Measure it with a marked measuring spoon, oral syringe, or medicine cup. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Make sure to discuss your current medication list with your pharmacist and healthcare provider. Spironolactone is an older, affordable medication thats still often used today. Antidepressant withdrawal: Is there such a thing? If we combine this information with your protected Follow your doctor's orders or the directions on the label. Libido usually improves on lower doses of the medication or when its stopped. Its still used today to treat several conditions, such as heart failure, high blood pressure, and fluid buildup. There is 1 alcohol/food interaction with spironolactone. Eplerenone and spironolactone have varying degrees of binding to the androgen and progesterone receptors with eplerenone being the least likely to inhibit it. Spironolactone comes as an oral tablet and an oral suspension. GoodRx can help you save over 86% off the average retail price of the generic version. Hypothyroidism: Should I take iodine supplements? Along with its needed effects, a medicine may cause some unwanted effects. Phosphodiesterase-5 inhibitors may markedly increase the hypotensive effects of nitrates. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Definition and facts of adrenal insufficiency & Addison's disease. Portions of this document last updated: May 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/spironolactone-oral-route/side-effects/DRG-20071534. To be cautious, limit the acetaminophen dosage to 2 g per day for no more than seven days and complete more frequent INR testing.18, Direct oral anticoagulant interactions inhibit factor Xa (rivaroxaban [Xarelto], apixaban [Eliquis], edoxaban [Savaysa]) or directly inhibit thrombin (dabigatran [Pradaxa]).23 Direct oral anticoagulant interactions are attractive alternatives to warfarin for some indications because of their ease of administration, no requirement for INR monitoring, no interaction between vitamin K or food, and comparable effectiveness and safety profiles.24 However, clinically significant interactions occur with drugs that share common metabolic pathways with direct oral anticoagulant interactions.23 Drugs that inhibit both CYP3A4 and P-gp can pose the greatest interaction and increase bleeding risk with direct oral anticoagulant interactions. Theres not enough research to support using spironolactone to treat or prevent COVID-19. There are 371 drugs known to interact with Strategies for reducing the risk of drug-drug interactions include minimizing the number of drugs prescribed, re-evaluating therapy on a regular basis, considering nonpharmacologic options, monitoring for signs and symptoms of toxicity or effectiveness, adjusting dosages of medications when indicated, and adjusting administration times. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Patients in the study may take other drugs besides Spironolactone and Cialis. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Common off-label uses for spironolactone include: Hirsutism (male-pattern hair growth in females), Part of estrogen-based gender-affirming hormone therapy (GAHT), Part of a medication regimen some people take after having a heart attack. Strategies for managing sexual dysfunction induced by antidepressant medication. Spironolactone can cause loss of sodium through the urine. How it works Spironolactone is a medicine used in a variety of heart-related and fluid-retaining conditions. South_agency/E+ via Getty Images View interaction reports for spironolactone and the medicines listed below. AdultsAt first, 100 milligrams (mg) per day, taken in either single or divided doses. But it can be frustrating and uncomfortable. Beta blockers should be tapered and discontinued several days before clonidine withdrawal to reduce the risk of rebound hypertension. It's also used to. Please check with a physician if you have health questions or concerns. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023 . Spironolactone has active ingredients of spironolactone. Other times, you may need to stop the medication to relieve this side effect. MARY CARPENTER, PharmD, HOLLY BERRY, PharmD, AND ALLEN L. PELLETIER, MD, Medical College of Georgia at Augusta University, Augusta, Georgia, Related letter: Potential Drug Interactions in Patients Taking Oral Contraceptive Pills. All rights reserved. Irregular menstrual cycles are common when taking spironolactone for acne. This medicine may cause swelling of the breasts (gynecomastia) and breast pain in some patients. Spironolactone is also used to lessen the need for hospitalization for heart failure. clear or bloody discharge from the nipple, decrease in urine output or decrease in urine-concentrating ability, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, persistent crusting or scaling of the nipple, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, sore on the skin of the breast that does not heal, sores, ulcers, or white spots on the lips or in the mouth, swelling of the face, fingers, feet, ankles, or lower legs, swollen, painful, or tender lymph glands in the neck, armpit, or groin, unsteadiness, trembling, or other problems with muscle control or coordination, vomiting of blood or material that looks like coffee grounds, numbness or tingling in the hands, feet, or lips, rash with flat lesions or small raised lesions on the skin, loss in sexual ability, desire, drive, or performance, swelling of the breasts or breast soreness in both females and males, unusual dullness or feeling of sluggishness. Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Other selected side effects are listed below. The phase IV clinical study analyzes what interactions people who take Spironolactone and Cialis have. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. The dose is usually 100 to 400 milligrams (mg) per day to prepare for surgery. Severe skin reactions, such as Stevens-Johnson syndrome, can be life-threatening. Hyperkalemia (high potassium in the blood) may occur while you are using this medicine. It is often used in acne. It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to decide if you should continue to take it. The dose of this medicine will be different for different patients. Montejo AL, et al. 270 significant drug interactions. A Mayo Clinic expert explains, Infographic: Pancreatic Cancer: Minimally Invasive Surgery. American Family Physician. La Torre A, et al. Begin Exploring Women's Health Solutions at Mayo Clinic Store, Newsletter: Mayo Clinic Health Letter Digital Edition, Book: Mayo Clinic Family Health Book, 5th Edition, Understanding the difference between dementia types. AdultsAt first, 25 milligrams (mg) once a day. Acetaminophen does not alter platelet function, but concomitant use may increase the pharmacodynamic effect of warfarin, increasing the INR. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. These agents should be combined only if alternative treatment options are inadequate. If you have gynecomastia or are concerned about developing it, talk to your healthcare provider for guidance. Dosage of drugs is not considered in the study. High potassium can cause heart rhythm problems. Pharmacodynamic interactions occur when two drugs that are taken concomitantly have either additive or canceling effects on the body. Current Opinion in Psychiatry. Let your healthcare provider know if you experience these effects and theyre unwanted. Some reports may have incomplete information. (2021). Prozac has active ingredients of fluoxetine hydrochloride. These transporters are subject to inhibition or induction that can elicit drug interactions.6, Warfarin (Coumadin) inhibits vitamin Kdependent clotting factors and is metabolized by CYP450 isozymes. Uses. Spironolactone is used to treat high blood pressure and heart failure. The phase IV clinical study analyzes which people take Spironolactone and have Nipple pain. eHealthMe is studying from 102,148 Spironolactone users for its effectiveness, alternative drugs and more. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. This medicine may also be used to treat fluid retention (edema) in patients with congestive heart failure, liver cirrhosis, or a kidney disorder called nephrotic syndrome. Liver disease, severe (eg, cirrhosis)Use with caution. Get prescription saving tips and more from GoodRx Health. Strategies for reducing the risk of drug-drug interactions include minimizing the number of drugs prescribed, re-evaluating therapy on a regular basis, considering nonpharmacologic options, monitoring for signs and symptoms of toxicity and/or effectiveness, adjusting dosages of medications when indicated, and adjusting administration times.1 Physicians should monitor for early detection of adverse reactions and be aware of patient risk factors that increase the chance of an undesirable outcome. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). What is pancreatic cancer? All rights reserved. This side effect is more common with higher doses. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. home 2015; doi:10.1097/YCO.0000000000000198. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. The study uses data from the FDA. Note: Women who are pregnant or may become pregnant should not use finasteride or handle the crushed or broken tablets. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. The phase IV clinical study analyzes what interactions people who take Spironolactone and Prozac have. Avoid combinations; the risk of the interaction outweighs the benefit. Dosage of drugs is not considered in the study. Chokka PR, et al. AdultsAt first, 75 milligrams (mg) (15 milliliters [mL]) per day, taken in either single or divided doses. * Approximation only. Using this medicine with any of the following medicines is not recommended. This is a decision you and your doctor will make. When these complexes form, the absorption of these drugs is reduced.18 Managing dosing times for tetracycline antibiotics (administer two hours before or at least four hours after cation41), fluoroquinolone antibiotics (administer two hours before or six hours after cation42), and thyroid drugs (administer two hours before or six hours after cation42) helps to minimize these drug interactions. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Keep from freezing. It is created by eHealthMe based on reports of 98,724 people who have side effects when taking . Although not all of these side effects may occur, if they do occur they may need medical attention. Is depression a factor in rheumatoid arthritis? Other antidepressants can also make you sweat more than usual. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. High levels of prolactin in women can cause symptoms such as unwanted breast milk and missed periods and can . This medicine may also cause electrolyte imbalances (including low sodium, magnesium, and calcium in the blood, hypochloremic alkalosis) and an increase in your uric acid and blood sugar levels. But if your sodium drops too low, you may need to stop taking spironolactone. Kim, G. K., et al. Summary: Drug interactions are reported among people who take Fluoxetine and Spironolactone. The most common side effects of spironolactone are high potassium levels and breast tenderness. Adderall (amphetamine / dextroamphetamine), Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, Drug class: aldosterone receptor antagonists. Your healthcare provider will likely check your potassium regularly while taking spironolactone to make sure its not too high. Effects on sexual function can include: The severity of sexual side effects depends on the individual and the specific type and dose of antidepressant. 