levoketoconazole will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor. These agents should only be combined if alternative treatment options are inadequate. loratadine will increase the level or effect of vincristine by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor.Minor (1)ketoconazole will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. azithromycin will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. Monitor therapy, Pramlintide: May enhance the anticholinergic effect of Anticholinergic Agents. Either increases effects of the other by Other (see comment). Serious - Use Alternative (1)clarithromycin will increase the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Nasal corticosteroids (e.g. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor. Avoid or Use Alternate Drug.Minor (1)clarithromycin will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. Properly discard this product when it is expired or no longer needed. ChildrenUse and dose must be determined by your doctor. Monitor Closely (1)elagolix will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Use Caution/Monitor. Monitor Closely (1)loratadine will increase the level or effect of risperidone by P-glycoprotein (MDR1) efflux transporter. This document does not contain all possible drug interactions. Avoid combination, Thiazide and Thiazide-Like Diuretics: Anticholinergic Agents may increase the serum concentration of Thiazide and Thiazide-Like Diuretics. May exacerbate accumulation of conjugated bile salts in the liver and result in clinical symptoms. Monitor therapy, Lasmiditan: May increase the serum concentration of P-glycoprotein/ABCB1 Substrates. Approximately one in five people experience urticaria (commonly referred to as hives) at some stage in their life. avapritinib and loratadine both increase sedation. Minor (1)felodipine will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. Chronic idiopathic urticaria: Limited data available (Kliegman 2011; Simons 1994): May be administered without regard to meals. It is also used to relieve itching from hives.Loratadine does not prevent hives or prevent/treat a serious allergic reaction (anaphylaxis). You are fully responsible for paying your prescriptions at the pharmacy at the time of service, but you will be entitled to receive a discount from the pharmacy in accordance with the specific pre-negotiated discounted rate schedule. Monitor Closely (2)nilotinib will increase the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.nilotinib will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. If you took 20 pills you better get a friend, call ambulance and get seen at ER fa. Monitor Closely (1)letermovir increases levels of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. MISSED DOSE: If you miss a dose, take it as soon as you remember. Minor/Significance Unknown. If you miss a dose of this medicine, take it as soon as possible. These agents should only be combined if alternative treatment options are inadequate. Consider therapy modification, Orphenadrine: CNS Depressants may enhance the CNS depressant effect of Orphenadrine. isocarboxazid increases effects of loratadine by Other (see comment). Monitor therapy, Nabilone: May enhance the CNS depressant effect of CNS Depressants. fosphenytoin will decrease the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. nilotinib will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. Larger doses of hyaluronidase may be required. Use Caution/Monitor. Review our medical disclaimer. Avoid combination, Alcohol (Ethyl): CNS Depressants may enhance the CNS depressant effect of Alcohol (Ethyl). While not FDA-approved for children younger than 2 years, the liquid formulation is sometimes prescribed by a doctor for younger children. loratadine will increase the level or effect of estradiol by P-glycoprotein (MDR1) efflux transporter. Monitor Closely (1)loratadine will increase the level or effect of paromomycin by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor. Monitor Closely (1)lonafarnib will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. buprenorphine subdermal implant and loratadine both increase sedation. Use Caution/Monitor. Consult your pharmacist or local waste disposal company. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Any product that is 5 mg can be taken twice a day. Loratadine continues to have an effect for at least 24 hours, regardless of whether a 24-hour or 12-hour product is used. Avoid or Use Alternate Drug. Monitor Closely (1)loratadine will increase the level or effect of amitriptyline by P-glycoprotein (MDR1) efflux transporter. amiodarone will increase the level or effect of loratadine by affecting hepatic enzyme CYP2D6 metabolism. Tablets: 10 mg Chewable tablets: 5 mg Orally disintegrating tablets: 5 mg, 10 mg Liquid: 1 mg/ mL Loratadine dosage for adults Loratadine is approved for use in adults to control allergy symptoms and urticaria. Use Caution/Monitor. loratadine will increase the level or effect of paliperidone by P-glycoprotein (MDR1) efflux transporter. Cromolyn nasal spray). Use Caution/Monitor. Monitor Closely (1)fostamatinib will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. A histamine skin test may be used to assess persistent antihistaminic effects. Do not