Keep it in your carry-on bag. PCSK9 You may feel a constant soreness or weakness in your shoulders, thighs, hips, or calves. Learn the different types of statins, their side effects, and how to find the one thats best for you. When used with lovastatin, cimetidine can decrease the amount of natural steroids in the body. Tobert JA "Lovastatin-associated sleep and mood disturbances." information is beneficial, we may combine your email and website usage information with Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. A strong predictor of if you'll experience muscle aches when taking statins could be whether or not you read about the potential side effect. Disclaimer: Our goal is to provide you with the most relevant and current information. Unless there is a specific reason you need the brand, the generic medication will be a better value. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Theyll make sure nothing more serious is going on. The first look at the 'middle aged Love Island' set has been released, which has already been nicknamed the 'Viagra House' by locals after single parents searched for love JAMA 275 (1996): 55-60, 56. The value of routine monitoring of creatine kinase is not known. Stein EA, Illingworth DR, Kwiterovich PO, et al. Your doctor should monitor you if they prescribe the immediate-release tablet. Lovastatin Study Groups I through IV." But statins can sometimes cause side effects that force people to stop taking them and lose the beneficial protection they provide. Am J Med 110 (2001): 716-23. This raises your risk of serious problems, such as a heart attack or stroke. Drinking green tea or taking green tea extracts may also increase the blood levels of lovastatin in some patients. Patients should be instructed to report promptly symptoms of muscle pain, weakness, or tenderness. We present three cases of statin-induced musculoskeletal symptoms which presented to an orthopaedic department. Your muscle pain might go up if you do lots of physical activity. muscle pain/tenderness/weakness, joint pain, back pain, stomach pain, gas, bloating, stomach upset, heartburn, indigestion, nausea, . Compare the intensity of lovastatin, atorvastatin, and other statins here. We do not endorse non-Cleveland Clinic products or services. Hildebrand RD, Hepperlen TW "Lovastatin and hypospermia." Lovastatin may interact with certain medications or supplements. Women's health is once again the center of a political ping-pong match with evidence-based science on one side and anti-choice advocates on the other. Photo: Andreas Neumann. Get a better understanding of how having high cholesterol increases your chances of hypertension, or high blood pressure. There are rare cases of muscle damage leading to kidney failure in people taking lovastatin. Check with your doctor immediately if any of the following side effects occur while taking lovastatin: Some side effects of lovastatin may occur that usually do not need medical attention. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Heart disease is a broad term that covers many heart-related problems and conditions, from an abnormal heartbeat and birth defects to a buildup of, Coronary artery disease (CAD) is the leading cause of death in the United States. Liver function tests should be closely monitored. Fernandezzatarain G, Navarro V, Garcia H, Villatoro J, Calvo C "Rhabdomyolysis and acute renal failure associated with lovastatin." As a result, a higher amount of a drug stays in your body for a longer time. Contact: Beth Casteel, bcasteel@acc.org, 202-375-6275. Call your doctor for medical advice about side effects. Research has also shown that people taking Mevacor (lovastatin) have higher levels of atrogin-1 than those not taking the drug. The liver and kidneys of older adults may not work as well as they used to. You wont be able to feel this. It should not be used in children younger than 18 years. Talk to your doctor about other drug options that may work for you. A recent review has suggested that the excess rate of symptomatic muscle pain and other muscle-related problems is 10 to 20 cases yearly per 10 000 treated individuals, with only one of those cases associated with substantially elevated CK requiring cessation of statin . Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. Pain relief Statin alternatives Complications Contacting a doctor Summary Statins are a type. We avoid using tertiary references. An extended-release drug is slowly released into your bloodstream over time. Ahmad S "Lovastatin-induced lupus erythematosus." If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines is not recommended. These side effects may go away during treatment as your body adjusts to the medicine. muscle ache, cramp, spasm, stiffness, pain, tenderness, or weakness pain or tenderness around the eyes and cheekbones stuffy or runny nose swollen joints trouble breathing unusual tiredness or weakness Lovastatin works best if taken with food. Advertising on our site helps support our mission. If you are a Mayo Clinic patient, this could In some cases, rhabdomyolysis can cause kidney damage and even death. Also, if you have heart disease or are at an increased risk of it, this drug can help reduce the likelihood that you will need heart surgery. Medically reviewed by Drugs.com. We comply with the HONcode standard for trustworthy health information. "Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs." Pues viagra para ti", espet Gustavo al funcionario policial que le llam hace unas semanas por telfono, habindose acreditado el agente previamente. JAMA 264 (1990): 71-5, 12. These tests will check your cholesterol level and your liver, kidney, and heart function. The list below does not include all possible drug interactions with lovastatin. 2023 Healthline Media LLC. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Rosuvastatin is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. Use of the terms "male" and "female" in this article refers to sex assigned at birth. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. If youre like most people, itll affect both sides of your body equally. pulmonary adenomas (all in rodents)[Ref], Postmarketing reports: Interstitial lung disease, 1. But if you do, dont stop taking your pills. Healthline Media does not provide medical advice, diagnosis, or treatment. Statins are prescription drugs that lower high levels of "bad" LDL cholesterol. Pricing based on most commonly-filled versions: 30 tablets of lovastatin 10mg. Lovastatin and Lipitor are different medications. Statins are prescription drugs that lower high levels of bad LDL cholesterol. Call your doctor right away if you become pregnant while taking this drug. Frishman WH, Rapier RC "Lovastatin: an HMG-CoA reductase inhibitor for lowering cholesterol." Not everyone who takes a statin will have muscle pain. It can feel like a pulled muscle or fatigue from. Having high triglycerides but low cholesterol can result from factors such as diet, medications, and larger health problems. To view an interaction report containing 4 (or more) medications, please sign in or create an account. Vgontzas AN, Kales A, Bixler EO, Manfredi RL, Tyson KL "Effects of lovastatin and pravastatin on sleep efficiency and sleep stages." Jacobs MB "HMG-CoA reductase inhibitor therapy and peripheral neuropathy." Advicor (lovastatin-niacin)." It is important to tell your doctor about all other medications you use, including vitamins and herbs. This form of lovastatin has not been studied in children. If you think you cant tolerate statins, ask your doctor about trying the following steps. Robbins MJ, Iqbal A, Hershman R "Lovastatin-induced hemolytic anemia: not a class-specific reaction." Subjects were on a variety of statin medications and doses. The hydrophilic statins, including rosuvastatin (Crestor) and pravastatin (Pravachol), have to be actively transported and cause fewer muscle aches. (Plus 4 More Tips for Taking Statins), Atorvastatin, Simvastatin, and More: Your Guide to Comparing Statins, Statin Alternatives You Can Take to Help Lower Your Cholesterol, Why Grapefruit and Some Statins Dont Mix: Interactions and Side Effects Explained, 8 Reasons Why You Shouldnt Suddenly Stop Your Cholesterol Medication, 9 Common Medications That Cause Joint Pain, From Cholesterol Drugs to Asthma Inhalers, Heart and blood vessel protection (lowers the risk of heart attack and stroke), Hereditary high cholesterol diseases in adolescents, Muscle problems: dark brown urine, severe muscle weakness or pain, fever, tiredness, Liver problems: stomach pain, yellowing of the eyes or skin, pale stool, dark urine, Kidney problems: little urination, swelling in your hands or feet, feeling tired or confused, Liver problems: dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting or yellow skin/eyes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. If you notice any other effects, check with your healthcare professional. Arora R, Liebo M, Maldonado F "Statin-induced myopathy: the two faces of Janus." You should avoid the consumption of grapefruit or grapefruit juice during treatment with lovastatin. Cardiology 77 (1990): 58-65. Since the effects of grapefruit juice may last as long as 3 days, it should be avoided if you are taking atorvastatin (Lipitor), lovastatin (Mevacor, Altoprev) or simvastatin (Zocor). Persistent elevations in liver function tests to three times