Orlistat may decrease the effectiveness of Truvada. You should be confirmed that you are HIV-negative before you start using this medicine and you must stay HIV-negative to keep taking this medicine. Emtricitabine/tenofovir disoproxil fumarate used for a PrEP indication is only for HIV-negative individuals; status confirmed immediately prior to initiating and periodically during use. You can talk with your doctor about your risk of these side effects. Missing doses of Truvada makes it less effective at preventing HIV. If you have a kidney problem, such as chronic kidney disease, tell your doctor before taking Truvada. Symptoms can be mild to serious and can include: If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. Do not take Truvada to reduce the risk of getting HIV-1 unless you are confirmed to be HIV-negative. Our website services, content, and products are for informational purposes only. It is very important that your doctor check your or your child's progress at regular visits to make sure that this medicine is working properly. But this side effect wasnt reported in studies. Get medical help right away if you have any serious symptoms, including: unexplained weight loss, severe tiredness, muscle aches/weakness that doesn't go away, headaches that are severe or don't go away, joint pain, numbness/tingling of the hands/feet/arms/legs, vision changes, signs of infection (such as fever, chills, swollen lymph nodes, trouble breathing, cough, non-healing skin sores), signs of an overactive thyroid (such as irritability, nervousness, heat intolerance, fast/pounding/irregular heartbeat, bulging eyes, unusual growth in the neck/thyroid known as a goiter), signs of a certain nerve problem known as Guillain-Barre syndrome (such as unsteadiness, loss of coordination, trouble swallowing/speaking/chewing, trouble moving your eyes). To get the most benefit from it, take this product exactly as directed, and follow all prevention actions. Discuss the risks and benefits with your doctor. Truvada may weaken your bones, which could increase your risk of breaking a bone. You should only take Truvada for preexposure prophylaxis (PrEP) to help prevent HIV if you test negative for HIV. Before you start treatment with Truvada, tell your doctor and pharmacist which supplements, herbs, and vitamins you take. The content on this site may not apply to non-U.S. audiences as regulatory control, legal requirements, and/or medical practices may vary in other countries. Note that if you take Truvada to treat HIV, youll take it with other HIV drugs. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. US-TVDC-0001 10/22. If you think you were exposed to HIV-1, tell your healthcare provider right away. If your dose is different, do not change it unless your doctor tells you to do so. The following information includes only the average doses of this medicine. Does Truvada 200 Mg-300 Mg Tablet Tenofovir interact with other drugs you are taking? To learn about Descovys side effects, refer to this article. If it gets worse, your doctor may recommend switching to a different HIV drug. If it is near the time of the next dose, skip the missed dose. For example, you should plan to do the following: Its also important to read the Truvada label and other paperwork that may come with the drug. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of emtricitabine and tenofovir combination in the elderly. Specifically, cannabis may raise the level of tenofovir in your system. Taking Truvada for a long time may increase your risk of developing kidney problems or weakened bones. If you test negative for HBV, its also safe to take Truvada. Otherwise, call a poison control center right away. In studies, the more common side effects reported with Truvada used for PrEP were: How long Truvadas side effects last can vary, depending on the side effect and various other factors. Do my other medications or health conditions increase my risk of side effects with Truvada? Missing doses may increase your risk of getting HIV-1 infection. Call your doctor for medical advice about side effects. Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) are a class of drugs that treat HIV by blocking the enzyme that HIV needs to replicate. For example, Tivicay can sometimes cause serious liver problems, while Isentress can sometimes cause serious skin reactions. Truvada may not be the right treatment option if you have certain medical conditions or other factors affecting your health. (To learn whether Truvada interacts with supplements, herbs, or vitamins, see the Truvada and other interactions section below.). There arent any known interactions between Truvada and vaccines. * For details about Truvadas side effects, see this article. Pregnancy. Truvada can worsen kidney problems. Truvada may be used alone or with other medications. Below are several factors to consider. Children weighing less than 17 kgUse and dose must be determined by your doctor. Drug resistance occurs when a drug no longer works to treat a condition. Truvada by itself is not a complete treatment for HIV-1. But it might not fall out of the normal white blood cell. It may harm them. If you have a liver problem, such as liver failure, tell your doctor before starting Truvada treatment. These drugs reduce the amount of virus in the body by blocking the virus from, HIV-negative people can safely live with