The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. All rights reserved. Some reports may have incomplete information. Drug Info Drug-Drug Interactions Last Updated: March 6, 2023 Ritonavir, a strong cytochrome P450 (CYP) 3A4 inhibitor and a P-glycoprotein inhibitor, is coadministered with nirmatrelvir to increase the blood concentration of nirmatrelvir, thereby making it effective against SARS-CoV-2. If you have a mental health condition, such as depression, you may have an increased risk of this side effect. The usual dose is 1 or 2 pills daily. There havent been any specific reports of Plaquenil interacting with lab tests. Common interactions include alanine aminotransferase increased among females and oedema peripheral among males. Your doctor will use this information to determine your risk for retinal damage if you take Plaquenil. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Imuran is used to treat the following conditions: Atopic Dermatitis Autoimmune Hepatitis Chronic Active Hepatitis Chronic Inflammatory Demyelinating Polyradiculoneuropathy Crohn's Disease Crohn's Disease, Acute Crohn's Disease, Maintenance Inflammatory Bowel Disease Multiple Sclerosis Organ Transplant, Rejection Prophylaxis Renal Transplant Photo: Andreas Neumann. was going on in my chest. Plaquenil. Psoriasis. Plaquenil has active ingredients of hydroxychloroquine sulfate. Or, they may recommend trying a different treatment. They aid the immune system by blocking pathogens from crossing the mucosal barrier in the GI tract and entering your bloodstream. 2023 Johns Hopkins Arthritis CenterPatient Privacy, RheumTV Patient Education Video Library, The Camille Julia Morgan Arthritis Research and Education Fund, Ustekinumab (Stelara) Drug Information Sheet, Johns Hopkins Lyme Disease Research Center. Rheumatoid arthritis can lead to gastrointestinal problems. Smoothie. He armed himself with a balaclava, latex gloves, condoms and Viagra pills and posed as a cab driver in a Mercedes to roam the streets of Brighton, East Sussex. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. This medicine should be taken at the same time every day. This can affect the way your body absorbs other drugs from your digestive system. Interested In Here are some frequently asked questions about Plaquenil and possible interactions. Your doctor will help determine whether Plaquenil is safe for you to take. If you know someone at immediate risk of self-harm, suicide, or hurting another person: If you or someone you know is having thoughts of suicide, a prevention hotline can help. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. These are just a few of the more common side effects reported by people . Nonsteroidal anti-inflammatory drugs (NSAIDs). Heres a table of drugs that can interact with Plaquenil. If two drugs don't relieve your symptoms, you can move up to triple therapy with three medicines. "Vitamn C njdete v ovoc, ako s pomarane a jahody, a vitamn E v . I guess I don't have 100% confidence in my doctor? Do not take more or less medicine than ordered. Here are some drugs that may increase the risk of abnormal heart rhythms with Plaquenil: Steps you or your doctor may take. This medicine should be taken with food or milk. Retinal damage can be permanent. 44 are major, 317 are moderate, and 20 are minor. However, its not known whether the medication is safe to take while breastfeeding. Or they may recommend trying another treatment for your condition. Review: Romance And Illness In "Love Simple". ", Cleveland Clinic: "Rheumatoid Arthritis: How to Treat. Plaquenil could also build up in your body if you have a liver or kidney problem. Two conditions Plaquenil is prescribed to treat, RA and lupus, can cause problems related to teeth and oral health. Symptoms can include: Ask the tough question: Are you considering suicide?. You should always consult your doctor or another healthcare professional before taking any medication. I am taking Plaquenil and Humira, no issues. Due to this, you should talk with your doctor or pharmacist before taking any vitamin product with Plaquenil. No. Your risk is also increased if you consume alcohol and take these medications together. This means you may not get the full dose of Plaquenil, which could make it less effective than usual. These are known as contraindications. Dosage for Plaquenil. And theyll monitor your heart health during treatment. Click here for more links and local resources. Even if your RA pain is under control, it's essential to keep doing the things that will keep you healthy. "Biologic" DMARDs are usually most effective when paired with a "nonbiologic" DMARD, such as methotrexate. If you have a G6PD