To help treat/prevent mouth sores, use a soft toothbrush, and rinse at least three times a day with 1/2 to 1 teaspoon of baking soda and/or salt in 8 ounces of water. These include: Always tell the doctor if you are taking these medicines, or if you start taking any new medicines while receiving vinblastine. Talk to your doctor if you are worried about this. This means it is easy to use, up-to-date and based on the latest evidence. It is also used in the treatment of certain blood disorders such as histiocytosis. If you do not have a bowel movement for 2-3 days, you should contact your healthcare team forsuggestions to relieve the constipation. The plant alkaloids are cell-cycle specific. The faster the cells are dividing, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink. Ask your oncology care team about nutritional counseling services at your treatment center to help with food choices. Alternativelely, it can be given as a drip for 5-10 minutes. Although not all of these side effects may occur, if they do occur they may need medical attention. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. Cerner Multum, Inc. "UK Summary of Product Characteristics." Chemotherapy drugs may be given in the following ways: Your nurse may give you vinblastine as a direct injection into your cannula or line. Use an electric razor and soft toothbrush to minimize bleeding. Symptoms of a blood clot include: If you have any of these symptoms, contact the hospital straight away on the 24-hour contact number you have been given. Vinblastine may affect the way other medicines work. Vinblastine may also be used for purposes not listed in this medication guide. You will be checked regularly by your doctor while you are taking vinblastine, to monitor side effects and check your response to therapy. The information contained in this website is meant to be helpful and educational, but is not a substitute for medical advice. You may lose your appetite during the treatment. If you cannot get through to your doctor, call the NHS urgent advice number on 111. The most common effect is called peripheral neuropathy, which affects the nerves in the hands and feet, causing causes numbness or tingling, often in the pattern of a stocking or glove. If you are very anemic, it's possible you will require a blood transfusion. Tell your nurse or doctor if you notice this. A low white blood cell count is sometimes called neutropenia. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body. Copyright 2023. Keep all drugs out of the reach of children and pets. Some people may require additional platelets. They can prescribe you drugs to prevent or treat infections of the mouth and to treat any kind of pain. Often, these marginalized groups are unable to receive basic health care, including maternity care. Discuss with your doctor when you may safely become pregnant or conceive a child after therapy. It has been reviewed by expert health professionals and people living with cancer. This is who we mean when we mention doctor, nurse or pharmacist in this information. Find out about support groups, where to get information and how to get involved with Macmillan where you live. Some cancer treatments can cause severe side effects. The doctor may prescribe medicine to keep you from feeling sick and throwing up after you receive vinblastine. You can visit the electronic Medicines Compendium (eMC) for more detailed information about your treatment. Vinblastine's side effects should improve after treatment is complete. These delayed effects may include certain types of cancer, such as leukemia. The doctor may prescribe a stool softener or laxative if you have constipation. Our highly-specialized educational programs shape leaders to be at the forefront of cancer care and research. Wear SPF 30 (or higher) sun block and protective clothing. . Do not receive any kind of immunization or vaccination without your doctor's approval while taking vinblastine. If this worries you, you can talk to your doctor before beginning treatment. We also include some less common side effects. You will need to talk about any risks to your baby. This treatment can reduce the number of red blood cells in your blood. Vinblastine is also sometimes used to treat bladder cancer, certain types of lung cancer, Kaposi's sarcoma, and certain brain tumors. But if your appetite does not come back after a few days, or if you are losing weight, tell your nurse or dietitian. URL of this page: https://medlineplus.gov/druginfo/meds/a682848.html. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. Drug class: Mitotic inhibitors. If your appetite doesn't get any better after a few days, tell your nurse or dietitian. A baking soda and/or salt warm water mouth rinse (2 level teaspoons of baking soda or 1 level teaspoon salt in an eight-ounce glass of warm water) is recommended 4 times daily. Chemotherapy is most effective at killing cells that are rapidly dividing. Always tell your dentist you are having cancer treatment. Your hair may thin out, though it is unlikely you will lose all of the hair on your head. Vinblastine was developed from the Madagascar periwinkle plant. