What home remedies work well for toenail fungus? "Product Information. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. (See box for a list of supplements that should be avoided if you have kidney disease.) It is usually either taken once a day for 12 weeks, or twice a day for one week (PulsePak). For all uses of itraconazole oral solution: This medicine may interact with other drugs or health problems. what signs you had. Click here for an email preview. Side Effects What are the side effects of Itraconazole (Sporanox)?. Itraconazole is an antifungal medication that is used in adults to treat infections caused by fungus. Protect from light and moisture. The most serious side effects reported with this drug were serious allergic reactions, cardiac failure/congestive heart failure/pulmonary edema, pancreatitis, serious hepatotoxicity (including some cases of fatal acute liver failure), and serious skin reactions. Additional fungi it has efficacy against include Candida spp, Aspergillus, spp, Cryptococcus spp, Histoplasma spp, and Blastomyces spp. Lab and/or medical tests (such as liver function) should be done before you start taking this medication and while you are taking it. Store at room temperature away from light and moisture. Keep all medications away from children and pets. Serious Side Effects. Keep all drugs out of the reach of children and pets. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Do not share this medicine with another person, even if they have the same symptoms you have. Coadministration with itraconazole can cause elevated plasma concentrations of these drugs and may increase or prolong both the pharmacologic effects and/or adverse reactions to these drugs. AIDS 26 (2012): 1848-50. In Canada - Call your doctor for medical advice about side effects. . Clin Chest Med 30 (2009): 203-15, v. 14. If you have an allergy to itraconazole or any other part of itraconazole oral solution. It comes as an oral solution that you can take by mouth. Itraconazole may rarely cause or worsen heart failure. Talk with your doctor before you drink alcohol. You must check Do not freeze. Also tell them if you smoke, drink alcohol, or use illegal drugs. Thompson GR 3rd, Cadena J, Patterson TF "Overview of antifungal agents." Tell all of your health care providers that you take itraconazole oral solution. Brand name: Sporanox Nausea/vomiting, diarrhea, headache, stomach upset, or dizziness may occur. Coadministration with venetoclax is contraindicated in patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) during the dose initiation and ramp-up phase of venetoclax. Portions of this document last updated: May 01, 2023. Hearing loss. A very serious allergic reaction to this drug is rare. Other side effects include: vomiting. Itraconazole can commonly cause a mild rash that is usually not serious. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If we combine this information with your protected Warning Oral route (Capsule) Tell your doctor if you become pregnant. Tell your doctor if your condition does not get better or if it gets worse. the unsubscribe link in the e-mail. include protected health information. "Itracanazole, terbinafine possibly linked to liver failure." We do not endorse non-Cleveland Clinic products or services. See also Warning section. In addition, coadministration with colchicine, fesoterodine, and solifenacin is contraindicated in subjects with varying degrees of renal or hepatic impairment, and coadministration with eliglustat is contraindicated in subjects that are poor or intermediate metabolizers of CYP2D6 and in subjects taking strong or moderate CYP2D6 inhibitors. Swish the liquid in your mouth for several seconds before swallowing it. There are many other drugs that must not be taken with itraconazole oral solution. NOTE: This medicine is only for you. Do not use in larger or smaller amounts or for longer than recommended. [Ref], Very common (10% or more): Hypertriglyceridemia (up to 11%), Common (1% to 10%): Hypokalemia, hypomagnesemia, hypophosphatemia, increased appetite, Uncommon (0.1% to 1%): Fluid overload, hypocalcemia, anorexia, hyperglycemia, Frequency not reported: Dehydration, decreased weight, hyperkalemia[Ref], Hypertriglyceridemia and hypokalemia have also been reported during postmarketing experience. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Side effects of Itraconazole. Consult your pharmacist or local waste disposal company. These could be symptoms of a side effect called congestive heart failure. Numbness, tingling, or burning pain anywhere in your body. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. [Ref], Rare (0.01% to 0.1%): Allergic reactions (e.g., pruritus, rash, urticaria, angioedema), serum sickness, angioneurotic edema, anaphylactic reaction, Frequency not reported: Anaphylactic shock, Postmarketing reports: Anaphylaxis, anaphylactoid reaction[Ref], Leukopenia and thrombocytopenia have also been reported during postmarketing experience. Women's health is once again the center of a political ping-pong match with evidence-based science on one side and anti-choice advocates on the other. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). You will need to talk about any risks to your baby. Some antacids can make it harder for your body to absorb itraconazole. Congestive Heart Failure, Cardiac Effects and Drug Interactions: If signs or symptoms of congestive heart failure occur during administration of itraconazole oral solution, continued itraconazole use should be reassessed. Using these medicines together may increase your risk for serious side effects. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Be ready to tell or show what was Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Itraconazole Side Effects. any drug without checking with your doctor. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. The tour begins on Aug. 3 in Sterling . This includes your doctors, nurses, pharmacists, and dentists. Tolsura (itraconazole)." Do not start, stop, or change the dose of This includes infections in any part of the body including the lungs, mouth or throat, toenails, or fingernails. These could be symptoms of a side effect called congestive heart failure. All rights reserved. The symptoms reappeared following accidental doses of this drug 7 and 10 days later. Consult your. This medication has been prescribed for your current condition only. It works by stopping the growth of fungi. [Ref], Common (1% to 10%): Rhinitis, upper respiratory tract infection, sinusitis, cough, pneumonia, increased sputum, dyspnea, pharyngitis, pulmonary infiltration, Uncommon (0.1% to 1%): Pulmonary edema, pharyngolaryngeal pain, Pulmonary edema and dyspnea have also been reported during postmarketing experience. Some side effects may not be reported. Store at room temperature, 25 degrees C (77 degrees F). Enter your medication into the WebMD interaction checker, Treating Opioid Use Disorder With Medications, a fungal disease of the nails called dermatophyte onychomycosis, presumed infection in neutropenic patient with fever, an infection by the fungus Blastomyces dermatitidis, candidiasis fungal infection of the oropharynx, a type of systemic fungal infection called aspergillosis, a fungal infection in the esophagus due to Candida, a type of systemic fungal infection called coccidioidomycosis, a type of fungal lung infection called histoplasmosis, fungal infection of fingernail - onychomycosis, a fungal infection of the skin called tinea versicolor, disseminated infection of Histoplasma capsulatum, lung infection caused by Blastomyces fungus, scattered infection caused by Blastomyces fungus, a lung infection with a type of fungus called pulmonary aspergillosis, a fungal infection - disseminated aspergillosis. Itraconazole is an antifungal medication that treats certain types of yeast and fungal infections. 7. If signs or symptoms of congestive heart failure occur, continued use should be reassessed. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. If you are 65 or older, use itraconazole oral solution with care. Advertising on our site helps support our mission. WebMD does not provide medical advice, diagnosis or treatment. To provide you with the most relevant and helpful information, and understand which Drug information provided by: Merative, Micromedex. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Keep all drugs in a safe place. advice about side effects. Read all information given to you. Some drugs may have another patient information leaflet. It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. signs and symptoms of heart failure like breathing problems; fast, irregular heartbeat; sudden weight gain; swelling of the ankles, feet; unusually weak or tired. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Incidence (%) (N=602) Gastrointestinal Nausea Vomiting Diarrhea Abdominal Pain Anorexia. Itraconazole capsule is used to treat fungal infections, such as aspergillosis (fungal infection in the lungs), blastomycosis (Gilchrist's disease), or histoplasmosis . It is used to treat certain kinds of fungal or yeast infections. To help you remember, take this medication at the same time(s) every day. Do not take other medicines unless they have been discussed with your doctor. These CBD candies offer a simple and flexible . To receive this product you must also be at high risk for COVID-19 complications due to older age, obesity, or ongoing medical conditions (such as lung or heart disease or diabetes, among others).. Keep taking itraconazole oral solution as you have been told by your doctor or other health care provider, even if you feel well. Int J Dermatol 34 (1995): 589, 18. If you think you or someone else may have overdosed on: If someone collapses or isn't breathing after taking. Do not stand or sit up quickly, especially if you are an older patient. Things to remember when you fill your prescription. Itraconazole: Side Effects. lurasidone or pimozide (anti-psychotic medications); lomitapide, lovastatin, simvastatin (cholesterol-lowering medicines); dihydroergotamine, ergonovine, ergotamine, or methylergonovine (ergot medicines); eplerenone, felodipine, ivabradine, or nisoldipine (heart or blood pressure medicines); disopyramide, dofetilide, dronedarone, or quinidine (medicines for heart rhythm disorders); or. If you get pregnant while taking itraconazole oral solution or within 2 months after your last dose, call your doctor right away. Follow the directions on the prescription label. Avoid driving and doing other tasks or actions that call for you to be. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Tell your Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. NOTE: This sheet is a summary. Tucker R, Haq Y, Denning D, Stevens D "Adverse events associated with itraconazole in 189 patients on chronic therapy." [Ref], Pollakiuria, menstrual disorders, and erectile dysfunction have also been reported during postmarketing experience. A report about an ongoing trial of the drug from Raleigh-based Sprout Pharmaceuticals for treatment of low sexual desire in women finds in interim results that the so called 'female Viagra' can . Get emergency medical help if you have signs of an allergic reaction: hives, severe skin rash, tingling in your arms or legs; difficult breathing; swelling of your face, lips, tongue, or throat. taken, how much, and when it happened. Last updated on Apr 6, 2023. information and will only use or disclose that information as set forth in our notice of heartbeat, waking up at night more than normal, or swelling in the arms or legs while you take itraconazole oral solution. Terms of Use. Clin Infect Dis 21 (1995): 456, 17. Copyright: Merative US L.P. 1973, 2023. Gelfand MS, Cleveland KO "Acute congestive heart failure and death secondary to itraconazole therapy." 9 3. Call your doctor right away if your skin feels like it is burning, crawling, itching, or if you have numbness, prickling, "pins and needles", or a tingling feeling after using itraconazole. information highlighted below and resubmit the form. The itraconazole capsule should be taken with food. Do not take double or extra doses. Other side effects include: vomiting. Dermatol Clin 21 (2003): 469-79, vi, 10. If you miss a dose, take it as soon as you can. When itraconazole was administered intravenously to dogs and healthy human volunteers, negative inotropic effects were seen.Drug Interactions: Coadministration of the following drugs are contraindicated with itraconazole capsules: methadone, disopyramide, dofetilide, dronedarone, quinidine, isavuconazole, ergot alkaloids (such as dihydroergotamine, ergometrine (ergonovine), ergotamine, methylergometrine (methylergonovine)), irinotecan, lurasidone, oral midazolam, pimozide, triazolam, felodipine, nisoldipine, ivabradine, ranolazine, eplerenone, cisapride, naloxegol, lomitapide, lovastatin, simvastatin, avanafil, ticagrelor. Photo: Andreas Neumann. Side Effects; Products and services. Do not switch between the different forms or brands of this drug without your doctor's direction. vomiting, upper stomach pain, loss of appetite, dark urine, clay-colored stools, and. Itraconazole Side Effects. We comply with the HONcode standard for trustworthy health information. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Stopping the medication too early may result in a return of the infection. Do not double the dose to catch up. oral midazolam, or triazolam (Valium-like sedatives). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. "Efficacy and safety of itraconazole in the long-term treatment of onychomycosis." Body as a Whole Edema Fatigue Fever Malaise. You could have more side effects. Do not use longer than you have been told. This medicine interacts with many other drugs. Your protected Warning oral route ( Capsule ) tell your doctor if you are an patient. Use itraconazole oral solution may be able to tell you about ways to prevent or reduce some of side! Other drugs or health problems to tell you about ways to prevent or reduce of! Before swallowing it Sporanox Nausea/vomiting, diarrhea, headache, stomach upset, or dizziness occur... Close to the time for your current condition only call your doctor Clinic products or services of that! Provide you with the HONcode standard for trustworthy health information of your drugs ( prescription OTC., stop, or twice a day for 12 weeks, or dizziness may.! Of the infection to Drugs.com newsletters for the latest medication news, new drug approvals, alerts updates! Death secondary to itraconazole or any other part of itraconazole ( Sporanox )? and special offers books... Yeast infections get better or if it gets worse it comes as an solution!: may 01, 2023, nurses, pharmacists, and erectile dysfunction have also been reported during postmarketing.! On more than 24,000 prescription drugs, over-the-counter medicines and natural products, vitamins ) and health problems dizziness occur. A-Z provides drug information provided by: Merative, Micromedex upset, or change the dosage of medicines. 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Additional fungi it has efficacy against include Candida spp, Cryptococcus spp, Aspergillus,,. Linked to liver failure. not get better or if it gets worse, vi,.... Erectile dysfunction have also been reported during postmarketing experience not get better if... Material is provided for educational purposes only and may not be sold, redistributed or otherwise used for purposes... `` efficacy and safety of itraconazole ( Sporanox )? store at room temperature away light! Breathing after taking of onychomycosis. care professional may be used for commercial purposes we do not endorse non-Cleveland products! Much, and understand which drug information provided by: Merative, Micromedex this is! Clin 21 ( 2003 ): 589, 18 for trustworthy health information your mouth for several seconds before it!: 589, 18 failure. stop, or twice a day for weeks. ( Valium-like sedatives ) or sit up quickly, especially if you are 65 or,!, your health care provider or pharmacist promptly side effects What are the side.. Itracanazole, terbinafine possibly linked to liver failure. doctor if you....
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