Olanzapine - how well does Zyprexa work for sleep? Opioids should not be taken too soon before and after treatment with olanzapine/samidorphan. For females, this increase in prolactin may result in unwanted breast milk, missed/stopped periods, or difficulty becoming pregnant. Do not stop taking olanzapine or change your dose without talking to with your health care provider first. It may also be used alone or with other medicines (eg, lithium or valproate) to treat mania or mixed episodes that is part of bipolar disorder (manic-depressive illness). If you are planning on becoming pregnant, notify your health care provider to best manage your medications. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Second generation antipsychotics (SGAs) increase the risk of diabetes, weight gain, high cholesterol, and high triglycerides. tell your doctor if you use tobacco products. https://www.drugs.com/sfx/zyprexa-side-effects.html. If you are taking or using any other medicines. This is so your progress can be checked. It is taken once daily. Do not take extra medicine to make up for a missed dose. you should know that olanzapine may make it harder for your body to cool down when it gets very hot. Olanzapine may cause problems in newborns following delivery if it is taken during the last months of pregnancy. WebMD does not provide medical advice, diagnosis or treatment. Some medicines can affect how olanzapine works. Compare bipolar 1 vs. 2, how it is treated, and how to support a loved one with bipolar disorder. Latuda doesn't work for everyone. Drowsiness, dizziness, lightheadedness, weight gain, or pain/redness/swelling at the injection site may occur. Your doctor may order certain lab tests to check your body's response to olanzapine. Your treatment will require careful monitoring to make sure that you get the best possible benefit from olanzapine. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Olanzapine 15 Mg-Samidorphan 10 Mg Tablet, Enter your medication into the WebMD interaction checker. Still looking for answers? If you have diabetes you may need to check your blood glucose more frequently, as olanzapine may affect the levels of sugar in your blood. . The major toxicity of olanzapine was grade 1 and 2 sedation or drowsiness (25 patients). Speak with a pharmacist if your weight becomes troublesome, Speak with your doctor about this. If an overdose occurs, call your doctor or 911. To minimize this risk, antipsychotic medications should be used in the smallest effective dose when the benefits outweigh the risks. Close the bottle tightly. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. It belongs to a group of medications called antipsychotics. Provigil or Nuvigil would help with getting going in the morning. This information is for educational and informational purposes only and is not medical advice. This information is being provided as a community outreach effort of the American Association of Psychiatric Pharmacists. Ways to manage this side effect include: Speak to your provider if this side effect continues to be a problem. If you develop symptoms of TD, such as grimacing, sucking, and smacking of lips, or other movements that you cannot control, contact your health care provider immediately. Keep all medications away from children and pets. All antipsychotics can cause sedation, dizziness, or orthostatic hypotension (a drop in blood pressure when standing up from sitting or lying down). Systematic reviews of second-generation antipsychotics concluded that olanzapine seems to be a first-line agent during breastfeeding. Get the full list here. Tell your doctor if you have any kind of heart or circulation problems, including low blood pressure, heart failure, heart rhythm problems, or a history of a heart attack or stroke. Olanzapine is a generic medication also sold under the brand name Zyprexa. The strength and quantity needed will affect how much Olanzapine costs. dizziness, feeling unsteady, or having trouble keeping your balance, difficulty falling asleep or staying asleep, swelling of the arms, hands, feet, ankles, or lower legs, unusual movements of your face or body that you cannot control, sore throat, fever, chills, and other signs of infection, rash that may occur with fever, swollen glands, or swelling of the face, coma (loss of consciousness for a period of time). You should consult with your provider before becoming pregnant or fathering a child while on this medication. All Rights Reserved. Smoking may affect the amount of olanzapine in your body. Keep all appointments. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Your doctor will do lab tests at regular visits to check on the effects of this medicine. high fever excessive sweating rigid muscles confusion changes in breathing, heartbeat, or blood pressure DRESS warning: Olanzapine can cause a condition called drug reaction with eosinophilia and. Be sure to mention any of the following: antidepressants; antihistamines; carbamazepine (Tegretol); dopamine agonists such as bromocriptine (Parlodel), cabergoline (Dostinex), levodopa (Dopar, Larodopa), pergolide (Permax), and ropinirole (Requip); fluoroquinolone antibiotics including ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the United States), levofloxacin (Levaquin), norfloxacin (Noroxin), ofloxacin (Floxin), others; fluvoxamine (Luvox); ipratropium (Atrovent); medications for anxiety, high blood pressure, irritable bowel disease, mental illness, motion sickness, Parkinson's disease, seizures, ulcers, or urinary problems; omeprazole (Prilosec); rifampin (Rifadin); sedatives; sleeping pills; ticlopidine (Ticlid); and tranquilizers. Instead, use dry hands to peel back the foil packaging. the majority of patients were women and age 55 years. Do not try to push the orally disintegrating tablet through the foil. Dizziness and lightheadedness can increase the risk of falling. More serious side effects can also occur. Thanks masso. http://www.upandaway.org. You may also contact the poison control center at 1-800-222-1222. Olanzapine is a medication used to treat schizophrenia, bipolar disorder, and depression. Olanzapine targets receptors in the brain that have been linked to nausea and vomiting. Do not store in the bathroom. Keep your regular appointments with your doctor. Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. tell your doctor and pharmacist if you are allergic to olanzapine or any other medications. If you have any questions about this medicine ask your pharmacist. Your doctor may order an EKG to monitor for irregular heartbeat. Abilify, Haloperidol, Zyprexa, Seroquel, and Invega are some risperidone alternatives. You may also feel lightheaded when getting up suddenly from a lying or sitting position, so stand up slowly. MetabolicVery common (10% or more): Increased weight (up to 30%), increased appetite (up to 24%). The risk of opioid overdose is also higher if you take opioids after recently stopping olanzapine/samidorphan. Read the Medication Guide provided by your pharmacist before you start taking olanzapine/samidorphan and each time you get a refill. Does Olanzapine 15 Mg-Samidorphan 10 Mg Tablet interact with other drugs you are taking? The dose and how often you take olanzapine will depend on the cancer treatment you are getting. Alternatively, if you prefer, you can take the orodispersible tablet stirred into a small glassful of any of the following drinks: water, orange or apple juice, milk or coffee. Olanzapine is an antipsychotic that is used to treat schizophrenia and bipolar disorder. For additional information, including an up-to-date list of pharmacies, or assistance with any problems related to this prescription drug discount plan, please contact customer service toll free at 844-234-3057, 24 hours a day, 7 days a week (except major holidays). Follow your doctor's instructions carefully. If you miss a dose of olanzapine long-acting injection, see your healthcare provider to receive your dose as soon as possible. Olanzapine is not approved by the Food and Drug Administration (FDA) for the treatment of behavior disorders in older adults with dementia. If you notice other effects not listed above, contact your doctor or pharmacist. It is unknown if samidorphan passes into breast milk. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. Olanzapine belongs to a group of medications called atypical or second-generation antipsychotics. Some people may develop muscle related side effects while taking olanzapine. Olanzapine. Upgrade to Patient Pro Medical Professional? Do not share this medication with others. *Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. If you are taking the orally disintegrating tablet version, peel back the foil on the blister pack (do not push tablet through the foil) and remove it from the blister pack with dry hands. This product is not approved for the treatment of dementia-related behavior problems. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. If these effects make it hard to carry out daily life, talk with your provider. You should consult with your healthcare team before breastfeeding while receiving this medication. NAMI is a 501(c)(3) nonprofit (EIN 43-1201653). This risk is higher for people with conditions or other medications that could worsen these effects. 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