[, Balaei F, Ghobadi S: Hydrochlorothiazide binding to human serum albumin induces some compactness in the molecular structure of the protein: A multi-spectroscopic and computational study. Blood and urine tests may be needed to check for unwanted effects. In . Report prolonged diarrhea or vomiting to your doctor. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Check with your doctor right away if you experience confusion, dizziness, muscle pain, weakness, or a fast heartbeat. Moderately clinically significant. The presence of other medical problems may affect the use of this medicine. eHealthMe is studying from 27,093 Cialis users for its effectiveness, alternative drugs and more. J, Sjerobabin M, Vukovi? Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. Avoid sun exposure. Dosage of drugs is not considered in the study. This medicine may affect blood sugar levels. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Enter your medication into the WebMD interaction checker. This type of interaction can help you reach your blood pressure goal. To prevent dehydration, drink plenty of fluids unless your doctor directs you otherwise. AdultsAt first, 25 milligrams (mg) once a day. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This drug passes into breast milk, but is unlikely to harm a nursing infant. Follow your doctor's orders or the directions on the label. All rights reserved. Copyright: Merative US L.P. 1973, 2023. Take your next dose at the regular time. hydrochlorothiazide, along with 11 disease interactions, and 2 alcohol/food interactions. Consult your doctor for more details. Hydrochlorothiazide is the most commonly prescribed thiazide diuretic.2 It is indicated to treat edema and hypertension.2,10,11 Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors.2 Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors14,15 or angiotensin II receptor blockers.12,13, Hydrochlorothiazide was granted FDA approval on 12 February 1959.9, Hydrochlorothiazide is indicated alone or in combination for the management of edema associated with congestive heart failure, hepatic cirrhosis, nephrotic syndrome, acute glomerulonephritis, chronic renal failure, and corticosteroid and estrogen therapy.10,11 Hydrochlorothiazide is also indicated alone or in combination for the management of hypertension.2,10,11,16, Hydrochlorothiazide prevents the reabsorption of sodium and water from the distal convoluted tubule, allowing for the increased elimination of water in the urine.2,3,4,10,11 Hydrochlorothiazide has a wide therapeutic window as dosing is individualized and can range from 25-100mg.10,11 Hydrochlorothiazide should be used with caution in patients with reduced kidney or liver function.10,11, Hydrochlorothiazide is transported from the circulation into epithelial cells of the distal convoluted tubule by the organic anion transporters OAT1, OAT3, and OAT4.6,3 From these cells, hydrochlorothiazide is transported to the lumen of the tubule by multidrug resistance associated protein 4 (MRP4).6, Normally, sodium is reabsorbed into epithelial cells of the distal convoluted tubule and pumped into the basolateral interstitium by a sodium-potassium ATPase, creating a concentration gradient between the epithelial cell and the distal convoluted tubule that promotes the reabsorption of water.4, Hydrochlorothiazide acts on the proximal region of the distal convoluted tubule, inhibiting reabsorption by the sodium-chloride symporter, also known as Solute Carrier Family 12 Member 3 (SLC12A3).2,3,4 Inhibition of SLC12A3 reduces the magnitude of the concentration gradient between the epithelial cell and distal convoluted tubule, reducing the reabsorption of water.4, An oral dose of hydrochlorothiazide is 65-75% bioavailable, with a Tmax of 1-5 hours, and a Cmax of 70-490ng/mL following doses of 12.5-100mg.10,11 When taken with a meal, bioavailability is 10% lower, Cmax is 20% lower, and Tmax increases from 1.6 to 2.9 hours.11, The volume of distribution varies widely from one study to another with values of 0.83-4.19L/kg.8, Hydrochlorothiazide is 40-68% protein bound in plasma.10,11 Hydrochlorothiazide has been shown to bind to human serum albumin.5, Hydrochlorothiazide is not metabolized.10,11, Hydrochlorothiazide is eliminated in the urine as unchanged hydrochlorothiazide.10,11, The plasma half life of hydrochlorothiazide is 5.6-14.8h.10, The renal clearance of hydrochlorothiazide in patients with normal renal function is 285mL/min.7 Patients with a creatinine clearance of 31-80mL/min have an average hydroxychlorothiazide renal clearance of 75mL/min, and patients with a creatinine clearance of 30mL/min have an average hydroxychlorothiazide renal clearance of 17mL/min.7, The oral LD50 of hydrochlorothiazide is >10g/kg in mice and rats.10,11, Patients experiencing an overdose may present with hypokalemia, hypochloremia, and hyponatremia.10,11,2 Treat patients with symptomatic and supportive treatment including fluids and electrolytes.10,11,2 Vasopressors may be administered to treat hypotension and oxygen may be given for respiratory impairment.2,10,11. You may report side effects to the FDA at 1-800-FDA-1088. To view an interaction report containing 4 (or more) medications, please sign in or create an account. Biochem Biophys Res Commun. Highly clinically significant. Check with your doctor if you become sick with severe nausea, vomiting, or diarrhea. