Created for people with ongoing healthcare needs but benefits everyone. For adults, doses up to 10 mg for smaller areas and up to 40 mg for larger areas have usually been sufficient. Alemtuzumab: (Moderate) Concomitant use of alemtuzumab with immunosuppressant doses of corticosteroids may increase the risk of immunosuppression. Corticosteroids stimulate hepatic glucose production and inhibit peripheral glucose uptake into muscle and fatty tissues, producing insulin resistance. Decreased insulin production may occur in the pancreas due to a direct effect on pancreatic beta cells. Nateglinide: (Moderate) Monitor patients receiving antidiabetic agents closely for worsening glycemic control when corticosteroids are instituted and for signs of hypoglycemia when corticosteroids are discontinued. Ceritinib: (Moderate) Ceritinib, a strong CYP3A4 inhibitor, may inhibit the CYP3A4 metabolism of triamcinolone, resulting in increased plasma triamcinolone concentrations and reduced serum cortisol concentrations. For potential or actual medical emergencies, immediately call 911 or your local emergency service. Corticosteroids can down-regulate somatostatin subtype 2 receptors: thereby, interfering with binding of gallium Ga 68 dotatate to malignant cells that overexpress these receptors. There have been reports of clinically significant drug interactions in patients receiving another strong CYP3A4 inhibitor with triamcinolone, resulting in systemic corticosteroid effects including, but not limited to, Cushing syndrome and adrenal suppression. Thank you doctors. Rare cases of death, primarily in preterm neonates, have been reported. Decreased insulin production may occur in the pancreas due to a direct effect on pancreatic beta cells. If systemic or inhaled glucocorticoid therapy is required, the steroid dose should be carefully adjusted and growth rate monitored. If it seems extremely hard to open, do not try to open it by force. Corticosteroids may increase blood glucose concentrations. Preparation:Use strict aseptic technique. Darunavir: (Moderate) Darunavir may inhibit the CYP3A4 metabolism of triamcinolone, resulting in increased plasma triamcinolone concentrations and reduced serum cortisol concentrations. Intensified electrolyte depletion, particularly hypokalemia, may occur. Pimozide: (Moderate) According to the manufacturer of pimozide, the drug should not be coadministered with drugs known to cause electrolyte imbalances, such as high-dose, systemic corticosteroid therapy. In patients receiving concomitant corticosteroids and chronic use of salicylates, withdrawal of corticosteroids may result in salicylism because corticosteroids enhance renal clearance of salicylates and their withdrawal is followed by return to normal rates of renal clearance. There have been reports of clinically significant drug interactions in patients receiving another strong CYP3A4 inhibitor with triamcinolone, resulting in systemic corticosteroid effects including, but not limited to, Cushing syndrome and adrenal suppression. Additive immune suppression may result from concomitant use of ponesimod and high-dose corticosteroid therapy which may extend the duration or severity of immune suppression. Butalbital is a CYP3A4 inducer; triamcinolone is a CYP3A4 substrate. Albiglutide: (Moderate) Monitor blood glucose during concomitant corticosteroid and incretin mimetic use; an incretin mimetic dose adjustment may be necessary. Activation of latent disease or exacerbation of intercurrent infection due to pathogens such as Amoeba, Candida, Cryptococcus, Mycobacterium, Nocardia, Pneumocystis, or Toxoplasma can occur in patients receiving systemic corticosteroids. Please tell me, could injection really remove hemorrhoids from my anus? Both corticosteroids and thiazide diuretics cause increased renal potassium loss. Corticosteroids may increase blood glucose concentrations. Both corticosteroids and thiazide diuretics cause increased renal potassium loss. Decreased insulin production may occur in the pancreas due to a direct effect on pancreatic beta cells. Both corticosteroids and thiazide diuretics cause increased renal potassium loss. Corticosteroid exposure is likely to be increased. Butalbital is a CYP3A4 inducer; triamcinolone is a CYP3A4 substrate. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. Fosphenytoin: (Moderate) Monitor for decreased corticosteroid efficacy if triamcinolone is used with fosphenytoin; a dosage increase may be necessary. Use the lowest possible dose in pediatric patients. Ensure the correct product has been chosen for use.Triamcinolone hexacetonide may be administered by intra-articular, intralesional, or sublesional injection.Use strict aseptic technique.To ensure a uniform suspension, shake vials well before use. Mannitol itself can cause hypernatremia. Thiazolidinediones: (Moderate) Monitor blood glucose during concomitant corticosteroid and thiazolidinedione use; a thiazolidinedione dose adjustment may be necessary. Warfarin: (Moderate) Monitor the INR if warfarin is administered with corticosteroids. Sodium Phosphate Monobasic Monohydrate; Sodium Phosphate Dibasic Anhydrous: (Moderate) Use sodium phosphate cautiously with corticosteroids, especially mineralocorticoids or corticotropin, ACTH, as concurrent use can cause hypernatremia. Psychiatric derangements may appear when corticosteroids are used, ranging from euphoria, insomnia, mood swings, personality changes, and severe depression, to frank psychosis. Corticosteroids stimulate hepatic glucose production and inhibit peripheral glucose uptake into muscle and fatty tissues, producing insulin resistance. Systemic and inhaled corticosteroids are known to increase blood glucose and worsen glycemic control in patients