) liver problems, usually within the first 6 months of starting treatment. Your doctor may increase your dose as needed. For this purpose, divalproex may be used alone or with other antiepileptic drugs. At first, the usual dose is 10 to 15 milligrams (mg) per kilogram (kg) of body weight per day. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using divalproex. antibiotics such as clarithromycin, doxycycline, erythromycin, anticonvulsants such as lamotrigine, phenytoin, and phenobarbitone, antidepressants, such as desipramine, doxepin, isocarboxazid, nefazodone, phenelzine, or venlafaxine, antihistamines, such as azelastine, cetirizine, or levocetirizine, antipsychotics, such as aripiprazole, clozapine, haloperidol, or quetiapine, carbapenem antibiotics, such as ertapenem, imipenem, or meropenem, HIV medications such as indinavir and ritonavir, estrogen or progestin-containing oral contraceptives and hormonal treatments, medications that cause drowsiness, such as benzodiazepines, sedating antihistamines, and sleeping pills, opioid analgesics such as buprenorphine, codeine, fentanyl, oxycodone, and morphine, Divalproex [Package Insert]. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, pancreatitis, certain metabolic disorders (such as urea cycle disorders, Alpers-Huttenlocher syndrome), alcohol abuse, bleeding problems, brain disease (dementia), kidney disease, dehydration, poor nutrition. Enter your medication into the WebMD interaction checker. Youll start by taking 10 to 15 mg/kg* of body weight each day. This medicine is a pinkish-red, oval, enteric-coated, tablet imprinted with "D 84". Do not take this medicine if you have are suffering from impaired liver function. Different interactions can cause different effects. It is an anticonvulsant medicine used to treat bipolar disorder, epilepsy and seizures, and to prevent migraine headaches. But it may be best to avoid alcohol while taking divalproex. Children older than 2 years who might have these disorders should be closely monitored during treatment with divalproex sodium. WebMD does not provide medical advice, diagnosis or treatment. Generic name: Divalproex sodium Dosage form: tablet, film coated, extended release Drug class: Fatty acid derivative anticonvulsants Medically reviewed by Drugs.com. This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Last updated on Aug 17, 2022. Divalproex sodium is used to treat certain types of seizures (epilepsy). Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. For example, a person who weighs 50 kg (about 110 lb) would start by taking 750 mg of divalproex per day. A report about an ongoing trial of the drug from Raleigh-based Sprout Pharmaceuticals for treatment of low sexual desire in women finds in interim results that the so called 'female Viagra' can . However, the dose is usually not more than 60 mg per kg of body weight per day. If you miss a dose, take it as soon as you remember; however, do not double up a dose if it is almost time for the next dose. Drug interactions may change how your medications work or increase your risk for serious side effects. Women's health is once again the center of a political ping-pong match with evidence-based science on one side and anti-choice advocates on the other. Onto soft food should dispose of any medicine you do not split, crush, or it. Disorders should be closely monitored during treatment and can quickly worsen soon possible! 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