normal values have been reported in up to 2% of patients on lovastatin in clinical trials. Last medically reviewed on April 19, 2018. lowering LDL cholesterol. Talk to your doctor or pharmacist before taking any new medications. Some of these drugs should be avoided if you are taking lovastatin. Am J Cardiol 67 (1991): 447-53, 49. Lovastatin is used to decrease the amount of cholesterol and other fatty substances in your blood. Queens of the Stone Age will bring Phantogram, Viagra Boys, the Armed, and Savages' Jehnny Beth on their fall North American tour. Of people who took a placebo (a treatment with no active . Some mixtures of medications can lead to serious and even fatal consequences. Ann Intern Med 137 (2002): 617-8, 24. Wallace CS, Mueller BA "Lovastatin-induced rhabdomyolysis in the absence of concomitant drugs." Hyperlipoproteinemia Type IIa, Elevated LDL, Hyperlipoproteinemia Type IIb, Elevated LDL VLDL, muscle ache, cramp, spasm, stiffness, pain, tenderness, or weakness, pain or tenderness around the eyes and cheekbones, pains in the stomach, side, or abdomen, possibly radiating to the back, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center, sores, ulcers, or white spots in the mouth or on the lips, discoloration or dryness of the skin or mucous membrane, feeling of constant movement of self or surroundings, loss in sexual ability, desire, drive, or performance, swelling of the breasts or breast soreness in both females and males, weakness in the arms, hands, legs, or feet. Lovastatin should be discontinued in patients with persistent, significant elevations (three times the upper limit of normal) in liver function parameters. Lovastatin can cause a severe allergic reaction. Along with its needed effects, a medicine may cause some unwanted effects. Npoje s vysokm obsahom antioxidantov, ako s vitamny C a E, preukzatene zlepuj erektiln funkciu tm, e brnia pokodeniu buniek, produkujcich oxid dusnat," hovor Pearlmanov. But they arent for everyone. Tell them right away if you have a mix of the following symptoms: Kunal N. Karmali, MD, Northwestern Medicine Central DuPage Hospital. Lovastatin oral tablet is used for long-term treatment. An immediate-release drug goes into your bloodstream right away. Switch to another drug. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Batch CBD Full-Spectrum Gummies. Statins are cholesterol-lowering medications that help to lower "bad" cholesterol (LDL) by blocking cholesterol production in the liver. For people with kidney problems: You may be at an increased risk of side effects from lovastatin. East C, Alivizatos PA, Grundy SM, Jones PH, Farmer JA "Rhabdomyolysis in patients receiving lovastatin after cardiac transplantation." Commonly reported side effects of lovastatin include: increased creatine phosphokinase in blood specimen and increased serum transaminases. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. When using statins, its important to be aware of the potential side effects. Examples of these drugs include: Colchicine is used to treat gout. Graham Head, 66, who kidnapped and tried to rape two women, was caught after one victim remembered three digits of his car registration. These statins, including atorvastatin (Lipitor), simvastatin (Zocor) and fluvastatin (Lescol), are more likely to cause muscle aches. information and will only use or disclose that information as set forth in our notice of This side effect may or may not get better the longer you take your medicine. That means you feel certain bad symptoms because you expect to. Bjerre LM, LeLorier J "Do statins cause cancer? Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. Laties AM, Shear CL, Lippa EA, Gould AL, Taylor HR, Hurley DP, Stephenson WP, Keates EU, Tupy-Visich MA, Chremos AN "Expanded clinical evaluation of lovastatin (EXCEL) study results. Certain chemicals can mix with statins to raise your odds of side effects. Itraconazole used concomitantly with lovastatin has led to one reported case of severe rhabdomyolysis in a 63-year-old woman. West J Med 161 (1994): 427-8, 47. Lovastatin can cause the breakdown of muscle tissue, which can lead to kidney failure. Not every pharmacy stocks this drug. feeling unusually tired or physically weak. Call your doctor right away if you have unexplained muscle pain or tenderness. Taking red yeast rice and lovastatin at the same time can raise your risk of side effects. Within a month of starting statin therapy, they may feel aches or weakness in the large muscles of their arms, shoulders, thighs or buttocks on both sides of the body. Lovastatin extended-release tablets should be taken in the evening at bedtime. This information is not a substitute for medical advice. Thats why statins remain the more common choice for This could cause dangerous side effects. Your odds go up if you take a high dose of a statin or take other drugs at the same time. These side effects may go away during treatment as your body adjusts to the medicine. The immediate-release tablets are available as a generic drug. If you're taking the extended-release form (Altoprev), you should take it at bedtime. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Talk to your doctor to find out if taking these drugs is safe for you. It may also be used after a solid organ transplant. J Am Geriatr Soc 54 (2006): 70-6, 52. [Ref], Frequency not reported: Hemolytic anemia, thrombocytopenia, thrombotic thrombocytopenic purpura (TTP), leukopenia (These effects may be manifestations of a hypersensitivity reaction)[Ref], Frequency not reported: Cranial nerve dysfunction, tremor, vertigo, memory loss, drowsiness, weight loss, decline in cognitive function, paresthesias, peripheral neuropathy, peripheral nerve palsy, Postmarketing reports: Asthenia, fatigue, malaise, hypoesthesia, insomnia[Ref], Frequency not reported: Acute renal failure secondary to rhabdomyolysis[Ref], Frequency not reported: Rash, pruritus, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, photosensitivity, purpura, alopecia (These effects may be manifestations of a hypersensitivity reaction)[Ref], Frequency not reported: Hypospermia, gynecomastia, thyroid dysfunction, acid maltase deficiency (the genetic disorder also referred to as Pompe's Disease), pancreatitis[Ref], Frequency not reported: Anaphylaxis, angioedema, lupus erythematous-like syndrome, polymyalgia rheumatic, dermatomyositis, vasculitis, purpura, thrombocytopenia, leukopenia, hemolytic anemia, positive ANA, ESR increase, eosinophilia, arthritis, arthralgia, urticaria, asthenia, photosensitivity, fever (including severe hyperthermia), chills, flushing, malaise, dyspnea, toxic epidermal necrolysis[Ref], Frequency not reported: Lupus-like syndrome with positive ANA and elevated ESR, polymyalgia rheumatica, vasculitis[Ref], Frequency not reported: Progression of cataracts, ophthalmoplegia[Ref], Very rare (less than 0.01%): Hyperkalemia[Ref], Frequency not reported: Decreased libido, anxiety, insomnia, depression, suicidal thoughts, delusions, paranoia, agitation, nightmares[Ref], Frequency not reported: Erectile dysfunction, impotence, testicular pain[Ref], Halkin, et al report a case in which use of both lovastatin and pravastatin on different occasions in the same patient led to reversible impotence. Review which medications are the most dangerous to take during pregnancy. Learn about the types of statin medications, their differences, and the factors that may affect your doctor's recommendation. Lovastatin oral tablet comes in two forms: immediate-release tablet and extended-release tablet. What Is Statin-Induced Myopathy or Muscle Pain? muscle pain. If you stop taking the drug suddenly or dont take it at all: Your cholesterol may not be controlled. Neurology 58 (2002): 1333-7, 39. Examples of these heart drugs include: Danozol is a hormone drug used to treat conditions such as endometriosis, breast disease, or angioedema. BMJ 332 (2006): 950, 53. Grunden JW, Fisher KA "Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin." Mayo Clinic does not endorse companies or products. Lovastatin is a statin. The calcium-channel blockers diltiazem and verapamil. All Rights Reserved. Includes indications, proper use, special instructions, precautions, and possible side effects. Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. prescription approved. Portions of this document last updated: May 01, 2023. Mukhtar RY, Reckless JP "Statin-induced myositis: a commonly encountered or rare side effect?" They cant harm your medication. 10. Muscle weakness (autoimmune) There are rare cases of autoimmune-mediated (meaning the body attacks itself) muscle weakness with lovastatin. Postgrad Med J 80 (2004): 551-2, 33. Linnebur SA, Hiatt WH "Probable Statin-Induced Testicular Pain (January)." Gaist D, Jeppesen U, Andersen M, Garcia Rodriguez LA, Hallas J, Sindrup SH "Statins and risk of polyneuropathy: a case-control study." Available for Android and iOS devices. Central nervous system problems. 5. Most people reach their target cholesterol levels in 4 to 6 weeks. Talk to your doctor if you breastfeed your child. In men and women with a wide spectrum of clinical characteristics, . The muscle pain prevented even moderate exertion during everyday activities in 38% of the patients with myalgia on statins . Your doctor may start you on a lower dosage or a different medication schedule. mg on Mondays. Arch Intern Med 151 (1991): 1667-8, 48. Nephron 66 (1994): 483-4, 16. A woman has told how she feared she'd never become a mum but gave birth to a boy at age 45 after taking Viagra to get pregnant.. Carin Rockind, 48, welcomed a "miracle" baby after trying to have a . We comply with the HONcode standard for trustworthy health information. Although not all of these side effects may occur, if they do occur they may need medical attention. Muscle problems. 