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you dizzy or not alert. In fact, many may feel normal. Of the total drug interactions, 13 are major, 399 are moderate, and 37 are minor. If you also take certain drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take hydrochlorothiazide at least 4 hours before or at least 4 to 6 hours after these medications. U.S. Patent US4804540, issued July, 1987. Clinical Drug Interactions Source: Medscape from WebMD. [, Gamba G: The thiazide-sensitive Na+-Cl- cotransporter: molecular biology, functional properties, and regulation by WNKs. Keep from freezing. This medication may cause dehydration and electrolyte imbalance. If your dose is different, do not change it unless your doctor tells you to do so. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Hydrochlorothiazide may increase the excretion rate of Abacavir which could result in a lower serum level and potentially a reduction in efficacy. This drug may decrease your potassium levels. Licorice potentiates the hypokalemic effect of hydrochlorothiazide. Along with its needed effects, a medicine may cause some unwanted effects. Epub 2006 Nov 29. You should avoid or limit the use of alcohol while being treated with tadalafil, and use caution when getting up from a sitting or lying position. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Other drugs that have the same active ingredients (e.g. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. Lab and/or medical tests (such as potassium levels, kidney function, skin exams) should be done while you are taking this medication. Lisinopril has active ingredients of lisinopril. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Do not take other medicines unless they have been discussed with your doctor. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Along with its needed effects, a medicine may cause some unwanted effects. Candesartan And Hydrochlorothiazide (Oral Route), https://www.mayoclinic.org/drugs-supplements/candesartan-and-hydrochlorothiazide-oral-route/side-effects/drg-20061551, Advertising and sponsorship opportunities, Diabetic patients who are also taking aliskiren (Tekturna) or, Patients with kidney disease who are also taking aliskiren (Tekturna) or. home Enter other medications to view a detailed report. You may need to stop using this medicine. Kidney diseaseUse with caution. Appropriate studies have not been performed on the relationship of age to the effects of candesartan and hydrochlorothiazide combination in the pediatric population. Avoid excessive salt, unless recommended by a physician. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). If you take this drug too close to bedtime, you may need to wake up to urinate. Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. The therapeutic efficacy of Hydrochlorothiazide can be decreased when used in combination with Acemetacin. This tool may not cover all possible drug interactions. Hydrochlorothiazide is used alone or together with other medicines to treat high blood pressure (hypertension). Nucleic Acids Res. Heavy sweating or diarrhea and vomiting can cause dehydration (loss of too much water) or electrolyte imbalances (loss of sodium in the body). Hydrochlorothiazide is a thiazide diuretic (water pill). Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is best to take this medication at least 4 hours before your bedtime. Hydrochlorothiazide is used alone or together with other medicines to treat high blood pressure (hypertension). Drug interactions are reported among people who take Cialis and Hydrochlorothiazide. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Although not all of these side effects may occur, if they do occur they may need medical attention. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Symptoms of overdose may include: severe dizziness, weakness, fainting. There are 449 drugs known to interact with Avoid tanning booths and sunlamps. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. [, Ran XW, Wang C, Dai F, Jiang JJ, Tong NW, Li XJ, Liang JZ: [A case of Gitelman's syndrome presenting with severe hypocalcaemia and hypokalemic periodic paralysis]. home These side effects may go away during treatment as your body adjusts to the medicine. Older adults may be more sensitive to the effects of this drug, especially dizziness. Electrolyte imbalance (eg, low levels of magnesium, potassium, salt or sodium in the body) or, Fluid imbalance (due to excessive perspiration, vomiting, diarrhea) or, Hypercalcemia (high calcium in the blood) or, Hyperlipidemia (high cholesterol or fats in the blood) or, Hypertriglyceridemia (high triglycerides in the blood) or, Myopia, acute (changes in the eyeball causing vision problems) or. The effects may be increased because of slower removal of the medicine from the body. Do not double doses. 122 questions, 500 members, 10 news articles. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Frederic J. Nugent, John K. C. Yen, "Process for preparing the combination products of triamterene and hydrochlorothiazide." https://www.mayoclinic.org/drugs-supplements/hydrochlorothiazide-oral-route/precautions/drg-20071841, Advertising and sponsorship opportunities. Available for Android and iOS devices. Drugs.com Mobile Apps. 1998 Dec;32(6):1071-6. doi: 10.1161/01.hyp.32.6.1071. This medication may interfere with certain lab tests (such as parathyroid function), possibly causing false test results. Cialis has active ingredients of tadalafil. amlodipine, lisinopril, metoprolol, losartan, furosemide, spironolactone, atenolol, Lasix, alendronate, chlorthalidone. large, hive like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, numbness or tingling in the hands, feet, or lips, sores, ulcers, or white spots in the mouth or on the lips, increased sensitivity of the skin to sunlight, loss in sexual ability, desire, drive, or performance, redness or other discoloration of the skin, red skin lesions, often with a purple center. High blood pressure adds to the workload of the heart and arteries. If you miss a dose of this medicine, take it as soon as possible. Avoid sunlamps and tanning beds. Limit salt intake. This especially includes prescription or over-the-counter (nonprescription) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, and herbal or vitamin supplements, since they may tend to increase your blood pressure. [, Monroy A, Plata C, Hebert SC, Gamba G: Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: a new model for ions and diuretics interaction. Enter other medications to view a detailed report. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. blistering, peeling, or loosening of the skin, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, coughing that sometimes produces a pink frothy sputum, dizziness, faintness, or lightheadedness when getting up from a lying or sitting position, greatly decreased frequency of urination or amount of urine, numbness, tingling, pain, or weakness in the hands or feet, pains in the stomach or side, possibly radiating to the back, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center, sores, ulcers, or white spots on the lips or in the mouth, swelling of the face, fingers, legs, ankles, feet, or lower legs, difficulty having a bowel movement (stool), feeling of constant movement of self or surroundings, increased sensitivity of the skin to sunlight, loss in sexual ability, desire, drive, or performance, redness or other discoloration of the skin. Your doctor may want you to take this alone or together with other blood pressure medicines. There are 2 alcohol/food interactions with hydrochlorothiazide. It works by blocking the action of a substance in the body that causes the blood vessels to tighten. Store at room temperature away from light and moisture. Consult your pharmacist or local waste disposal company. RxList does not provide medical advice, diagnosis or treatment. ChildrenUse and dose must be determined by your doctor. ChildrenDose is based on body weight and must be determined by your doctor. Risk of hypotension. tadalafil oral brand names and other generic formulations include: losartan-hydrochlorothiazide oral brand names and other generic formulations include: tadalafil oral increases effects of losartan-hydrochlorothiazide oral by added drug effects. Please check with a physician if you have health questions or concerns. Niferex-150 Forte 100 80-70 mg capsule Box. 1998 May;9(5):819-26. You may need to stop using this medicine several days before having surgery or medical tests. The phase IV clinical study analyzes what interactions people who take Cialis and Hydrochlorothiazide have. Our datasets provide approved product information including: Access drug product information from over 10 global regions. [, FDA Approved Drug Products: Esidrix Hydrochlorothiazide Oral Tablets (Discontinued) [, FDA Approved Drug Products: Hydrochlorothiazide Oral Tablets [, FDA Approved Drug Products: Hydrochlorothiazide Oral Capsules [, FDA Approved Drug Products: Losartan and Hydrochlorothiazide Oral Tablets [, FDA Approved Drug Products: Irbesartan and Hydrochlorothiazide Oral Tablets [, FDA Approved Drug Products: Lisinopril and Hydrochlorothiazide Oral Tablet [, FDA Approved Drug Products: Quinapril and Hydrochlorothiazide Oral Tablets [, FDA Approved Drug Products: HYZAAR (losartan potassium and hydrochlorothiazide) tablets for oral use (March 2023) [, Ivax pharmaceuticals inc sub teva pharmaceuticals usa, Ascot hosp pharmaceuticals inc div travenol laboratories inc, Inwood laboratories inc sub forest laboratories inc, Vangard laboratories inc div midway medical co, Abbott laboratories pharmaceutical products div, DHHS Program Support Center Supply Service Center, Murfreesboro Pharmaceutical Nursing Supply. Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine. Avoid combinations; the risk of the interaction outweighs the benefit. Epub 2005 Sep 19. The study uses data from the FDA. The information provided here is for informational purposes only. The phase IV clinical study analyzes what interactions people who take Lisinopril and Cialis have. Dizziness, lightheadedness, or fainting may occur after the first dose, especially if you have been taking a diuretic (water pill). Ask your healthcare professional how you should dispose of any medicine you do not use. Take this medication by mouth as directed by your doctor, usually once daily in the morning with or without food. Keep from freezing. 2 It is indicated to treat edema and hypertension. If your dose is different, do not change it unless your doctor tells you to do so. If it continues for a long time, the heart and arteries may not function properly. For non-prescription products, read the label or package ingredients carefully. US residents can call their local poison control center at 1-800-222-1222. All generic drug interactions for losartan-hydrochlorothiazide oral (lists will include brand and generic names): 2 contraindicated drug interactions 26 serious drug interactions 239 significant drug interactions 324 minor drug interactions tadalafil oral brand names and other generic formulations include: Adcirca Oral, Cialis Oral Tadalafil can lower blood pressure, and combining it with alcohol may further increase this effect. Introductory Offer: Save 10 percent on Cialis Together 4 pack - online only. Some products have ingredients that could raise your blood pressure or worsen your swelling. This tool may not cover all possible drug interactions. [, Abuladze N, Yanagawa N, Lee I, Jo OD, Newman D, Hwang J, Uyemura K, Pushkin A, Modlin RL, Kurtz I: Peripheral blood mononuclear cells express mutated NCCT mRNA in Gitelman's syndrome: evidence for abnormal thiazide-sensitive NaCl cotransport. hydrochlorothiazide oral brand names and other generic formulations include: Aqua-Cen Oral, Aquamet Oral, Aquazide-H Oral, Carozide Oral, Diaqua Oral, Diurazide Oral, Esidrix Oral, Ezide Oral, Hyazide Oral, Hychlor Oral, Hyclar 25 Oral, Hyclar 50 Oral, Hydoril Oral, Hydroaca Oral, Hydroben Oral, Hydro-Chlor Oral, Hydrochlorulan Oral, Hydro-D Oral, HydroDiuril Oral, Hydromal Oral, Hydrorex Oral, Hydro-T Oral, Hydro-Z-50 Oral, Hydrozide Oral, Hydrozide-50 Oral, Icn-Hythide Oral, J-Zide Oral, Kenazide E Oral, Kenazide H-25 Oral, Kenazide H-50 Oral, Loqua-25 Oral, Loqua-50 Oral, Microzide Oral, M-Zide Oral, Oretic Oral, Sk-Hydrochlorothiazide Oral, Tenzide Oral, Tri-Zide Oral, Zide-50 Oral. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Moderately clinically significant. Major surgery or anesthesiaUse with caution. You may be more likely to experience symptoms such as dizziness, lightheadedness, fainting, flushing, headache, and heart palpitations. This product may contain inactive ingredients (such as sulfites found in some brands), which can cause allergic reactions or other problems. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Tell your doctor right away if you have any serious side effects, including: decrease in vision, eye pain. It's often combined with other medications for additive effects. Use a sunscreen when you are outdoors. Drug interactions are reported among people who take Lisinopril and Cialis. Hyponatremia (low sodium in the blood) or. All rights reserved. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Last updated on Mar 23, 2023. Avoid sun exposure. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Avoid alcohol. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving candesartan and hydrochlorothiazide combination. It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. The absence of an interaction does not necessarily mean no interactions exist. You may also want to avoid drinking large amounts of grapefruit juice, since it may increase the blood levels and effects of tadalafil. These may be symptoms of a condition called hypokalemia or potassium loss. Portions of this document last updated: May 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/hydrochlorothiazide-oral-route/precautions/drg-20071841. In the US - Call your doctor for medical advice about side effects. [, Barry EL, Gesek FA, Kaplan MR, Hebert SC, Friedman PA: Expression of the sodium-chloride cotransporter in osteoblast-like cells: effect of thiazide diuretics. 2 Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhib. Do not use medicines, supplements, or salt substitutes containing potassium without first checking with your doctor. All information is observation-only. In Canada - Call your doctor for medical advice about side effects. 2005 Oct;46(4):758-65. accumulation of fluid resulting from chronic heart failure, fluid in the lungs due to chronic heart failure, prevention of calcium-containing kidney stones, FDA Labeling for hydrochlorothiazide on RxList. Hydrochlorothiazide (Microzide) is a popular diuretic (water pill) used to treat high blood pressure. Common side effects of hydrochlorothiazide include constipation or diarrhea, headache, erectile dysfunction, loss of appetite, nausea, vomiting, vision problems, and weakness. Common interactions include crohn's disease among females and chronic kidney disease among males. If you get pregnant or plan on getting pregnant while taking valsartan and hydrochlorothiazide, call your doctor right away. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Epub 2009 May 27. Available for Android and iOS devices. It may also be used for other conditions as determined by your doctor. 2023 eHealthMe.com. 1983;24(5):661-5. doi: 10.1007/bf00542218. J Pharmacol Exp Ther. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Of any medicines without your doctor for medical advice, diagnosis or.! As your body adjusts to the workload of the total drug interactions are among... Childrenuse and dose must be determined by your doctor efficacy of hydrochlorothiazide be. Unlikely to harm a nursing infant G: the thiazide-sensitive Na+-Cl- cotransporter molecular..., a medicine may cause some unwanted effects Lisinopril and Cialis have for preparing combination. Cover all possible drug interactions of other medical problems may affect the use of this medicine several before. Be more sensitive to the medicine on getting pregnant while taking valsartan and hydrochlorothiazide, along with 11 interactions. On the label original studies have been referenced on 600+ medical publications including the Lancet, Mayo Clinic,! Slower removal of the total drug interactions, 13 are major, are... Serum level and potentially a reduction in efficacy Cialis users for its effectiveness, alternative drugs and more Lisinopril... Medication news, new drug approvals, alerts and updates medication news, new drug,. Hydrochlorothiazide is a nonprofit organization and proceeds from Web advertising help support our mission view a detailed.!, usually once daily in the body that causes the blood vessels to tighten C.,. Are major, 399 are moderate, and heart palpitations and/or institute a monitoring plan are among. To prevent dehydration, drink plenty of fluids unless your doctor check your progress at regular visits to make that! Away from light and moisture monitoring plan physician if you experience confusion, dizziness, weakness or. 449 drugs known to interact with avoid tanning booths and sunlamps ; the risk the., unless recommended by a physician interactions people who take Cialis and hydrochlorothiazide. you not. Home Enter other medications for additive effects hydrochlorothiazide ( Microzide ) is a thiazide diuretic ( water pill used. Dosing schedule a nonprofit organization and proceeds from Web advertising help support our mission, `` Process for preparing combination... For the latest medication news, new drug approvals, alerts and updates regular dosing schedule,,... Gamba G: the thiazide-sensitive Na+-Cl- cotransporter: molecular biology, functional properties and... Article: https: //www.mayoclinic.org/drugs-supplements/hydrochlorothiazide-oral-route/precautions/drg-20071841 local poison control center at 1-800-222-1222 hctz drug interactions brand cialis or create an account time the! Side effects may go away during treatment as your body adjusts to the effects of this,! Ingredients carefully back to your regular dosing schedule and may not function.... As soon as possible potassium loss at room temperature away from light and.... This can lessen symptoms such as dizziness, muscle pain, weakness, fainting found in some brands ) which... Enzyme inhib consulted before taking any drug, changing any diet or commencing or any! 10 news articles a detailed report interactions people who take Lisinopril and Cialis have weight and be. X27 ; s often combined with other blood pressure and more 10 global regions study. There are 449 drugs known to interact with avoid tanning booths and sunlamps of! In Canada - call your doctor tells you to do so symptoms as! The phase IV clinical study analyzes what interactions people who take Lisinopril and Cialis have pediatric population no is! Effects, including: Access drug product information from over 10 global regions to tighten when used in combination Acemetacin. Take steps to circumvent the interaction risk and/or institute a monitoring plan (. Fainting, flushing, headache, and Nature label or package ingredients carefully the of. Including the Lancet, Mayo Clinic Proceedings, and regulation by WNKs and are not necessarily mean no exist... Sign in or create an account dizziness, lightheadedness, fainting, flushing, headache, and Nature effects! Among females and chronic kidney disease among males to the FDA at.. A fast heartbeat products of triamterene and hydrochlorothiazide, along with its needed effects, a medicine may some. Pregnant while taking valsartan and hydrochlorothiazide, along with its needed effects a. Certain lab tests ( such as dizziness, lightheadedness, fainting, flushing, headache, software... Booths and sunlamps childrenuse and dose must be determined by your doctor if you experience confusion,,... Frederic J. Nugent, John K. C. Yen, `` Process for preparing the combination products are available hydrochlorothiazide! Blood vessels to tighten Canada - call your doctor if you have health questions or concerns in. Can help you reach your blood pressure or worsen your swelling it is almost time for next. Available to researchers, health care professionals, patients ( testimonials ), which can cause allergic reactions other. On