taking antidiabetic agents. Potassium-sparing diuretics: (Minor) The manufacturer of spironolactone lists corticosteroids as a potential drug that interacts with spironolactone. Risk factors for impaired glucose tolerance due to corticosteroids include the corticosteroid dose and duration of treatment. It is a high to very high potency steroid medicine which needs a doctors prescription and is only offered as a treatment form when the benefits outweigh the risks. Corticosteroids may increase blood glucose concentrations. In patients receiving concomitant corticosteroids and chronic use of salicylates, withdrawal of corticosteroids may result in salicylism because corticosteroids enhance renal clearance of salicylates and their withdrawal is followed by return to normal rates of renal clearance. Decreased insulin production may occur in the pancreas due to a direct effect on pancreatic beta cells. Clinical improvement or recovery after stopping therapy may require weeks to years. Max: 100 mg IM single dose. Clinical improvement or recovery after stopping therapy may require weeks to years. As with any long-term topical treatment of the nasal cavity, patients using nasal triamcinolone over several months or longer should be examined periodically for possible changes in the nasal mucosa. Use of these medications together may impact the accuracy of the macimorelin growth hormone test. Dosage not established. General dose range: 2.5 to 100 mg IM. Both corticosteroids and loop diuretics cause increased renal potassium loss. Consider the benefit-risk of concomitant use and monitor for systemic corticosteroid side effects. Usual dose range is 40 to 80 mg IM per day. Systemic triamcinolone is quickly distributed into the kidneys, intestines, skin, liver, and muscle. Decreased insulin production may occur in the pancreas due to a direct effect on pancreatic beta cells. In patients receiving concomitant corticosteroids and chronic use of salicylates, withdrawal of corticosteroids may result in salicylism because corticosteroids enhance renal clearance of salicylates and their withdrawal is followed by return to normal rates of renal clearance. Corticosteroids stimulate hepatic glucose production and inhibit peripheral glucose uptake into muscle and fatty tissues, producing insulin resistance. There is an enhanced effect due to decreased metabolism of systemic corticosteroids in patients with severe hepatic disease with cirrhosis. Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide: (Moderate) Cobicistat may inhibit the CYP3A4 metabolism of triamcinolone, resulting in increased plasma triamcinolone concentrations and reduced serum cortisol concentrations. being able to get an erection sometimes, but not every time you want to have sex. If signs of HPA suppression occur with the use of intranasal corticosteroids, the drug should be slowly discontinued. Triamcinolone topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. Titrate dose based on patient response and relief duration; usual dose range is 40 to 80 mg IM per day. Lopinavir; Ritonavir: (Moderate) Ritonavir may inhibit the CYP3A4 metabolism of triamcinolone, resulting in increased plasma triamcinolone concentrations and reduced serum cortisol concentrations. Clinical improvement or recovery after stopping therapy may require weeks to years. Once withdrawn, use immediately to prevent the suspension from settling in the syringe.For Trivaris: Attach a 27-gauge half-inch needle to the syringe, and advance the plunger to the single line marked on the prefilled glass syringe shaft. If corticosteroid therapy is to be discontinued, consider tapering the dose over a period of time to decrease the potential for withdrawal. Symptoms of ED include. In some patients, a corticosteroid dose adjustment may be needed. Do not store for later use.- Do not expose product to temperatures above 77 degrees F- Do not freeze- Reconstituted product must be used within 4 hours- Refrigerate (between 36 and 46 degrees F)- Store in carton- Unopened product may be stored at room temperature (68 to 77 degrees) for up to 6 weeks if not stored under refrigeration. It's used to treat allergic and autoimmune disorders like allergies, ulcerative colitis, psoriasis, eczema, arthritis, and many other conditions. Clinical improvement or recovery after stopping therapy may require weeks to years. Monitor for decreased response to triamcinolone during concurrent use. Triamcinolone use is not common; hydrocortisone and prednisone are more commonly given. An agglomerated product results from exposure to freezing temperatures and should not be used.After withdrawal from the vial, inject without delay to prevent settling of the injection in the syringe.Administration of triamcinolone via these routes require specialized techniques. If corticosteroid therapy is to be discontinued, consider tapering the dose over a period of time to decrease the potential for withdrawal. If corticosteroid therapy is to be discontinued, consider tapering the dose over a period of time to decrease the potential for withdrawal. Corticosteroids may increase blood glucose concentrations. In patients receiving concomitant corticosteroids and chronic use of salicylates, withdrawal of corticosteroids may result in salicylism because corticosteroids enhance renal clearance of salicylates and their withdrawal is followed by return to normal rates of renal clearance. Corticosteroids stimulate hepatic glucose production and inhibit peripheral glucose uptake into muscle and fatty tissues, producing insulin resistance. Decreased insulin production may occur in the pancreas due to a direct effect on pancreatic beta cells. Withdraw the full contents (32 mg) from the triamcinolone vial into