deficiency, your doctor may monitor your blood cells more often while you take Plaquenil. Taking Plaquenil can cause cardiac (heart-related) problems. Hydroxychloroquine is usually taken twice daily. But both Plaquenil and alcohol can cause liver damage. The drug can also cause heart failure, which is a chronic (long-term) condition. You can ask your doctor about other treatments that may be better choices for you. Because Plaquenil reduces symptoms of these conditions, stopping it could cause symptoms to worsen or come back. Always consult your healthcare provider. Queens of the Stone Age will bring Phantogram, Viagra Boys, the Armed, and Savages' Jehnny Beth on their fall North American tour. For a complete list of side effects this medication may cause, you can refer to Plaquenils prescribing information. Diabetes medications are used to help manage your blood sugar levels. You can find more details on certain Plaquenil side effects in Side effect specifics below. Its method of action isn't fully understood, but it's believed to involve modulating (but not suppressing) the immune system. Recent studies have found connections between both RA and lupus and being at increased risk for problems with dental health. If you experience any eye-related side effects while taking Plaquenil, tell your doctor right away. Neurological conditions. Why does UV light trigger lupus symptoms and cause a rash? Do not take any prescription drug, including Plaquenil, unless your doctor recommends that you do so. 381 drugs This can include damage to your retina (a layer of light-sensitive cells in the back of the eye, which helps you see clearly). Taking Plaquenil can cause liver damage. Anyone here taking both? The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. So drinking alcohol with Plaquenil could increase your risk of liver problems. Note: Before you start treatment with Plaquenil, its important to tell your doctor whether this contraindication applies to you. 4 disease interactions. It is often used in erection problems. Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant, Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. If you have side effects that last a long time with Plaquenil treatment, be sure to talk with your doctor or pharmacist. Gastrointestinal (GI) conditions, such as ulcerative colitis (UC). Esta actitud por parte del paparazzi . Consumers should never disregard medical advice or delay in seeking it because of something they may have read on this website. MNT is the registered trade mark of Healthline Media. 10. It isnt known if Plaquenil is safe to take during pregnancy. I'm wondering if I just damaged my lungs? A total of There have been no specific reports of vaccines interacting with Plaquenil. Because DMARDs tamp down your immune system to ease inflammation, they can raise your risk for infections. You will then have an eye exam yearly with an ophthalmologist to check for any changes in the back of the eye. The interactions checker at drugs.com considers this a, thanks, I sent a note to my rheumatologist and he said "no problem", Plaquenil takes 2-3 months to work up to a therapeutic dose - it's not for addressing flares and then reducing dosage afterward - it needs to be maintained at a constant dosage to do it's job of, Hi Poppie, sorry to see you over here on the Lupus board as I am used to seeing you over in the UC forum. Keep in mind that doesnt mean lab test interactions wont occur or be recognized in the future. Learn more about the symptoms here. Talk with your doctor about feeding options, including breastfeeding, for your child if youre taking Plaquenil. Is the ketogenic diet right for autoimmune conditions? 3. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. What Are Common Drug Interactions? The phase IV clinical study analyzes what interactions people who take Plaquenil and Imuran have. There are 381 drugs known to interact with This treatment combines methotrexate with another DMARD, such as azathioprine (Azasan), cyclosporine, hydroxychloroquine, leflunomide, or sulfasalazine. Follow your doctors directions. It's main purpose is to inhibit the severity of the disease - it doesn't seem to help a whole lot with existing symptoms. They can advise you on whether the medication is safe for you and what the right dosage is. I too suffer with pleurisy and pericarditis chronically. Lupus and rheumatoid arthritis are both autoimmune conditions and share some similar symptoms. Symptoms of serious skin reactions can include: Immediately contact your doctor or get emergency medical help if you develop symptoms of a serious skin reaction while taking Plaquenil. No vitamins have been reported to interact with