Minor/Significance Unknown. Use Caution/Monitor. Large dose of salicylate. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. Glimepiride is not used to treat type 1 diabetes. lornoxicam increases effects of glimepiride by unknown mechanism. Minor (1)gotu kola increases effects of glimepiride by pharmacodynamic synergism. Minor (1)sitagliptin, glimepiride. selegiline transdermal increases effects of glimepiride by unknown mechanism. Use Caution/Monitor. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. ziprasidone, glimepiride. You may report side effects to the FDA at 1-800-FDA-1088. Use Caution/Monitor. Coadministration of alogliptin with insulin and/or insulin secretagogues (eg, sulfonylureas, meglitinide derivatives) may increase risk for hypoglycemia; may require lower dose of insulin or insulin secretagogue . Monitor Closely (1)darunavir decreases effects of glimepiride by Other (see comment). Please read the Your use of this information means that you agree to the Terms of Use. Either increases effects of the other by pharmacodynamic synergism. vanadium increases effects of glimepiride by pharmacodynamic synergism. Minor (1)willow bark increases effects of glimepiride by plasma protein binding competition. Minor (1)potassium chloride increases effects of glimepiride by pharmacodynamic synergism. Use Caution/Monitor. Glimepiride stimulates the pancreas to produce more insulin. Non selective beta blockers may also mask the symptoms of hypoglycemia. Antidiabetic agents are often used in combination; dosage adjustments may be required when initiating or discontinuing antidiabetic agents. Other (see comment). Try to take it at the same time every day. Comment: Atypical antipsychotics have been associated with hyperglycemia that may alter blood glucose control; monitor glucose levels closely. Minor/Significance Unknown. You should not use glimepiride if you are allergic to it, or if you have: Glimepiride may increase your risk of serious heart problems, but not treating your diabetes can also damage your heart and other organs. Glimepiride works by stimulating the release of insulin from beta cells within the pancreas. Minor (1)methylprednisolone decreases effects of glimepiride by pharmacodynamic antagonism. Use Caution/Monitor. clotrimazole increases levels of glimepiride by decreasing metabolism. Large dose of salicylate. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Liver diseaseUse with caution. Ask your pharmacist about using those products safely. Thiazide dosage >50 mg/day may increase blood glucose. Monitor Closely (1)shark cartilage increases effects of glimepiride by pharmacodynamic synergism. Glimepiride is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Use Caution/Monitor. This medicine is a white, round, tablet imprinted with "30/2" and "4833G". glimepiride, insulin aspart. testosterone buccal system increases effects of glimepiride by pharmacodynamic synergism. Monitor Closely (1)exenatide injectable suspension, glimepiride. If your dose is different, do not change it unless your doctor tells you to do so. Monitor Closely (1)mecasermin increases effects of glimepiride by pharmacodynamic synergism. Ask your doctor if you have any questions. Properly discard this product when it is expired or no longer needed. Hypoglycemia risk increased. . Use Caution/Monitor. However, sulfonylureas (including glimepiride) cross the placenta and have been associated with neonatal adverse reactions such as hypoglycemia; therefore, therapy should be discontinued at least two weeks before expected delivery; poorly controlled diabetes in pregnancy is also associated with risks to mother and fetus, Breastfed infants of lactating women in therapy should be monitored for symptoms of hypoglycemia; not known whether drug is excreted in human milk and there are no data on effects of drug on milk production; drug is present in rat milk; developmental and health benefits of breastfeeding should be considered along with mother's clinical need for drug and any potential adverse effects on breastfed child from drug or from underlying maternal condition, Monitor breastfed infants for signs of hypoglycemia (e.g., jitters, cyanosis, apnea, hypothermia, excessive sleepiness, poor feeding, seizures). Do not double the dose to catch up. Avoid or Use Alternate Drug. Minor/Significance Unknown. Use Caution/Monitor. Risk of hypoglycemia. Use Caution/Monitor. semaglutide, glimepiride. Use Caution/Monitor. Serious - Use Alternative (1)aminolevulinic acid oral, glimepiride. Use Caution/Monitor. Use Caution/Monitor. indinavir decreases effects of glimepiride by Other (see comment). Minor (2)clonidine decreases effects of glimepiride by pharmacodynamic antagonism. Use Caution/Monitor. Comment: Reports of hyperglycemia due to insulin resistance with protease inhibitors. Talk to your doctor about the best way to treat low blood sugar. Keep all medical and lab appointments. Use Caution/Monitor. Minor/Significance Unknown. Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not be used by third parties without explicit permission. Use Caution/Monitor. imidapril increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Comment: Atypical antipsychotics have been associated with hyperglycemia that may alter blood glucose control; monitor glucose levels closely. . Some sulfonylureas may produce a disulfiram like rxn. Minor (1)eucalyptus increases effects of glimepiride by pharmacodynamic synergism. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Either increases effects of the other by pharmacodynamic synergism. Hypoglycemic effects may be increased. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. gymnema increases effects of glimepiride by pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. This medicine may increase your risk for bladder cancer if you take it for more than 12 months. Use Caution/Monitor. Additive hypoglycemic effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Caution if CYP2C9 substrate coadministered, particularly those with a narrow therapeutic index. Comment: Reports of hyperglycemia due to insulin resistance with protease inhibitors. sulfamethoxypyridazine increases effects of glimepiride by unspecified interaction mechanism. Use Caution/Monitor. choline magnesium trisalicylate increases effects of glimepiride by unknown mechanism. Use Caution/Monitor. The TraceGains knowledgebase does not contain every possible interaction. Risk of hypoglycemia. Antidiabetic agents are often used in combination; dosage adjustments may be required when initiating or discontinuing antidiabetic agents. Avoid concomitant use of inhibitors of the bile salt efflux pump (BSEP). Monitor Closely (1)clotrimazole increases levels of glimepiride by decreasing metabolism. Modify Therapy/Monitor Closely. Additive hypoglycemic effects. Modify Therapy/Monitor Closely. Monitor Closely (1)perindopril increases effects of glimepiride by pharmacodynamic synergism. glimepiride increases toxicity of cholic acid by decreasing elimination. Minor/Significance Unknown. Drug interactions may change how your medications work or increase your risk for serious side effects. Competitive inhibition of CYP2C9-mediated metabolism may also contribute to mechanism. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown. Use Caution/Monitor. Minor (1)methyltestosterone increases effects of glimepiride by pharmacodynamic synergism. Avoid coadministration of sensitive CYP2C9 substrates with ivosidenib or replace with alternate therapies. This is not a complete list of side effects and others may occur. 207 significant drug interactions. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Minor/Significance Unknown. Monitor Closely (1)atazanavir decreases effects of glimepiride by Other (see comment). Use alternatives if available. Minor/Significance Unknown. bexarotene increases effects of glimepiride by pharmacodynamic synergism. If this medication is used, it may be switched to insulin at least 2 weeks before the expected delivery date because of the medication's risk of causing low blood sugar in your newborn. Before using this medication, tell your doctor if you have heart failure. 180 minor drug interactions. Monitor Closely (1)glimepiride, dapagliflozin. gemifloxacin increases effects of glimepiride by pharmacodynamic synergism. glimepiride, cyclosporine. Drug Interactions Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. For non-prescription products, read the label or package ingredients carefully. Risk of hypoglycemia. Interaction especially seen in the treatment of hypokalemia. oxymetholone increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Use Caution/Monitor. Risk of hypoglycemia. Your dosage may need to be increased. You are being redirected to nabumetone increases effects of glimepiride by unknown mechanism. Either increases effects of the other by pharmacodynamic synergism. Do not use in larger or smaller amounts or for longer than recommended. Use Caution/Monitor. Hypoglycemia has not been associated with bexarotene monotherapy. Coadministration of photosensitizing drugs may enhance the phototoxic reaction to photodynamic therapy with aminolevulinic acid. Glimepiride is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. If you don't have these reliable forms of glucose, rapidly raise your blood sugar by eating a quick source of sugar such as table sugar, honey, or candy, or drink fruit juice or non-diet soda. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Avoid or Use Alternate Drug. Monitor Closely (1)tolfenamic acid increases effects of glimepiride by unknown mechanism. When patients are administered peginterferon alpha-2b with CYP2C9 substrates, the therapeutic effect of these drugs may be altered. How to Use Levitra Jelly 5. Minor/Significance Unknown. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Glimepiride is completely absorbed after oral administration within 1 hour of administration with a linear pharmacokinetics profile. This medicine is available only with your doctor's prescription. Minor (1)lycopus increases effects of glimepiride by pharmacodynamic synergism. Monitor blood glucose levels carefully. Coadministration of metreleptin with insulin and/or insulin secretagogues (eg, sulfonylureas, meglitinide derivatives) may increase risk for hypoglycemia; may require lower dose of insulin or insulin secretagogue. Minor/Significance Unknown. Thiazide dosage >50 mg/day may increase blood glucose. Ask your healthcare professional how you should dispose of any medicine you do not use. Monitor Closely (1)peginterferon alfa 2b decreases levels of glimepiride by affecting hepatic enzyme CYP2C9/10 metabolism. Monitor Closely (1)ofloxacin increases effects of glimepiride by pharmacodynamic synergism. If glimepiride is used, it may be switched to insulin at least 2 weeks before the expected delivery date because of glimepiride's risk of causing low blood sugar in your newborn. Colesevelam can decrease the absorption of glimepiride. Although not all of these side effects may occur, if they do occur they may need medical attention. Gatifloxacin is most likely to produce dysglycemia; moxifloxacin is least likely. Monitor Closely (1)ciprofloxacin increases effects of glimepiride by pharmacodynamic synergism. Monitor Closely (1)rucaparib will increase the level or effect of glimepiride by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor. Do not store in the bathroom. Gatifloxacin is most likely to produce dysglycemia; moxifloxacin is least likely. Other (see comment). Comment: Reports of hyperglycemia due to insulin resistance with protease inhibitors. It may cause mental confusion, headache, weakness, reddening of the face . Avoid drinking alcohol. Quinolone antibiotic administration may result in hyper- or hypoglycemia. This may occur if you do not consume enough calories from food or if you do unusually heavy exercise. aspirin rectal increases effects of glimepiride by unknown mechanism. Hyper and hypoglycemia have been reported in patients treated concomitantly with quinolones and antidiabetic agents. However, the dose is usually not more than pioglitazone 45 mg plus glimepiride 8 mg per day. Use Caution/Monitor. glimepiride, insulin inhaled. Monitor Closely (1)xipamide decreases levels of glimepiride by increasing renal clearance. Quinolone antibiotic administration may result in hyper- or hypoglycemia. Minor/Significance Unknown. Thiazide dosage >50 mg/day may increase blood glucose. Coadministration of insulin secretagogues with GLP-1 agonists may increase hypoglycemia risk. Monitor Closely (1)lonapegsomatropin decreases effects of glimepiride by Other (see comment). Consult your doctor because this may require a change in your treatment plan, medications, or blood sugar testing.This medication may make you more sensitive to the sun. Thiazide dosage >50 mg/day may increase blood glucose. Monitor Closely (1)glimepiride, insulin degludec. Large dose of salicylate. 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