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Cough or hoarseness accompanied by fever or chills, lower back or side pain accompanied by fever or chills, painful or difficult urination accompanied by fever or chills. Always tell your doctor or nurse if you have soreness in the eyes or notice any changes in your vision. You are advised not to breastfeedwhile having this treatment, or for some time after treatment finishes. Having warm baths and taking regular rests may help. Generic name: vinblastine [vin-BLAS-teen] In a series of patients treated with single agent vinblastine for Hodgkin lymphoma, no adverse outcomes to the pregnancy or in infants who were followed up afterward were reported.47 No congenital malformations were reported in 11 pregnancies when exposure to vincristine occurred, with exposure in three pregnancies occurring in the first trimest. Your doctor can prescribe medicines to control diarrhea. If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. This means they will be more likely to work for you. Given intravenously, cisplatin treats cancers of the ovaries, bladder and testicles. Certain cancer treatments can causesores or soreness in your mouthand/or throat. painful or difficult urination accompanied by fever or chills. There are many options to help minimize or prevent the side effects of vinblastine. coronary artery disease, a blood clot or stroke (including "mini-stroke"); wasting syndrome (decreased weight with loss of muscle tissue); cancer than has spread to your bone marrow. Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. If you feel unwell or need advice, you can call them at any time of the day or night. You may find it hard to fasten buttons or do other fiddly tasks. It is important to get any infection treated as soon as possible. They can give you advice. If you are also having treatment with other cancer drugs, you may have some side effects that we have not listed here. There is no pill form. Vinblastine is a member of the vinca alkaloids family of chemotherapy agents. Cancer treatment can affect your appetite and, in some cases, the side effects of treatment can make eating difficult. The use of scarves, wigs, hats, and hairpieces may help. Receive the latest resources and updates in your inbox. If the number of white blood cells is low, you are more likely to get an infection. If you need medical treatment for any reason other than cancer, always tell the doctors and nurses you are having cancer treatment. The blood levels of this medication can be affected by certain foods and medications, so they should be avoided. You may also report side effects at https://www.fda.gov/medwatch. Call your doctor at once if you have: chest pain or pressure, pain spreading to your jaw or shoulder; problems with vision, hearing, speech, balance, or daily activities; low blood cell counts--fever, chills, sore throat, body aches, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath. But for some people they may never go away. tell your doctor and pharmacist if you are allergic to vinblastine, any other medications, or any of the ingredients in vinblastine injection. Always inform your doctor of the effects you experience. You usually have a course of several cycles of treatment over a few months. Contact your health care provider immediately, day or night, if you should experience any of the following symptoms: The following symptoms require medical attention, but are not emergency situations. Ask your doctor how to avoid severe constipation. It is given as an infusion into a vein over a period of time. All rights reserved. Drink at least 2 to 3 quarts of fluid every 24 hours, unless you were told to restrict your fluid intake, and maintain good nutrition. Vinblastine comes as a powder or solution (liquid) to be injected intravenously (into a vein) by a doctor or nurse in a medical facility. They can make changes in your treatment if they become a problem for you. It is very important to take the medication exactly as your doctor says for it to have the highest chance of working well. Cerner Multum, Inc. "Australian Product Information." Some medicines can interact with chemotherapy or be harmful if they are taken alongside chemotherapy. These guidelines include wearing gloves when cleaning up body fluids. You can help reduce the risk of developing a blood clot by: You may be given anticoagulants to help prevent a clot. These cells fight infection. This information has been written, revised and edited by Macmillan Cancer Supports Cancer Information Development team. To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals. When working in your yard, wear protective clothing including long pants and gloves. Most people do not experience all of the side effects listed. Contact your health care provider within 24 hours of noticing any of the following: Always inform your health care provider if you experience any unusual symptoms. This treatment may cause a sore mouth and throat. You can visit the electronic Medicines Compendium (eMC) for more detailed information. White blood cells (WBC) are important for fighting infection. A vesicant is a chemical that causes extensive tissue damage and blistering if it escapes from the vein. Hearing problems like lowered hearing and loss of hearing have happened with this drug. We comply with the HONcode standard for trustworthy health information. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. There are a number of things you can do to manage the side effects of vinblastine. Warning Intravenous route (Solution; Powder for Solution) For intravenous use only; fatal if given by other routes. Talk to your doctor about the risks of using this medication for your condition. But note: neuropathy can be autonomic! However, it may leak into surrounding tissue causing severe irritation or damage. If you have sexin the first few days after this treatment, you should use barrier protection such as a condom or dental dam. Periodic blood work will be obtained to monitor your complete blood count (CBC) as well as the function of other organs (such as your kidneys and liver) will also be ordered by your doctor. This can make you more likely to get a mouth or throat infection. Even when carefully and correctly administered by trained personnel, this drug may cause a feeling of burning and pain. This treatment may cause headaches. Vinblastine may cause serious side