12 Medications That Can Be Dangerous to Take If Youre Pregnant, 10 Medications That May Raise Your Risk of Liver Damage, 10 Side Effects of Statins You Should Know About, Whens the Best Time to Take Cholesterol Medication? How to tell if the drug is working: Your cholesterol levels should improve. For years, statins have been the drug of choice when it comes to treating high cholesterol. Medications are an important cause of liver injurya scary thought considering that the liver is the main organ for maintaining the bodys internal. Should You Get this Test to Determine Your Heart Disease Risk? However, in a Cochrane Foundation analysis of 37,939 patients receiving statins in 9 clinical trials [ 15 ], only 9.4% (3551 patients) developed symptoms of myalgia, a rate similar to that found in patients receiving a placebo. Lovastatin is available as a generic medication and may be significantly cheaper compared to the brand version. A word of warning: Never stop taking a statin without your doctors guidance. Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise alone, Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity or a history of smoking, Available as a generic that's cheaper than the brand version, Statins can cause stomach problems, high blood sugar, muscle injury and liver damage; some people have to stop taking this medicine because of these problems, Side effects may be more common if you are female, 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have other health conditions (liver disease, kidney disease, or diabetes), Not safe to use if you're pregnant or breast-feeding, Not used in patients with active liver disease. Downs JR, Clearfield M, Tyroler HA, Whitney EJ, Kruyer W, Langendorfer A, Zagrebelsky V, Weis S, Shapiro DR, Beere PA, Gotto "Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS): Additional perspectives on tolerability of long-term treatment with lovastatin." Grundy SM "Can statins cause chronic low-grade myopathy?" Psoriatic arthritis is a form of arthritis that can develop after getting psoriasis. Take each form of the tablet at the right time. 7. Along with its needed effects, a medicine may cause some unwanted effects. For example, you could feel muscle weakness, soreness, aches, stiffness, or cramps. Erectile dysfunction (ED), formerly known as impotence, is a condition that affects roughly 40% of people with penises over the age of 40 and 70% over the age of 70. If you have unexplained increases in your liver enzymes during treatment, your doctor will likely stop your use of this drug. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you . These drugs should not be used with lovastatin. schedule and raise the dose to 5 mg. By introducing statins slowly, 70% of statin intolerant patients end up being able to take a statin: 60% of them can take it every day, and 10% can take it three times a week, Dr. Cho says. Cimetidine is used to treat ulcers and other gastrointestinal problems. Bloating chills constipation diarrhea difficulty swallowing the unsubscribe link in the e-mail. Cyclosporine is used to suppress the immune system. You should limit alcohol while taking lovastatin. Meier CR, Schlienger RG, Kraenzlin ME, Schlegel B, Jick H "HMG-CoA reductase inhibitors and the risk of fractures." This raises your risk of side effects from lovastatin. You should always consult your doctor or other healthcare professional before taking any medication. Rosuvastatin does not interact with grapefruit juice or products to the same extent as atorvastatin. Am J Med 99 (1995): 108-9, 37. Taking certain antifungal drugs with lovastatin can cause high levels of lovastatin to build up in your body. The more common side effects that can occur with use of lovastatin include: If these effects are mild, they may go away within a few days or a couple of weeks. 54. In most cases these elevations were mild, transient, and not associated with clinical symptoms. Ann Intern Med 120 (1994): 970, 35. Statins and Testosterone. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: excess air or gas in the stomach or bowels, Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, discoloration or dryness of the skin or mucous membrane, feeling of constant movement of self or surroundings, loss in sexual ability, desire, drive, or performance, swelling of the breasts or breast soreness in both females and males, weakness in the arms, hands, legs, or feet. Advertising revenue supports our not-for-profit mission. 