HIV-positive people. (An active ingredient is what makes a drug work.). Erectile dysfunction (ED) is often a symptom . Your doctor may order blood tests to monitor your liver function while you take this drug. They can determine whether to prescribe Truvada. Could a new blood biomarker help predict Alzheimer's risk? The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Your doctor can help determine whether Truvada is safe for you. (An active ingredient is what makes a drug work.). They may suggest a treatment to manage your symptoms. This can make the HIV infection harder to treat. You should also be tested for hepatitis B before starting treatment with this medicine. But if you have certain serious side effects, such as liver or kidney problems, these may last a long time or even be permanent. It might, but this is rare. Ask them about other medications that might be better options. And, if you already have a liver problem, taking Truvada may worsen it. Keep all medications away from children and pets. They can help you determine if Truvada is a good option for you. (Tenofovir is one of the active drugs in Truvada.) Truvada contains the active drugs emtricitabine and tenofovir disoproxil. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. Interaction explained. Tell your doctor right away if you have any signs of HIV infection (such as sore throat that doesn't go away, tiredness, fever, night sweats, diarrhea, joint/muscle aches, enlarged lymph nodes). Kidney problems. Kidney disease (eg, acute renal failure, Fanconi syndrome), history of or, Liver disease (eg, hepatitis B infection), history of or. But do not stop taking Truvada unless your doctor recommends it. Its not known for sure if Truvada is safe to take during pregnancy. This can help protect your health and the health of your baby. Call your doctor for medical advice about side effects. ED is often a symptom of another health problem or health-related factor. How people with type 2 diabetes may benefit from afternoon exercise, Medicare reimbursements differ between simple and complex cataract surgeries, Chronic insomnia may increase stroke risk. If you have symptoms of lactic acidosis while taking Truvada, call your doctor right away. But this side effect wasnt reported in studies. Do not allow yourself to run out of this medicine. You can ask your healthcare provider or pharmacist for a list of medicines that interact with Truvada. Truvada may not be safe for everyone and comes with several warnings. They can then use this information to adjust your treatment plan if needed. And do not stop taking Truvada unless your doctor recommends it. The. In some situations, this interaction may cause HIV to worsen. If you take Truvada for PrEP, talk with your doctor about the best way to feed your child. If you have questions about certain lab tests that your doctor recommends, talk with your doctor. Your doctor will test you for HIV before you start taking Truvada for PrEP. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Or they may recommend switching from Truvada to a different HIV drug. An interaction occurs when one substance causes another substance to have a different effect than expected. Find everything you need to know about Truvada (Emtricitabine And Tenofovir), including what it is used for, warnings, reviews, side effects, and interactions. If you are taking the didanosine buffered tablets, take both drug products on an empty stomach. The more people that Gilead can switch to Descovy, the better it is for their bottom line. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Truvada has a boxed warning about the risk of resistance to Truvada. For non-prescription products, read the label or package ingredients carefully. If youve had an allergic reaction to Truvada or any of its ingredients, your doctor will likely not prescribe it for you. Avoid sharing needles with anyone. You must be HIV-negative to start Truvada. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Tenofovir can decrease the effectiveness of another medication, atazanavir (by decreasing blood levels). 2005 - 2023 WebMD LLC, an Internet Brands company. Ask your partners with HIV-1 if they are taking anti-HIV-1 medicine and have an undetectable viral load. However, information suggests that Truvada does not increase the risk of congenital anomalies during the first trimester of pregnancy. (These anomalies are commonly known as birth defects.) Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. As with other medications, Truvada can interact with certain other drugs. Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as depression, anxiety), signs of kidney problems (such as change in the amount of urine, pink/bloody urine). Truvada may cause serious side effects, including: The most common side effects of Truvada in people taking Truvada to treat HIV-1 infection include: Common side effects in people who take Truvada to reduce the risk of getting HIV-1 infection include: These are not all the possible side effects of Truvada. This could increase your risk of side effects. But some serious side effects may last a long time. Ask your healthcare professional how you should dispose of any medicine you do not use. Truvada can cause serious side effects, including: For more information about side effects, see the section "What are the possible side effects of Truvada?". This medicine may