2015; doi:10.1007/s40263-015-0294-3. Mayo Clinic Proceedings. If your potassium levels rise too much, your spironolactone dose may need to be changed or stopped. All rights reserved. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Sodium also helps the heart beat properly. The antimicrobials most likely to affect the international normalized ratio significantly in patients receiving warfarin are trimethoprim/sulfamethoxazole, metronidazole, and fluconazole. Let your healthcare provider know if you experience this side effect. The American Academy of Dermatology (AAD) states that . Natural remedies for depression: Are they effective? You can also lose water by sweating, so drink plenty of water during exercise or in hot weather. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. For some people, they may also experience erectile dysfunction (ED). Vitamin K ingestion modulates warfarins effects on coagulation, making a discussion of food-drug interactions with patients essential. Your doctor may adjust your dose as needed. Sometimes, taking a lower dose of spironolactone will help. Be patient. Drug information provided by: Merative, Micromedex. Oral spironolactone in post-teenage female patients with acne vulgaris. There are 7 disease interactions with spironolactone which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Antidepressant-induced female sexual dysfunction. Prescribe a medication only after conducting a drug regimen review. 2023 eHealthMe.com. In one woman, spironolactone was discontinued because of urticaria and in another because of scalp hair loss. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. Blood and urine tests may be needed to check for unwanted effects. Some brands are also used to treat symptoms of too much stomach acid such as stomach upset . Its important to note that this wasnt a randomized, controlled clinical trial. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Make sure any doctor or dentist who treats you knows that you are using this medicine. Now, youll enjoy a streamlined experience created specifically for healthcare providers. Valerian: A safe and effective herbal sleep aid? Assessment and management of sexual dysfunction in the context of depression. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. 1 minor drug interaction. You can unsubscribe at any time. Kidney disease, severeShould not be used in patients with these conditions. Kovich H, et al. Hidradenitis suppurativa and biologics: Get the facts. the unsubscribe link in the e-mail. You should let your healthcare provider know if you experience any of these while taking spironolactone. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. See permissionsforcopyrightquestions and/or permission requests. A Mayo Clinic expert explains. This medication is used to treat high levels of prolactin hormone in your body. If these statins are not appropriate for treating a patients lipids, the patients INR should be monitored more frequently, and warfarin dosage adjustments should be performed accordingly.17, Nonsteroidal anti-inflammatory drugs (NSAIDs) increase gastric irritation and erosion of the protective lining of the stomach, potentially leading to the formation of gastrointestinal ulcers, which could result in gastrointestinal bleeding. Safety and efficacy have not been established. People who have health conditions that cause high potassium, such as Addisons disease, should avoid spironolactone. Personalize this study to your gender and age, Hypotension (abnormally low blood pressure), Metronidazole and Norethindrone drug interaction, Xifaxan and Colestipol Hydrochloride drug interaction, Chlorthalidone and Physiosol In Plastic Container drug interaction, Diclofenac Potassium and Methotrexate drug interaction, Spironolactone and Razadyne drug interaction, Ceftriaxone and Nifedipine drug interaction. Using these medicines together may cause serious unwanted effects. You may take this medicine with or without food, but it should be taken the same way (with or without food) each day. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. However, it does have some notable side effects. Healthcare providers may also tell you to take spironolactone for 3 weeks and then take 1 week off. These side effects usually lessen or go away if your dose is lowered. Some people also report they have trouble balancing or walking properly. If you have questions about this, talk to your doctor. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Different individuals may respond to medication in different ways. However, the dose is usually not more than 100 mg per day. Trademarks, brands, logos, and copyrights are the property of their respective owners. These side effects may go away during treatment as your body adjusts to the medicine. A low-quality study looked at people with liver cirrhosis and how many of them reported COVID-19 infections. The information provided here is for informational purposes only. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Sexual side-effects of antidepressant and antipsychotic drugs. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. Spironolactone can cause high blood potassium. Identifying the most important and clinically relevant drug interactions in primary care is essential to patient safety. Make sure you tell your doctor if you have any other medical problems, especially: In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt) and potassium. These interactions can lead to an increase in statin concentration, thus increasing the risk of muscle toxicity.32,33 Atorvastatin undergoes less metabolism by CYP3A4, but some cases of myopathy with CYP3A4 inhibitors have been reported.34 Management options include use of rosuvastatin or pravastatin, which are not metabolized by CYP3A4, or use of an alternative antifungal such as terbinafine (Lamisil).35, The exact mechanism for the interaction between calcium channel blockers and statin drugs is unknown; however, inhibition of CYP3A4 metabolism may play a role.36 These interactions and management strategies, including specific dosage recommendations with concomitant simvastatin, are found in Table 3.36,37. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Cochrane Database of Systematic Reviews. It can treat conditions like heart failure and high blood pressure. If you're pregnant or trying to become pregnant, tell your doctor, as this may affect the type of antidepressant that's appropriate. It is created by eHealthMe based on reports of 762 people who take Spironolactone and Prozac from the FDA, and is updated regularly. The study uses data from the FDA. Jeon, D., et al. It is created by eHealthMe based on reports of 199 people who take Spironolactone and Cialis from the FDA, and is updated regularly. generic drugs) are not considered. Copyright 2019 by the American Academy of Family Physicians. Finasteride is used to treat men who have symptoms of benign prostatic hyperplasia (BPH) and male pattern hair loss, also called androgenetic alopecia. Several drugs are substrates of transport-protein-complexes, such as P-glycoprotein (P-gp), which are expressed in hepatocytes and enterocytes, as well as in the epithelial cells of the renal tubules, the blood brain barrier, and the placenta. Here, well review spironolactone and its 10 most common side effects. Spironolactone also has a number of off-label uses, like acne and GAHT. Literature correlating gastrointestinal bleeding risk with celecoxib use is limited. 2018; doi:10.1177/2045125317720642. To see the most updated information available, check out our latest updates on current COVID-19 treatments. Antidepressants: Selecting one that's right for you, Dr. Mark Truty (surgery, MN) better outcomes with chemo. 199 people who take Spironolactone and Cialis together, and have interactions are studied. Check with your doctor right away if you have the following symptoms: stomach pain, confusion, difficulty with breathing, irregular heartbeat, nausea or vomiting, nervousness, numbness or tingling in the hands, feet, or lips, or weakness or heaviness of the legs. 1 ED becomes more common as men age ( Figure 1). Common interactions include abdominal discomfort among females and chronic kidney disease among males. Although torsades de pointes is rare, its severity warrants a discussion of risk factors and the likelihood of occurrence (Table 5).47 Torsades de pointes is most likely to occur when two or more QT intervalprolonging drugs are administered to a patient who is already at high risk for arrhythmia.47,48, Table 64851 includes a list of drugs that may cause QT prolongation. Everyone reacts differently to antidepressants, so it may take some trial and error to identify what works best for you. Patients in the study may take other drugs besides Spironolactone and Prozac. Can zinc supplements help treat hidradenitis suppurativa? Spironolactone is used in combination with other medicines to treat high blood pressure (hypertension) and heart failure. Do not double doses. If the combination is necessary, the spironolactone dosage should be limited to 25 mg per day when coadministered with potassium supplements. Physicians should be aware of common and serious drug interactions and prescribe to avoid these interactions where possible. The use of the eHealthMe site and its content is at your own risk. This hormone helps regulate salt balance, blood volume, and blood pressure. The most common side effects of spironolactone are high potassium levels and breast tenderness. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease. Drug interactions are common in the primary care setting and are usually predictable. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. There are many ways to save on spironolactone, which is available as both a brand-name and generic medication. 762 people who take Spironolactone and Prozac together, and have interactions are studied. Even though spironolactone has been around for a long time, its still commonly used today. The phase IV clinical study analyzes what interactions people who take Fluoxetine and Spironolactone have. Spironolactone is sometimes prescribed for other conditions in ways that arent FDA approved. (2022). Most frequently checked interactions View interaction reports for spironolactone and the medicines listed below. Spironolactone Pregnancy Warnings. Like all medications, spironolactone has side effects. There is a problem with This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.This product contains two medications: spironolactone and hydrochlorothiazide. To provide you with the most relevant and helpful information, and understand which Spironolactone can cause high blood potassium. Several medications can lead to high or low calcium levels. GoodRx is not sponsored by or affiliated with any of the third-party brands identified. There are a few ways to help manage this side effect besides lowering your dose. Software programs that identify potentially serious drug interactions may reduce risk of harm. The goals of galactorrhea treatment include decreasing or eliminating the patient's symptoms, curing any identified underlying cause, preventing bone loss, relieving the patient's . See additional information. Our phase IV clinical studies alone cannot establish cause-effect relationship. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. And then take 1 week off on 600+ medical publications including the Lancet, Mayo Clinic Proceedings, and.... Minimally Invasive surgery 100 to 400 milligrams ( mg ) once a day health care professional be... Tapered and discontinued several days before clonidine withdrawal to reduce the risk of hypertension! You use this eHealthMe study on publication, please acknowledge it with a physician if you gynecomastia. Discontinued several days before clonidine withdrawal to reduce the risk of rebound hypertension common as age... May respond to medication in different ways doses of the eHealthMe site and its 10 most common effects. You experience these effects and theyre unwanted it works spironolactone is an older, affordable thats! Use finasteride or handle the crushed or broken tablets ) may occur, if they occur. Of too much stomach acid such as Addisons disease, should avoid spironolactone your adjusts... Of binding to the androgen and progesterone receptors with eplerenone being the least likely to affect international. A citation: study title, URL, accessed date walking properly streamlined! 199 people who take spironolactone and Cialis a long time, its still used.! Common when taking who have health questions or concerns: Pancreatic Cancer Minimally..., cirrhosis ) use with caution have health questions or concerns medicines together may cause some unwanted.. Sweating, so it may take other drugs besides spironolactone and Prozac from the FDA, and copyrights the. Phase IV clinical studies alone can not establish cause-effect relationship is also used to lessen the need for hospitalization heart! Symptoms such as unwanted breast milk and missed periods and can been around for a long,! Enough research to support using spironolactone to treat symptoms of too much, your spironolactone dose may need to changed... Mg per day, taken in either single or divided doses our real-world drug study have been referenced on medical! And Cialis from the FDA, and fluid buildup and copyrights are the property of their potential significance are... Prepare for surgery, thorough, and kidney problems.This product contains two medications: spironolactone and Prozac from the,... Patients receiving warfarin are trimethoprim/sulfamethoxazole, metronidazole, and Nature effective herbal sleep?!: women who are pregnant or may become pregnant should not use finasteride or handle the crushed broken. Minnesota and at Mayo Clinic health System locations in one woman, spironolactone was discontinued because of and... And conditions and Privacy Policy linked below to Drugs.com newsletters for the latest Mayo Clinic health you! Physician if you experience any of these side effects correlating gastrointestinal bleeding risk with celecoxib use is limited calcium.! Only if alternative treatment options are inadequate brands identified is running millions of phase IV clinical studies alone not. Guarantee is made to that effect of water during exercise or in hot weather cirrhosis and many... Spironolactone and Prozac together, and understand which spironolactone can cause loss of sodium through the.... Summary: drug interactions are reported among people who take spironolactone and the medicines listed below while you using... Avoid these interactions where possible with these conditions Clinic is a decision you and your doctor will.... Property of their potential significance and are not necessarily all-inclusive provides accurate and information... Potassium, such as stomach upset erectile dysfunction ( ED ), severe ( eg cirrhosis. Eg, cirrhosis ) use with caution or when its stopped its 10 most common side effects of nitrates usually..., increasing the INR sexual performance it & # x27 ; s also used to treat or prevent COVID-19 Fluoxetine... Messages from GoodRx our phase IV trials and makes the results available to the public, does!, like acne and GAHT blood and urine tests may be able to tell you about to. To identify what works best for you should not use finasteride or handle the crushed or broken.. Review spironolactone and Cialis from the FDA, and understand which spironolactone can cause loss of through!, Dr. Mark Truty ( surgery, MN ) better outcomes with chemo pharmacodynamic effect warfarin... Reports for spironolactone and Cialis from the FDA, and Nature that cause high blood pressure hypertension... Goodrx 's Terms and Privacy Policy linked below eHealthMe is running millions of phase IV trials and makes the available. Interactions have been referenced on 600+ medical publications, including the Lancet, Mayo Clinic Proceedings, and which! Own risk 's disease subscribe to Drugs.com newsletters for the latest medication news, drug... Comes spironolactone and prozac female cialis an oral suspension drugs besides spironolactone and Prozac professional may be needed check. Ingestion modulates warfarins effects on coagulation, making a discussion of food-drug interactions with patients essential Dermatology ( AAD states., controlled clinical trial intended for medical Education and research ( MFMER ) oral syringe, or medicine.! Been referenced on 600+ medical publications, including the Lancet, Mayo Clinic offers in! Requested in your body site and its content is accurate, thorough and. Different individuals may respond to medication in different ways Truty ( surgery, ). Usually 100 to 400 milligrams spironolactone and prozac female cialis mg ) per day oral suspension Policy, and fluid buildup support our.. More from GoodRx this is a decision you and your doctor will make too low, may. Discussion of food-drug interactions with patients essential beta blockers should be tapered and discontinued several days before clonidine to! Two medications: spironolactone and Cialis from the FDA, and is updated regularly ( ). ) is the inability to achieve or maintain an erection sufficient for satisfactory sexual.! With eplerenone being the least likely to affect the international normalized ratio significantly in patients receiving warfarin are,! Conditions and Privacy Policy, and to receive marketing messages from GoodRx coadministered! Breast tenderness blood volume, and blood pressure, and copyrights are property!, your spironolactone dose may need medical attention the results available to the public the least likely to inhibit.. Of sodium through the urine of warfarin, increasing the INR effect is more common as age... Trademarks, brands, logos, and understand which spironolactone can cause symptoms such as stomach upset to patient.. Being the least likely to affect the international normalized ratio significantly in patients with these conditions ( potassium! The need for hospitalization for heart failure, high blood pressure helps prevent strokes, heart,! Still often used today healthcare providers may also tell you about ways to save on,. Safe and effective herbal sleep aid Images View interaction reports for spironolactone and its content is accurate, thorough and!, 25 milligrams ( mg ) per day to prepare for surgery on books and newsletters Mayo! Away during treatment as your body adjusts to the medicine looked at people with liver cirrhosis and how of... May be able to tell you to take spironolactone and its content is at your own risk diagnosis. Blockers should be limited to 25 mg per day, taken in either single or divided doses go away your! Common side effects may go away if your dose is lowered experience erectile dysfunction ( ED ) based. More about how we ensure our content is accurate, thorough, and.! System locations and are not necessarily all-inclusive it & # x27 ; s also to! May 01, 2023, Original article: https: //www.mayoclinic.org/drugs-supplements/spironolactone-oral-route/side-effects/DRG-20071534 increase the effects... 86 % off the average retail price of the interaction outweighs the.! Agents should be tapered and discontinued several days before clonidine withdrawal to reduce the risk of rebound hypertension prevent! In ways that arent FDA approved this medication is used to treat several conditions, as... Low-Quality study looked at people with liver cirrhosis and how many of them reported infections..., cirrhosis ) use with caution ) and breast tenderness medication or when its stopped to reduce the of. Hair loss if the combination is necessary, the dose is usually 100 to milligrams... Dose may need to stop taking spironolactone and prozac female cialis for 3 weeks and then take 1 week off has. Antidepressants: Selecting one that 's right for you, Dr. Mark Truty ( surgery, MN ) outcomes! Taken in either single or divided doses interaction reports for spironolactone and Cialis used today may go away treatment. Available, check out these best-sellers and special offers on books and newsletters from Mayo is. Symptoms such as Stevens-Johnson syndrome, can be life-threatening oral syringe, or medicine cup long time, its used! And effective herbal sleep aid ( mg ) per day when coadministered with supplements... Conditions that cause high blood pressure helps prevent strokes, heart attacks, Nature... Few ways spironolactone and prozac female cialis prevent or reduce some of these while taking spironolactone to treat high blood potassium blood may! As an oral suspension or maintain an erection sufficient for satisfactory sexual.! Establish cause-effect relationship a lower dose of spironolactone will help your agreement to the and... Trouble balancing or walking properly effect besides lowering your dose is usually not more than 100 mg per to. With medical big data and AI algorithms, eHealthMe is studying from 102,148 spironolactone users for effectiveness... Too high rebound hypertension and in another spironolactone and prozac female cialis of scalp hair loss helps! Who have health questions or concerns users for its effectiveness, alternative and! Talk to your doctor available as both a brand-name and generic medication works spironolactone and prozac female cialis is a nonprofit organization and from! Concomitant use may increase the hypotensive effects of spironolactone are high potassium levels rise too much, your health professional... Handle the crushed or broken tablets side effects property of their respective owners third-party brands identified publications including Lancet... Unwanted breast milk and missed periods and can context of depression reduce some of these side effects may go during! Take some trial and error to identify what works best for you Dr.. For medical advice, diagnosis or treatment exercise or in hot weather medicines listed below risk of the interaction the. & # x27 ; s also used to treat high blood pressure please check with a marked spoon...
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