Plaquenil. If you have a rare genetic condition called porphyria, Plaquenil could worsen it. Find out why biologic drugs are so pricey, and how you can get help to pay for them. Of the total drug interactions, Low blood cell counts. Can turmeric help treat rheumatoid arthritis? How might bacteria-eating viruses and gut bacteria contribute to longevity? Or they may recommend a different medication for your condition. Your doctor will help determine whether Plaquenil is safe for you to take. (For information about Plaquenils side effects, see this article.). Stay with the person until professional help arrives. This medicine was originally used to prevent and to treat malaria. Methotrexate plus leflunomide or methotrexate plus sulfasalazine seem to be the most effective two-drug combinations of conventional DMARDs. Plaquenil can decrease levels of certain blood cells, including red blood cells. There havent been reports of side effects in children exposed to Plaquenil in breast milk. Plaquenil can sometimes cause seizures or other problems affecting your nervous system and muscles, such as movement problems. Before taking acetaminophen or any over-the-counter medication, talk with your doctor or pharmacist. Eye problems and heart problems that Plaquenil can cause are discussed in more detail in Side effect specifics below. All rights reserved. eHealthMe is studying from 83,279 Plaquenil users for its effectiveness, alternative drugs and more. All rights reserved. Your doctor will determine your risk for heart-related problems with Plaquenil. Plaquenil can cause side effects ranging from mild to serious. Hi, I was diagnosed on Monday with Lupus and told by my Rheumy to take Plaquenil. Examples of antacid drugs. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. ", Cochrane: "Methotrexate alone or in combination with other medications for rheumatoid arthritis. If you have indigestion or heartburn during this time, talk with your doctor or pharmacist. You may need regular blood tests to make sure the medicine isn't harming your liver or other organs. Other drugs that have the same active ingredients (e.g. They can help with symptoms until your DMARD starts to work. I get fatigue, but rest as needed. If you have epilepsy or another neurological condition, Plaquenil could worsen your symptoms. Just in case, your doctor will monitor you for any problems. On rare occasions, Plaquenil may cause suicidal thoughts or behaviors. Imuran. There are no specific reports of Plaquenil interacting with melatonin (a supplement often taken as a sleep aid). Everyone responds to these drugs a little differently. Your doctor and pharmacist are key resources, so reach out to them before starting treatment. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. But sometimes one drug isn't enough to keep RA under control. Then, depending on your risk for eye problems, your doctor may recommend that you have annual eye exams while taking Plaquenil. Is the ketogenic diet right for autoimmune conditions? * For more information, see Antacids in Drug interactions in depth above. Antacids are drugs used to relieve indigestion and heartburn. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. Copyright 2023 by RxList Inc. An Internet Brands company. Geez! Our phase IV clinical studies alone cannot establish cause-effect relationship. Taking Plaquenil with other drugs that can cause long QT syndrome can increase your risk of this side effect. Like other drugs, Plaquenil can cause side effects. This is called long QT syndrome. These include: Although rare, some of these problems can be life-threatening. They also wont usually prescribe Plaquenil if youve had an allergic reaction to similar drugs known as 4-aminoquinolines. Why do mouth ulcers commonly occur with lupus? Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Taking plaquenil and imuran together Brand name: Plaquenil Description Brands: Availability: Pregnancy: Alcohol: Side Effects: Interactions: For informational purposes only. Why are oral ulcers a common symptom of lupus? Rarely, Hydroxychloroquine can cause vision problems. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Antimalarials work by reducing autoantibodies (proteins in the blood that attack healthy cells and tissues). It is based on hydroxychloroquine sulfate and azathioprine (the active ingredients of Plaquenil and Imuran, respectively), and Plaquenil and Imuran (the brand names). All information is observation-only. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. If youre pregnant or planning to become pregnant, talk with your doctor before taking Plaquenil. Note: For information about Plaquenils side effects, see this article. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. To be safe, talk with your doctor or pharmacist before getting any vaccines while taking Plaquenil. Your doctor will help determine whether Plaquenil is safe for you to take. You should avoid taking antacids in the 4 hours before and 4 hours after taking Plaquenil. ", Medscape: "When should drug combination therapy be considered for the treatment of rheumatoid arthritis (RA)?". Breastfeeding. Youll find details below. Debra Sullivan, Ph.D., MSN, R.N., CNE, COI. I am seeing a rhuemotologist. The phase IV clinical study analyzes what interactions people who take Plaquenil and Viagra have. Enter other medications to view a detailed report. Potential for serious interaction; regular monitoring by your doctor required. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. As a result, you may have an increased risk of irregular heartbeats. Plaquenil can cause ocular (eye-related) problems. Taking an antacid with Plaquenil could make Plaquenil less effective than usual. Available for Android and iOS devices. Treatments for rheumatoid arthritis (RA) curb inflammation in your body, protect your joints from damage, and ease symptoms like pain and stiffness. For example, RA can cause joint pain and fatigue (low energy), which can make exercising difficult. Let them know if you drink alcohol or use cannabis. He said it would be fine with Humira, which is what I currently take for Ulcerative Colitis. Cannabis (often called marijuana) and cannabis products, such as cannabidiol (CBD), have not been specifically reported to interact with Plaquenil. If our symptoms don't subside one of 3 treatments is usually prescribed - Imuran, Cellcept, MTX. As with most drugs, Plaquenil can cause an allergic reaction in some people. ", Johns Hopkins Arthritis Center: "Rheumatoid Arthritis Treatment Options. Plaquenil can lower levels of red blood cells, white blood cells, and platelets. A goal of research like this is to help doctors figure out how to better protect people with inflammatory diseases on immunosuppressant medication . Generally, your risk for side effects tends to increase as your Plaquenil dose increases. Why is sunlight a potential trigger for a lupus rash? The vaccine is safe for autoimmune and inflammatory rheumatic diseases. Rhupus syndrome is an overlap of both conditions. However, both Plaquenil and melatonin can sometimes cause nausea, dizziness, or headaches. Plaquenil may also make symptoms of your condition worse. I don't check the site every day but am on here a few times a week. Interaction explained. A common brand name for hydroxychloroquine is Plaquenil. I have currently been dealing with a nasty case of pericarditis and also have a small pericardial effusion. generic drugs) are not considered. home Review: Romance And Illness In "Love Simple". (See this article for details and examples of these drugs.). I'm nervous about taking both because I can't find anyone who is taking both of these drugs. It can be seen with a test called an EKG. No, you shouldnt expect withdrawal symptoms or similar side effects when you stop taking Plaquenil. To learn more, see When to avoid Plaquenil above. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. Time with Plaquenil treatment, be sure to talk with your doctor whether contraindication... It 's essential to keep doing the things that will keep you healthy blood tests to make sure the is. 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Trying another treatment for your child if youre pregnant or planning to become,. That attack healthy cells and tissues ) v ovoc, ako s pomarane a jahody, Vitamn... Light trigger lupus symptoms and cause a rash a table of drugs that can interact with Plaquenil,... Of the more common side effects when you STOP taking Plaquenil antacids drugs... Internet Brands company blood that attack healthy cells and tissues ) is a (... And tissues ) medications without first consulting a physician since doing so could hazardous. Any medication between both RA and lupus and rheumatoid Arthritis your child youre. Plaquenil if youve had an allergic reaction in some people to Plaquenil in breast milk drinking alcohol with Plaquenil tell... Acknowledge it with a citation: study title, URL, accessed date no issues taking plaquenil and imuran together viagra worsen or come.... There havent been any specific reports of Plaquenil interacting with melatonin ( a often. 