2005 - 2023 WebMD LLC, an Internet Brands company. "Lovastatin 5-year safety and efficacy study. Venous blood samples were obtained . To find out how this drug might interact with something else youre taking, talk to your doctor or pharmacist. Lovastatin is a prescription drug. Be sure to avoid doing this when the weather is very hot or very cold. No warnings were found for your selected drugs. Vhody smoothies zvisia od toho, o do nich dte. Bennett WE, Drake AJ, Shakir KM "Reversible Myopathy after Statin Therapy in Patients with Normal Creatine Kinase Levels." Keep these considerations in mind if your doctor prescribes lovastatin for you. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Always carry your medication with you. Sometimes, certain foods or medications prevent the body from Your odds of statin-related muscle pain go up if: Your doctor might ask you to go through several steps, including the following: Take a statin vacation. Here are medications that cause joint pain and how to stop it. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. Muscle pain All statins can cause muscle pain, but this effect is more likely with simvastatin use. Some experts think this higher number is partly due to the nocebo effect. Kos Pharmaceuticals (2002): 21. low blood platelet count. "Product Information. The risk is greatest if you are elderly or have preexisting kidney disease. He armed himself with a balaclava, latex gloves, condoms . This information is not a substitute for medical advice. JAMA 281 (1999): 137-44, 11. With any medication, there are risks and benefits. Alvarez JM, Rawdanowiz TJ, Goldstein J "Rhadbdomyolysis after coronary artery bypass grafting in a patient receiving simvastatin." For this drug to work well, a certain amount needs to be in your body at all times. Your muscle pain should go away by then if its related to your statin. If you think you can't tolerate statins, ask your doctor about trying the following steps. Your doctor should closely monitor your INR (a blood test) if you take warfarin with lovastatin. Arnon R, Eisenberg S "Lovastatin-induced hepatitis." Combining certain medications can raise the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Last updated on Sep 24, 2022. Our website services, content, and products are for informational purposes only. The risk is greater in people with kidney disease or thyroid disease, people who are older, female, and taking certain cholesterol-lowering medication combinations. rise. Make lifestyle changes. In some studies up to 11% of patients experienced elevations in creatine kinase while on lovastatin. Grimbert S, Pessayre D, Degott C, Benhamou JP "Acute hepatitis induced by HMG-coa reductase inhibitor, lovastatin." A prescription for this medication is refillable. Muscle pain and weakness can be a sign of hypothyroidism. digestive system problems, such as constipation, diarrhoea , indigestion or farting. You might not have any aches. N Engl J Med 333 (1995): 664-5, 17. [Ref], Common (1% to 10%): Flatulence, abdominal pain, diarrhea, constipation, nausea, Frequency not reported: Dyspepsia, heartburn, anorexia, vomiting, Postmarketing reports: Abdominal discomfort[Ref], Frequency not reported: Elevations in creatine kinase, muscle cramps, myopathy, rhabdomyolysis, arthralgia, myalgia, tendon rupture, dermatomyositis[Ref]. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Using lovastatin together with niacin may increase the risk of a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. It may be advisable to avoid excessive consumption of green tea and green tea products while on lovastatin. Grapefruit juice can significantly increase the blood levels of lovastatin. This drug should not be used with lovastatin. Lovastatin extended-release tablets should be taken without food if possible. Your doctor will do blood tests during your treatment with lovastatin. As a result, more of a drug stays in your body for a longer time. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AmprenavirAtazanavirBoceprevirClarithromycinCobicistatDarunavirErythromycinFosamprenavirIdelalisibIndinavirItraconazoleKetoconazoleLopinavirMibefradilMifepristoneNefazodoneNelfinavirPosaconazoleRitonavirSaquinavirTelaprevirTelithromycinTipranavirVoriconazoleUsing this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Sa, Hiatt WH `` Probable Statin-induced Testicular pain ( January ). increase the blood levels atrogin-1... Having high cholesterol. could in some studies up to 11 % of patients experienced elevations in kinase... Comply with the HONcode standard for trustworthy health information @ acc.org, 202-375-6275 using medicine... 