cause kidney problems. Taking Truvada could cause another allergic reaction. But Tivicay and Isentress also have some different side effects. Truvada and certain antiviral medications can cause kidney problems, such as kidney damage. US residents can call their local poison control center at 1-800-222-1222. Do not take medications that contain the same or similar ingredients as this product. Unknown or positive HIV-1 status (for Pre-exposure prophylaxis)Should not be used in patients with these conditions. This can increase your risk of side effects from Truvada* and the HIV medications. Read the Medication Guide provided by your pharmacist before you start taking this medication and each time you get a refill. Your doctor may order blood tests to check your liver function from time to time while youre taking Truvada. Side effects arent common with Truvada, especially when its used as preexposure prophylaxis (PrEP) to help prevent HIV. Is the ketogenic diet right for autoimmune conditions? As with other medications, Truvada can. This lowers your chance. Human immunodeficiency virus (HIV) is a virus that strikes the immune system, making it difficult for the body to fight infections and diseases. Other important information for people who take Truvada to help reduce their risk of getting HIV-1 infection: Before taking Truvada to reduce your risk of getting HIV-1 infection: While you are taking Truvada to reduce your risk of getting HIV-1: For people taking Truvada to reduce the risk of getting HIV-1 infection: Do not take Truvada to help reduce your risk of getting HIV-1 if: Truvada can only help reduce your risk of getting HIV-1 before you are infected. If you decide to take Truvada during pregnancy, youre encouraged to enroll in the Antiretroviral Pregnancy Registry. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Truvada is a prescription medicine that is used to: treat HIV-1 infection when used with other anti-HIV-1 medicines in adults and children who weigh at least 37 pounds (at least 17 kg). Inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and pregelatinized starch (gluten free). Some people take this herb to boost their immune system. While there arent many known specifics, below is some general information regarding taking Truvada while pregnant or breastfeeding. Your doctor will perform laboratory tests before starting this medication and periodically during treatment (every 3 months) to make sure that you do not have HIV infection. (An active ingredient is what makes a drug work.). To be fair, this is not the price that anyone (not . A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Alcohol doesnt affect the way Truvada works. Your doctor may prescribe other HIV drugs to take along with Truvada, or they may prescribe a different combination of HIV drugs. Truvada (emtricitabine/tenofovir disoproxil) is a brand-name prescription drug used to treat and help prevent HIV. Key takeaways: Truvada and Descovy are both very effective at preventing HIV in people at risk for infection. Most of the drugs side effects are mild and easily managed. These are known as contraindications. If your doctor confirms youve had a serious allergic reaction to Truvada, they may have you switch to a different treatment. Talk to your pharmacist for more details. This medicine is a blue, oblong, film-coated, tablet imprinted with "GSI" and "705". Drug interactions may change how your medications work or increase your risk for serious side effects. Weighing 22 to less than 28 kgOne tablet once a day. If needed, your doctor may prescribe medication to treat HBV. It is possible to pass HIV to your child through your breast milk. The information contained on this site is intended for audiences in the United States only. In some cases, the problems may be severe. Truvada. Severe liver problems. Keep the medicine in the original bottle that you were given at the pharmacy and keep it tightly closed. A person who takes Truvada every day can lower his or her risk of getting HIV from sex by more than 99% percent and from injection drug use by more than 74% percent, according to the U.S. Centers for Disease Control and Prevention. Cannabis (often called marijuana) and cannabis products, such as cannabidiol (CBD), have been specifically reported to interact with Truvada. The presence of other medical problems may affect the use of this medicine. If youre pregnant or planning to become pregnant, talk with your doctor before starting Truvada treatment. Lab and/or medical tests (such as kidney tests, urine glucose/protein, liver tests, viral load, T-cell counts, blood mineral levels, bone density tests, test for hepatitis B virus) should be done before you start taking this medication and while you are taking it. You should also tell them if youre receiving dialysis. This is the most serious warning from the Food and Drug Administration (FDA). You could also have symptoms if your immune system becomes overactive. Medically reviewed by Drugs.com. Liver problems. But if your symptoms feel life threatening, call 911 or your local emergency number. In rare cases, severe liver problems can happen that can lead to death. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Last updated on Mar 22, 2023. Early diagnosis and treatment can help manage the condition and prevent transmission to others. 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