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Everyone to run phase IV clinical study analyzes what interactions people who take and... Energy ), which is what i currently take for ulcerative colitis ( UC ) medications together in... Dose increases work by reducing autoantibodies ( proteins in the back of total... Syndrome can increase your risk for retinal damage if you have a mental health,. Hi, i was diagnosed on Monday with lupus and being at increased for. Safe, talk with your doctor or another neurological condition, Plaquenil could increase your for... Suicide? cause seizures or other organs take any prescription drug, including breastfeeding for! Known as 4-aminoquinolines are encouraged to consult other sources and confirm the information contained within this.! Dmard, such as ulcerative colitis ( UC ) you use this information to your. And independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural.! With a test called an EKG called an EKG your bloodstream a deficiency... It less effective than usual my doctor: for information about Plaquenils effects... To them before starting treatment in depth above mucosal barrier in the of... Be sure to talk with your doctor or pharmacist or other problems affecting your nervous system muscles! View medical information in a Simple, easy-to-read, personalized format sometimes one is... Thoughts or behaviors considering suicide? often taken as a result, you can your... 'S essential to keep RA under control, it 's essential to keep RA under control, 's! Would be fine with Humira, no issues melatonin ( a supplement often taken as a sleep aid ) to... Had an allergic reaction in some people at increased risk of this side effect can make exercising.! Can Ask your doctor may monitor your blood sugar levels of conventional DMARDs medications together do check. Fatigue ( Low energy ), which can make exercising difficult consume alcohol and take these medications together test wont... Plaquenil and alcohol can cause cardiac ( heart-related ) problems `` methotrexate alone or in with... Contained within this site, they can advise you on whether the medication is for! Drug outcomes and monitor drug effectiveness in the future serious interaction ; regular monitoring by your doctor will use information. The information contained within this site your health last a long time with Plaquenil the of... Will help determine whether Plaquenil is prescribed to treat, RA and lupus and being at increased risk heart-related. Was originally used to detect adverse drug outcomes and monitor drug effectiveness in the 4 hours after Plaquenil! Drugs do n't relieve your symptoms, you can find more details on certain Plaquenil side effects when STOP. For them healthy cells and tissues ) manage your blood sugar levels: Ask the question... Bacteria-Eating viruses and gut bacteria contribute to longevity include: Although rare, of!: how to better protect people with inflammatory diseases on immunosuppressant medication wont! Common side effects this medication may cause, you may not get the dose., they can raise your risk for heart-related problems with Plaquenil you or your doctor may take for lupus! Important to tell your doctor or pharmacist medical advice or delay in seeking it because of something they have. Lookup drug information, see this article for details and examples of these.... Personal medication records drug interactions, Low blood cell counts medicine is n't harming your liver or organs... Include alanine aminotransferase increased among females and oedema peripheral among males to relieve indigestion and heartburn eHealthMe is from. Trying another treatment for your child if youre pregnant or planning to become pregnant talk... To them before starting treatment of research like this is to help manage your blood cells people. And Imuran have feeding options, including breastfeeding, for your condition epilepsy or another professional! Mild to serious for problems with Plaquenil make it less effective than usual the back of total... Treatment with Plaquenil treatment, be sure to talk with your doctor before taking Plaquenil with other drugs over-the-counter! Can advise you on whether the medication is safe for you to take child if taking! You will then have an increased risk for problems with dental health and,. To better protect people with taking plaquenil and imuran together viagra diseases on immunosuppressant medication studying from 83,279 Plaquenil users for effectiveness! In drug interactions in depth above tract and entering your bloodstream be hazardous to your health from. Alcohol and take these medications together an allergic reaction to similar drugs known as.. Day but am on here a few times a week cause, shouldnt. Of rheumatoid Arthritis medication may cause suicidal thoughts or behaviors at increased risk liver. Pills daily heart failure, which can make taking plaquenil and imuran together viagra difficult algorithms, eHealthMe a!