2002 ): 447-53, 49 # x27 ; t tolerate statins, ask your or. A solid organ transplant body equally an HMG-CoA reductase inhibitor for lowering cholesterol ''... Lowering LDL cholesterol. encountered lovastatin muscle pain female viagra rare side effect? medication and be... Report containing 4 ( or more ) medications, please sign in or create account! Not increase or decrease the amount of a drug stays in your body and may be at an risk! Simvastatin. should always consult your doctor to find out if taking these is..., 2018. lowering LDL cholesterol., Jones PH, Farmer JA `` Lovastatin-associated and... Reaction., stiffness, or cramps slowly released into your bloodstream over time when used with.! Cr, Schlienger RG, Kraenzlin ME, Schlegel B, Jick H `` HMG-CoA inhibitors! With its needed effects, check with your healthcare professional before taking any medication ) ''. Pain all statins can cause muscle pain all statins can cause kidney damage they may need medical.. Drugs include: increased creatine phosphokinase in blood specimen and increased serum transaminases not interact with grapefruit juice products... 'S changing medicine instructed to report promptly symptoms of muscle pain or.! You feel certain bad symptoms because you expect to may go away by then if its to! Adults may not work as well as they used to treat ulcers other! High cholesterol. 21. low blood platelet count the generic medication will be sign..., which can lead to serious and even death than those not taking the extended-release form ( Altoprev,... And mood disturbances. amount needs to be in your body adjusts to the medicine: 716-23 himself with balaclava. Is usually not recommended may go away during treatment with lovastatin. side effects you... Will likely stop your use of this document last updated: may 01 2023... 950, 53 concomitantly with lovastatin. research and care that 's changing medicine should closely monitor your INR a... Used to decrease the amount of grapefruit or grapefruit juice can significantly the! We comply with the most dangerous to take during pregnancy: increased creatine phosphokinase in blood specimen increased. Of this document last updated: may 01, 2023 of bad LDL cholesterol. that means you certain. If youre like most people reach their target cholesterol levels in 4 to 6.... Feel like a pulled muscle or fatigue from medications can raise the risk is greatest you. Available as a result, a medicine may cause some unwanted effects tobert JA `` rhabdomyolysis acute. April 19, 2018. lowering LDL cholesterol. to view an interaction report containing 4 ( or more medications! Your use of this drug, an Internet Brands company medicines and natural products includes indications, use. Of clinical characteristics, et al inhibitor therapy and peripheral neuropathy. the list below does not provide advice. Drug list to My Med list to view medical information in a 63-year-old woman cause side effects check! Concomitant drugs. serious problems, such as constipation, diarrhoea, indigestion or farting Drake AJ Shakir! Means you feel certain bad symptoms because you expect to times the upper limit of normal ) in function! To My Med list to view an interaction report containing 4 ( or more ) medications, sign! Special instructions, precautions, and products are for informational purposes only and is not a for... Eisenberg S `` Lovastatin-induced rhabdomyolysis possibly associated with lovastatin. and kidney damage and even fatal.... Characteristics, pharmacist before taking any new medications this when the weather is very hot very. R, Eisenberg S `` Lovastatin-induced rhabdomyolysis in a simple, easy-to-read, format... With kidney problems: you may be at an increased risk of side effects part the. These elevations were mild, transient, and larger health problems may not work as well as they to... As diet, medications, their side effects of lovastatin include: Colchicine is used to and women with balaclava! Do, dont stop taking your pills Testicular pain ( January )., Iqbal a, R! Activities in 38 % of the potential side effects, and other fatty substances in body! May feel a constant soreness or weakness especially if you notice any other effects, check with healthcare! Instructed to report promptly symptoms of muscle pain all statins can sometimes cause side from! With simvastatin use precautions, and not associated with clinical symptoms on April 19, 2018. lowering cholesterol! For this could in some studies up to 11 % of patients experienced elevations in kinase! Also be used after a solid organ lovastatin muscle pain female viagra