the syringe, and remove the syringe from the vial adapter.To ensure the powder is suspended, gently invert the syringe several times prior to administration.Administer the entire contents of the syringe using usual technique for intra-articular injection. In some patients, a corticosteroid dose adjustment may be needed. Find a doctor. If corticosteroid therapy is to be discontinued, consider tapering the dose over a period of time to decrease the potential for withdrawal. Caffeine; Sodium Benzoate: (Moderate) Corticosteroids may cause protein breakdown, which could lead to elevated blood ammonia concentrations, especially in patients with an impaired ability to form urea. Consider the benefit-risk of concomitant use and monitor for systemic corticosteroid side effects. Risk factors for impaired glucose tolerance due to corticosteroids include the corticosteroid dose and duration of treatment. An acute myopathy has been observed with the use of high doses of corticosteroids in patients receiving concomitant long-term therapy with neuromuscular blockers. Amifampridine: (Moderate) Carefully consider the need for concomitant treatment with systemic corticosteroids and amifampridine, as coadministration may increase the risk of seizures. Systemic and inhaled corticosteroids are known to increase blood glucose and worsen glycemic control in patients taking antidiabetic agents. There have been reports of clinically significant drug interactions in patients receiving another strong CYP3A4 inhibitor with triamcinolone, resulting in systemic corticosteroid effects including, but not limited to, Cushing syndrome and adrenal suppression. Corticosteroids stimulate hepatic glucose production and inhibit peripheral glucose uptake into muscle and fatty tissues, producing insulin resistance. 0.11 to 1.6 mg/kg/day (3.2 to 48 mg/m2/day) IM divided in 3 or 4 doses for the treatment of severe conditions when oral treatment is not appropriate or feasible. In patients taking corticosteroids, voriconazole-associated CYP3A4 inhibition of their metabolism may lead to corticosteroid excess and adrenal suppression. Vigabatrin: (Major) Vigabatrin should not be used with corticosteroids, which are associated with serious ophthalmic effects (e.g., retinopathy or glaucoma) unless the benefit of treatment clearly outweighs the risks. Acetaminophen; Aspirin: (Moderate) Monitor for gastrointestinal toxicity during concurrent corticosteroid and salicylate use. Risk factors for impaired glucose tolerance due to corticosteroids include the corticosteroid dose and duration of treatment. The main risk factors for impaired glucose tolerance due to corticosteroids are the dose of steroid and duration of treatment. The main risk factors for impaired glucose tolerance due to corticosteroids are the dose of steroid and duration of treatment. For mouth sores, it is applied at bedtime and, if necessary, two or three times daily, preferably after meals. Oct 13, 2021. Cobicistat: (Moderate) Cobicistat may inhibit the CYP3A4 metabolism of triamcinolone, resulting in increased plasma triamcinolone concentrations and reduced serum cortisol concentrations. Intravitreal injectable suspension (Triesence or Trivaris)Triamcinolone acetonide injectable suspension may be administered by intravitreal injection.Administration via this route requires specialized techniques. In some patients, a corticosteroid dose adjustment may be needed. However, most dermatologists stress that topical corticosteroids can be safely used during lactation and breast-feeding. Corticosteroids may increase blood glucose concentrations. Corticosteroids should not be used in active ocular herpes simplex because of possible corneal perforation. Brompheniramine; Dextromethorphan; Phenylephrine: (Moderate) The therapeutic effect of phenylephrine may be increased in patient receiving corticosteroids, such as hydrocortisone. There have been reports of clinically significant drug interactions in patients receiving another strong CYP3A4 inhibitor with triamcinolone, resulting in systemic corticosteroid effects including, but not limited to, Cushing syndrome and adrenal suppression. Use systemic, nasal, intravitreal, and suprachoroidal corticosteroids with caution in patients with glaucoma; corticosteroids can cause increased intraocular pressure with possible damage to the optic nerves. Triamcinolone topical cream: Apply a small amount to the affected area(s) 2 to 3 times daily. Lipocortins, in turn, control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of the precursor molecule arachidonic acid. Both corticosteroids and thiazide diuretics cause increased renal potassium loss. (Moderate) Monitor blood glucose during concomitant corticosteroid and sulfonylurea use; a sulfonylurea dose adjustment may be necessary. Trianide Mild-Cream; Descriptions. Indicated routes of administration vary by formulation. Dexamethasone administration on long bone tissue in vitro resulted in a decrease of local synthesis of IGF-1. Consider the benefit-risk of concomitant use and monitor for systemic corticosteroid side effects. Methenamine; Sodium Salicylate: (Moderate) Monitor for gastrointestinal toxicity during concurrent corticosteroid and salicylate use. Therefore, drugs that induce potassium loss, such as corticosteroids, could counter the hyperkalemic effects of potassium-sparing diuretics. While rare, serious anaphylactoid events have occurred following the administration of parenteral triamcinolone acetonide or hexacetonide injections. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. Approximately 40% of the administered dose is excreted in the urine, and 60% in the feces, primarily as the metabolites. 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