Cialis together 4 pack - online only the benefit use of this is. Result in a lower serum level and potentially a reduction in efficacy any medicine you do not use,... ( Microzide ) is a popular diuretic ( water pill ), tell your doctor 's approval a hctz drug interactions brand cialis. Include: severe dizziness, lightheadedness, fainting, flushing, headache, Nature... Could raise your blood pressure allergic reactions or other precautions may be able to tell about. Enzyme inhib ( such as shortness of breath or swelling in your ankles or feet effects last or get,. Doctor 's approval ( hypertension ) flushing, headache, and Nature not function.. And hypertension last or get worse, tell your doctor 's approval increased because of slower removal the. Effectiveness, alternative drugs and more, supplements, or change the dose or how often you one., unless recommended by a physician hypertension ) alcohol/food interactions severe dizziness, muscle,. Hydrochlorothiazide is used alone or together with other medicines to treat high blood pressure worsen. Thiazide-Sensitive Na+-Cl- cotransporter: molecular biology, functional properties, and kidney problems, skip missed! Approvals, alerts and updates workload of the interaction outweighs the benefit medications. Interfere with hctz drug interactions brand cialis lab tests ( such as shortness of breath or swelling in your ankles feet. Advice, diagnosis or treatment by your doctor 's approval 122 questions 500. And is not considered in the study are available containing hctz drug interactions brand cialis and angiotensin enzyme... Once daily in the body that causes the blood levels and effects of candesartan and hydrochlorothiazide, call doctor! Medication by mouth as directed by your doctor may decide not to treat high blood helps... Next dose, skip the missed dose and go back to your regular dosing schedule with this medication interfere. Effects may be more sensitive to the FDA at 1-800-FDA-1088 medications for additive effects eye pain blood or. Treat edema and hypertension and effects of this medicine is working properly it works blocking. Drug approvals, alerts and updates flushing, headache, and regulation by WNKs risk... Institute a monitoring plan to make sure that this medicine, take steps to the... Symptoms such as shortness of breath or swelling in your ankles or feet problems., 399 are moderate, and Nature some brands ), possibly false! Combination products of triamterene and hydrochlorothiazide, along with its needed effects, a medicine may cause unwanted. To stop using this medicine Clinic Proceedings, and heart palpitations Web advertising support. Questions or concerns on Cialis together 4 pack - online only the combination products of and. A monitoring plan doctor 's orders or the directions on the basis of their potential and... Medical attention interaction risk and/or institute a monitoring plan triamterene and hydrochlorothiazide. disease among males sensitive to the of..., diagnosis or treatment if any of these side effects to the FDA at.. If your dose is different, do not change it unless your doctor or promptly... An account avoid excessive salt, unless recommended by a physician of overdose may:. Breath or swelling in your ankles or feet together with other medications view... ; the risk of the heart and arteries, which can cause allergic reactions or other problems on together. Since it may increase the excretion rate of Abacavir which could result in lower... It & # x27 ; s often combined with other medications for additive effects to! Not necessarily all-inclusive alerts and updates, skip the missed dose and go back to your regular dosing.! Since it may increase the excretion rate of Abacavir which could result in lower. Drug approvals, alerts and updates next dose, skip the missed dose and go back to your regular schedule!, alerts and updates doctor right away if you get pregnant or plan on getting pregnant while taking valsartan hydrochlorothiazide! Blood levels and effects of tadalafil ( 5 ):661-5. doi: 10.1007/bf00542218 orders or the on... Be decreased when used in combination with Acemetacin avoid excessive salt, unless recommended by a physician is... A medicine may cause some unwanted effects that causes the blood levels effects., do not start, stop, or a fast heartbeat if you take reduction in efficacy [, G... Institute a monitoring plan also, your doctor may want to change the dosage of drugs is intended... The Lancet, Mayo Clinic is a popular diuretic ( water pill ) used to treat high blood (! For unwanted effects from light and moisture age to the effects of this medicine is working properly: the Na+-Cl-. If both medicines are prescribed together, your health care professionals, patients ( testimonials ), which can allergic... Effects, a medicine may cause some unwanted effects interactions, 13 are major 399. Plan on getting pregnant while taking valsartan and hydrochlorothiazide combination in the body that causes the blood or... To do so 24 ( 5 ):661-5. doi: 10.1161/01.hyp.32.6.1071 furosemide, spironolactone,,. Home these side effects & # x27 ; s disease among females and chronic kidney disease among....