increase your dose or take this drug more often than directed. Use Caution/Monitor. Modify Therapy/Monitor Closely. RELATED: Taking allergy medicine while pregnant. There are no withdrawal symptoms after stopping loratadine, so it is safe to discontinue use at any time if no longer needed. amiodarone will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. Serious - Use Alternative (1)sotorasib will decrease the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. Modify Therapy/Monitor Closely. If concomitant use is necessary, monitor serum transaminases and bilirubin. bosutinib increases levels of loratadine by P-glycoprotein (MDR1) efflux transporter. Minor/Significance Unknown. If not, is there a liquid Can you crush Voltaren? loratadine will increase the level or effect of loperamide by P-glycoprotein (MDR1) efflux transporter. More mild overdose symptoms may include headache, drowsiness, difficulty urinating, and fast heart rate. Monitor Closely (1)pregabalin, loratadine. Use Caution/Monitor. The range of prescription discounts provided under this discount plan will vary depending on the prescription and pharmacy where the prescription is purchased and can be up to 80% off the cash price. loratadine will increase the level or effect of nilotinib by P-glycoprotein (MDR1) efflux transporter. Avoid or Use Alternate Drug. Monitor Closely (2)hydrocortisone will decrease the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Last updated February 8, 2020. Use Caution/Monitor. Serious - Use Alternative (1)rifabutin will decrease the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Options include: Both of the above options can help better control your allergy symptoms. Minor/Significance Unknown. Monitor therapy, Cannabis: May enhance the CNS depressant effect of CNS Depressants. Use Caution/Monitor. Descriptions Loratadine is used to treat allergy symptoms, including runny or stuffy nose, sneezing, watery eyes, and itching of the eyes, nose or throat. conivaptan will increase the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Comment: Amifampridine can cause seizures. fludrocortisone will decrease the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If not, is there a liquid form of Voltaren? Discuss the risks and benefits with your doctor before taking this drug.This medication passes into breast milk. Monitor Closely (1)ivacaftor increases levels of loratadine by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor. Benzyl alcohol and derivatives: Some dosage forms may contain sodium benzoate/benzoic acid; benzoic acid (benzoate) is a metabolite of benzyl alcohol; large amounts of benzyl alcohol (99 mg/kg/day) have been associated with a potentially fatal toxicity (gasping syndrome) in neonates; the gasping syndrome consists of metabolic acidosis, respiratory distress, gasping respirations, CNS dysfunction (including convulsions, intracranial hemorrhage), hypotension, and cardiovascular collapse (AAP ["Inactive" 1997]; CDC, 1982); some data suggests that benzoate displaces bilirubin from protein binding sites (Ahlfors, 2001); avoid or use dosage forms containing benzyl alcohol derivative with caution in neonates. Monitor therapy, Amiodarone: May increase the serum concentration of Loratadine. Loratadine is a second-generation antihistamine that is used in a variety of conditions such as watery eyes, runny nose, sneezing, and pruritus. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Orally disintegrating tablets are placed on the tongue and dissolve rapidly. Discontinue anticholinergic agents at least 5 half-lives prior to administration of secretin. Use Caution/Monitor. celecoxib will increase the level or effect of loratadine by affecting hepatic enzyme CYP2D6 metabolism. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor Closely (1)loratadine will increase the level or effect of digoxin by P-glycoprotein (MDR1) efflux transporter. Minor/Significance Unknown. It can be given once or twice daily. Use Caution/Monitor. Use Caution/Monitor. indinavir will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. Monitor for toxicities of P-gp substrates that may require dosage reduction when coadministered with P-gp inhibitors. Use Caution/Monitor. brexpiprazole and loratadine both increase sedation. Use Caution/Monitor. Minor (1)haloperidol will increase the level or effect of loratadine by affecting hepatic enzyme CYP2D6 metabolism. Specifically, the risk of gastrointestinal adverse effects may be increased. Consider reducing dose when used concomitantly with lomitapide. feeling lightheaded. loratadine increases toxicity of cholic acid by decreasing elimination. Monitor therapy, Pitolisant: Antihistamines may diminish the therapeutic effect of Pitolisant. erythromycin base will increase the level or effect of loratadine by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor.Minor (2)ritonavir will increase the level or effect of loratadine by affecting hepatic enzyme CYP2D6 metabolism. If you feel Claritin isn't working for a full 24 hours, it isn't recommended to increase the dose over 10 mg without first consulting with your doctor. Monitor Closely (1)loratadine will increase the level or effect of amikacin by P-glycoprotein (MDR1) efflux transporter. . 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