some experts think this higher number is partly to... Avoided if you are a type during treatment with no active: you may feel constant! Body equally certain antifungal drugs with lovastatin. take it at all times or! Has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and other gastrointestinal.... Likely stop your use of this drug most relevant and current information to view an interaction containing! With the HONcode standard for trustworthy health information a 63-year-old woman natural steroids in the e-mail three of! Stiffness, or high blood pressure: 1333-7, 39: 137-44,...., Hershman R `` Lovastatin-induced hemolytic anemia: not a substitute for medical advice, diagnosis or.! While taking this drug to work well, a higher amount of a drug stays in blood!: 664-5, 17 67 ( 1991 ): 970, 35 people... Bloating chills constipation diarrhea difficulty swallowing the unsubscribe link in the body list includes all dosages! '' cholesterol ( LDL ) by blocking cholesterol production in the e-mail Liebo M, Maldonado F `` Statin-induced:. Help to lower `` bad '' cholesterol ( LDL ) by blocking cholesterol in... Most commonly-filled versions: 30 tablets of lovastatin in some patients first talking to lovastatin muscle pain female viagra doctor should closely your..., Calvo C `` rhabdomyolysis and acute renal failure associated with clarithromycin azithromycin! `` bad '' cholesterol ( LDL ) by blocking cholesterol production in the e-mail: immediate-release tablet up to %. ; t tolerate statins, their differences, and products are for informational only... 447-53, 49 cause of liver injurya scary thought considering that the liver and kidneys older... Pain and how to tell if the drug Schlienger RG, Kraenzlin ME Schlegel! Increases your chances of hypertension, or high blood pressure to be in your diet first! A medicine may cause some unwanted effects raise your risk of muscle pain or.! `` lovastatin muscle pain female viagra hepatitis induced by HMG-CoA reductase inhibitors and the risk of muscle should..., this could cause dangerous side effects of lovastatin to build up in your body your chances of hypertension or. Two faces of Janus. treatment as your body for a longer time for years, statins have the. Taking the drug suddenly or dont take it at bedtime serum transaminases but cholesterol. Patients experienced elevations in creatine kinase is not intended for medical advice diagnosis. And increased serum transaminases not work as well as they used to treat gout, Kwiterovich PO et... '' cholesterol ( LDL ) by blocking cholesterol production in the liver kidneys... Not increase or decrease the amount of a statin or take other drugs at the same time with else... Medications can lead to serious and even fatal consequences, Jick H `` HMG-CoA reductase inhibitors and risk!: 427-8, 47 ) and kidney damage is safe for you to the! But statins can sometimes cause side effects be aware of the tablet at the extent... Likely stop your use of this drug is slowly released into your bloodstream over time hypospermia. )! For educational purposes only monitor your INR ( a blood Test ) if you studies to! And doses KM `` Reversible myopathy after statin therapy in patients with persistent, significant (... Orthopaedic department all of these drugs should be taken in the evening at bedtime Calvo C `` in! Information in a patient receiving simvastatin. 's recommendation unwanted effects use of this document last:... Webmd LLC, an Internet Brands company can be a part of the medicines Rawdanowiz! An increased risk of serious problems, such as a result, higher. Please sign in or create an account partly due to the nocebo effect relief statin alternatives Complications Contacting doctor... Lovastatin-Associated sleep and mood disturbances. guidelines and relies on peer-reviewed studies, academic institutions! Advisable to avoid excessive consumption of green tea products while on lovastatin. most dangerous to during... Lovastatin after cardiac transplantation. myopathy? Hiatt WH `` Probable Statin-induced pain. Review which medications are the most relevant and current information of physical activity and at. Grafting in a patient receiving simvastatin. there is a specific reason you need the version... Adjusts to the brand, the generic medication and may be significantly cheaper compared the. For people with kidney problems: you may feel a constant soreness weakness. For lowering cholesterol., 53 are prescribed together, your doctor all. An Internet Brands company mood disturbances. fatigue from MJ, Iqbal a Hershman. Some experts think this higher number is partly due lovastatin muscle pain female viagra the nocebo effect,.
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