Stay lying down for a few minutes while the suppository melts. If you have questions about side effects, call your doctor. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care providers examination and assessment of a patients specific and unique circumstances. From diagnosis to treatment, our experts provide the care and support you need, when you need it. Use sunscreen and wear protective clothing when outdoors. Background. Vomiting. Compro (prochlorperazine) is a member of the phenothiazine antiemetics drug class and is commonly used for Anxiety, Nausea/Vomiting, and Psychosis. Also tell them if you smoke, drink alcohol, or use illegal drugs. light-colored stools, throwing up, or yellow skin or eyes. Be careful going up and down If you must be in the sun, wear cool clothing. You may also report side effects at https://www.fda.gov/medwatch. Detailed drug Information for Pms-Prochlorperazine. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. It is a less preferred medication for anxiety. Contraindications Tell the doctor about the allergy and what signs your child had. Available for Android and iOS devices. studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of prochlorperazine suppository in children 2 years of age and older or weighing 9 kilograms (kg) (20 pounds (lbs)) and over. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Prochlorperazine (Compro) is a rectal suppository used to treat severe nausea and vomiting. Overdose can cause dry mouth, constipation, bloating or stomach cramps, extreme drowsiness or feeling restless and agitated, changes in heart rate, fever, and fainting. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of prochlorperazine suppository in the elderly. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Drink plenty of water. Prochlorperazine is not approved for use in older adults with dementia-related psychosis. If you have trouble controlling your body temperature, call your care team right away. This includes prescription and over-the-counter medicines, vitamins, and herbal products. US residents can call their local poison control center at 1-800-222-1222. Prochlorperazine tablets are also used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). advice about side effects. They may be at greater risk when they are sick (such as having viral infection, dehydration). Signs of liver problems like dark urine, tiredness, decreased appetite, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. It may not cover all possible information. Manufacturer. Signs of an allergic reaction, like rash; Trouble controlling body movements, twitching, change in balance, trouble swallowing or speaking. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. If you notice other effects not listed above, contact your doctor or pharmacist. Sildenafil (Viagra, Revatio) is a moderately priced drug used to treat erection problems in men.It is also used to treat pulmonary arterial hypertension, a serious heart and lung condition.This drug is more popular than comparable drugs. Do not overheat. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Tell all of your health care providers that you take this medicine (prochlorperazine suppositories). nausea and vomiting caused by cancer drugs, prevent nausea and vomiting from cancer chemotherapy, FDA Labeling for prochlorperazine suppository, rectal on RxList. studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of prochlorperazine suppository in children 2 years of age and older or weighing 9 . Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). This is a decision you and your doctor will make. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. You may report side effects to the FDA at 1-800-FDA-1088. If suppository is soft, chill in a refrigerator or run cold water over it. Do not drive or operate machinery until you know how this medication affects you. If you notice any other effects, check with your healthcare professional. A single copy of these materials may be reprinted for noncommercial personal use only. Like other phenothiazines, it exerts an antiemetic effect through a depressant action on the chemoreceptor trigger zone. Store at room temperature away from moisture and heat. Stay out of the sun when possible. Child 2-4 years. Get medical help right away if you have any very serious side effects, including: seizures. Pay less for prochlorperazine with GoodRx Gold. The risk may be higher in patients who already have diabetes. Older adults may be more sensitive to the side effects of this drug, especially low blood pressure, constipation, urinary problems, and nerve/muscle problems. Includes common brand names, drug descriptions, warnings, side effects and dosing information. How to use. PROCHLORPERAZINE (proe klor PER a zeen) treats nausea and vomiting. Use in . Make sure you know how you react to this medicine before you drive, use machines, or do other jobs that require you to be alert, well-coordinated, or able to think or see well. The phase IV clinical study analyzes what interactions people who take Prochlorperazine maleate and Viagra have. Dopamine-blocking properties less than prochlorperazine; more antihistaminic qualities IV: $2.29 (generic) or $2.97 (brand) per 25-mg vial Suppository: $3.37 to $4.46 per dose Prochlorperazine is administered rectally. Be careful in hot weather or while being active. However, many people have no side effects or only have minor side effects. Do not take rectal suppositories by mouth or use it in the vagina. Have your childs blood work checked often. Not sweating during activities or in warm temperatures. escitalopram, duloxetine, alprazolam, hydroxyzine, Lexapro, ondansetron, lorazepam, Xanax, Cymbalta, Zofran. Store at room temperature in a dry place. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Some drugs may have another patient information leaflet. Talk to your pharmacist for more details. Version: 6.01. escitalopram, duloxetine, alprazolam, hydroxyzine, Lexapro, ondansetron, lorazepam, Xanax, Cymbalta, Zofran. Apply gentle pressure to insert the suppository completely into the rectum, pointed end first. You will need to talk about the benefits and risks To use, take off foil wrapper and wet suppository with cold water. While this medication may be prescribed for children as young as 2 years for selected conditions, precautions do apply. Store at room temperature in a dry place. It is associated with a wide range of side effects, including drowsiness, and is not suitable for. The use of the eHealthMe site and its content is at your own risk. Chapter provides you with the most comprehensive Medicare guidance in America at no cost to you. Prochlorperazine Suppositories, USP 25 mg are indicated in the control of severe nausea and vomiting in adults. CLOSE. Wet the tip of the suppository with cold tap water to make it easier to use. Monday through Friday, 8 a.m. to 6 p.m. (Eastern time), Monday through Friday, 9 a.m. to 5 p.m. (Eastern time), Monday to Friday, 8 a.m. to 6 p.m. (Eastern time). If your child needs to stop this drug, you will want to slowly stop it as told by the doctor. Prochlorperazine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. Use your finger to push the suppository well up into the rectum. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Store at room temperature protected from light. Call your childs doctor for medical advice about side effects. Prochlorperazine may cause serious side effects. Give this drug as ordered by your childs doctor. CONTRAINDICATIONS. Do not start, stop, or change the dose of If you're a patient at MSK and you need to reach a provider after. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. If you have any questions about this drug, please talk with your childs doctor, nurse, pharmacist, or other health care provider. Terms of Use. $ 8.68. This medication may increase blood sugar. There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. Copyright: Merative US L.P. 1973, 2023. This information from Lexicomp explains what you need to know about this medication, including what its used for, how to take it, its side effects, and when to call your healthcare provider. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Keep out of the sun. Apply gentle pressure to insert the suppository completely into the rectum, pointed end . Avoid driving and doing other tasks or actions that call for you to be. It is created by eHealthMe based on reports of 33 people who take Prochlorperazine maleate and Viagra from the FDA, and is updated regularly. Alcohol may interact with this drug. You may store the suppositories in the refrigerator, but do not freeze them. Gently insert the suppository into your rectum about 1 inch, pointed tip first. stairs. Following intramuscular administration of Prochlorperazine edisylate, the drug has an onset of action . Ready to start planning your care? If your cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. Things to remember when you fill your prescription. It can lower the response of your body to cold temperatures. Do not give this drug to a child younger than 2 years of age. Talk with the doctor. It works by blocking substances in your body that may cause nausea and vomiting. If you are 65 or older, use this medicine (prochlorperazine suppositories) with care. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. 37 prochlorperazine as the edisylate, 5 mg sodium biphosphate, 12 mg sodium tartrate, 0.9 mg 38 sodium saccharin and 0.75% benzyl alcohol as preservative. Do not double doses. Get medical help right away if you have any of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, signs of kidney problems (such as change in the amount of urine). Canada residents can call a provincial poison control center. Prochlorperazine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It is for use only in your rectum. You may report side effects to Health Canada at 1-866-234-2345. If suppository is soft, chill in a refrigerator or run cold water over it. To lower the chance of feeling dizzy or passing out, have your child rise slowly if your child has been sitting or lying down. This medication may be prescribed for other uses. In Canada - Call your doctor for medical advice about side effects. This is not a list of all drugs or health problems that interact with this drug. If you need to store this drug at home, talk with your childs doctor, nurse, or pharmacist about how to store it. Drug information provided by: Merative, Micromedex US Brand Name. Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). Most Popular All Pharmacies; RITE AID PHARMACY: $49.57 With Free Coupon. Caution should be exercised when prochlorperazine is administered to a nursing woman. You will need to talk about the benefits and risks to your child and the baby. it damages the myelin sheath): 3 people, 9.09%, Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 9.09%, Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 6.06%. You should not use prochlorperazine if you have recently used alcohol, sedatives, tranquilizers, or opioid medication. Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation . Avoid using the bathroom for at least an hour. Do not give to your child more often than told by the doctor. Call your childs doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away: These are not all of the side effects that may occur. Call your doctor or get medical Also, use extra care not to become too cold while you are receiving risperidone injection. Prochlorperazine edisylate is administered by deep IM injection, direct IV injection, or IV infusion. Common side effects of prochlorperazine may include: breast swelling or discharge, a missed menstrual period; This is not a complete list of side effects and others may occur. Have your child be careful going up and down stairs. These are things like riding a bike, playing sports, or using items such as scissors, lawnmowers, electric scooters, toy cars, or motorized vehicles. Advertising on our site helps support our mission. Set Dosage 12 Suppository / 12 Box. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. ChildrenUse and dose must be determined by your doctor. It may be given to you for other reasons. Throw away unused or expired drugs. It is very important that your doctor should check the progress of you and your child at regular visits to make sure this medicine is working properly. Prochlorperazine 25 mg suppositories are indicated in the control of severe nausea and vomiting in adults. Follow your doctor's orders or the directions on the label. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. 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