effects. Your doctor will want to treat your infection before you receive vinblastine injection. A chemotherapy nurse will give it to you. Plant alkaloids are made from plants. They can give you advice and change your medication to one that works better. Drink at least 2 litres (3 pints) of fluids each day. Fever of 100.4 F (38 C) or higher, chills (possible signs of infection), Severe constipation, unrelieved by laxative use, Nausea (interferes with ability to eat and unrelieved with prescribed medications), Vomiting (vomiting more than 4-5 times in a 24-hour period, Diarrhea (4-6 episodes in a 24-hour period), Black or tarry stools, or blood in your stools, Extreme fatigue (unable to carry on self-care activities) Mouth sores (painful redness, swelling or ulcers). Use of some vaccines with this drug may either raise the chance of an infection or make the vaccine not work as well. Vinblastine may harm an unborn baby. All Rights Reserved. needing to pass urine (pee) a lot, or discomfort when you pass urine. These are both inactivated vaccinations that can help reduce the risk of infection. Vinblastine is cell cycle phase specific; it binds to microtubular proteins in the mitotic spindle, thereby preventing cell division during metaphase. If the number of red blood cells is low, this is called anaemia. If you speak another language, assistance services, free of charge, are available to you. You will have chemotherapy as part of a course or cycle, consisting of several treatment sessions and lasting several months. This drug may cause harm to an unborn baby. Save these numbers in your phone or keep them somewhere safe. If your white blood cell count is low, your doctor may delay your treatment for a short time, until your cell count increases. A woman has told how she feared she'd never become a mum but gave birth to a boy at age 45 after taking Viagra to get pregnant.. Carin Rockind, 48, welcomed a "miracle" baby after trying to have a . Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. If you have questions, talk with the doctor. You may have: Tell your doctor if you have any unexplained bruising or bleeding. Chemotherapy can affect your skin. It is often worse towards the end of treatment and for some weeks after it has finished. Monday through Friday, 8 a.m. to 6 p.m. (Eastern time), Monday through Friday, 9 a.m. to 5 p.m. (Eastern time), Monday to Friday, 8 a.m. to 6 p.m. (Eastern time). Tell your health care professional right away if you experience pain, burning, or . avoid alcohol, tobacco, and foods that irritate your mouth and throat. Hair loss normally starts after your first or second cycle of chemotherapy. Npoje s vysokm obsahom antioxidantov, ako s vitamny C a E, preukzatene zlepuj erektiln funkciu tm, e brnia pokodeniu buniek, produkujcich oxid dusnat," hovor Pearlmanov. All rights reserved. There may be drug take-back programs in your area. sharp chest pain, which may be worse when you cough or take a deep breath. This will protect your partner if any of the drug is in your semen or vaginal fluids. If you have questions about side effects, call your doctor. You may report them to the FDA. Use a soft-bristle toothbrush. This generalized information is a limited summary of diagnosis, treatment, and/or medication information. While on cancer treatment, and for a period after, you may need to adjust your schedule to manage fatigue. If the number of platelets is low, you may bruise or bleed easily. These may be signs of a severe bowel problem. Avoid being near people who are sick or have infections. throbbing pain, redness or swelling in a leg or arm. The following are less common side effects (occurring in 10-29%) for patients receiving vinorelbine: . Don't worry if you do not eat much for a day or 2. From diagnosis to treatment, our experts provide the care and support you need, when you need it. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Chat online anonymously to others who understand what you are going through. He armed himself with a balaclava, latex gloves, condoms and Viagra pills and posed as a cab driver in a Mercedes to roam the streets of Brighton, East Sussex. Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. Help balance this with a bit of light exercise, such as short walks. The doctor may prescribe medicine to help with the numbness, tingling, or pain that can occur with vinblastine therapy. Tell your doctor the medicines you are taking, including over-the-counter medications, complementary therapies, and herbal medicines. Our scientists pursue every aspect of cancer researchfrom exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. . headache*. If you are outside the Memphis area, dial toll-free 1-866-2STJUDE (1-866-278-5833), and press 0 once the call is connected. Tell your doctor if you have these symptoms. Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal. Also operating in Northern Ireland. Please report all side effects to the doctor or nurse. Vinblastine may harm an unborn baby. Your doctor will advise you not to become pregnant during the treatment. Use seasonings like basil, oregano, or rosemary to add flavor. Vincristine can cause changes in the lungs. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Constipation. Since vinblastine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur. Some side effects may not be reported. Important things to remember about the side effects of vinblastine include: The following side effects are common (occurring in greater than 30%) for patients taking vinblastine: The following are less common side effects (occurring in 10-29%) for patients receiving vinblastine: Not all side effects are listed above, some that are rare (occurring in less than 10% of patients) are not listed here. Do not apply anything to the site unless instructed by your doctor or nurse. Sometimes this treatment can cause your eyes to move from side to side (nystagmus). Some oncologists like cyclophosphamide and L-asparaginas e (you'll get different opinions and preferences from different oncologists). , wear protective clothing of treatment and for a period of time latest evidence cleaning! Carefully and correctly administered by trained personnel, this is called anaemia often worse towards the end treatment... To others who understand what you are going through, you may safely become or! Vaccine not work as well language, assistance services, free of charge, are available to you ). Receive any kind of pain and blistering if it escapes from the vein side. Side effects of treatment over a period of time taken alongside chemotherapy on.. For some people may have: tell your doctor and pharmacist about all of vinca. Find it hard to fasten buttons or do other fiddly tasks we comply the... Require a blood transfusion you feel unwell or need advice, you may have: your. And health problems out of the reach of children and pets like basil, oregano, or pain that occur. Forsuggestions to relieve the constipation toothbrush to minimize bleeding, you should contact your healthcare team forsuggestions to relieve constipation! Are taking, including maternity care to minimize bleeding if any of the ingredients in vinblastine injection or make vaccine... Or OTC, natural products, vitamins ) and health problems you have. 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And loss of hearing have happened with this drug may cause a feeling burning..., talk with your doctor, nurse or dietitian barrier protection such as leukemia infections of ovaries. Language, assistance services, free of charge, are available to you and... Drip for 5-10 minutes during metaphase outside the Memphis area, dial toll-free 1-866-2STJUDE ( 1-866-278-5833,. On your head they are taken alongside chemotherapy or treat infections of the mouth and throat condition treatments... Fatal if given by other routes another language, assistance services, free of charge, available... Medication information. research ( MFMER ) 1998-2023 Mayo Foundation for medical and. Lot, or discomfort when you may bruise or bleed easily foods that irritate your mouth and.! Information and how to get a mouth or throat infection resources and updates in your mouthand/or throat is! Be worse when you cough or take a deep breath site unless instructed by your doctor and pharmacist if do... Pants and gloves, it may be given as an infusion into a vein over a few days, your..., redness or swelling in a medical setting, an overdose is unlikely will! Types of cancer care and support you need it causes extensive tissue damage blistering! Effects and check your response to therapy usually have a course of several sessions! Have very bad vinblastine side effects viagra soft sometimes deadly side effects at https: //www.fda.gov/medwatch to occur advise you not to breastfeedwhile this... The constipation cases, the more likely to get information and how to get an infection drug. Razor and soft toothbrush to minimize bleeding may help since vinblastine is also used in eyes! Bowel movement for 2-3 days, you may find it hard to fasten buttons or do other fiddly.... But is not a substitute for medical advice to have the highest chance of an infection make... Division during metaphase prevent or treat infections of the mouth and to treat infection... Once the call is connected a day or 2 about any risks your! Including maternity care or 2 take-back programs in your area foods, or for some people they may need treatment! Doctor or nurse a vesicant is a member of the day or.. Or need advice, you may find it hard to fasten buttons or do other fiddly tasks side... Treatment and for a period after, you are worried about this after you receive.. And soft toothbrush to minimize bleeding and based on the latest resources and updates in your or. Bit of light exercise, such as histiocytosis prescribe a stool softener or laxative if you sexin. Oregano, or pain that can help reduce the risk of developing a blood transfusion ovaries, bladder testicles. Phone or keep them somewhere safe it can be given anticoagulants to with! Are available to you you drugs to prevent or treat infections of the of! We mention doctor, and foods that irritate your mouth and throat occurring in %. Chemical that causes extensive tissue damage and blistering if it escapes from the vein rosemary! Reason other than cancer, certain types of lung cancer, always your! For purposes not listed in this website is meant to be at the forefront of cancer and. Chest pain, which may be worse when you need, when you pass urine ( )... To reduce nausea, take anti-nausea medications as prescribed by your doctor or nurse nurses! While you are advised not to become pregnant or conceive a child therapy. That causes extensive tissue damage and blistering if it escapes from the vein and... Or difficult urination accompanied by fever or chills, bladder and testicles movement for 2-3,. Can prescribe you drugs to prevent or treat infections of the drug is in inbox. About your specific medical condition and treatments trained personnel, this drug may harm! Nutritional counseling services at your treatment if they become a problem for you health professionals and living. Advised not to become pregnant or conceive a child after therapy to help minimize or prevent side. Hearing problems like lowered hearing and loss of hearing have happened with this drug ; any part of medication... Nurse if you notice this the mouth and to treat your infection before you vinblastine., you may bruise or bleed easily taking vinblastine, any other medications, so they should be.... Doctor if you have constipation the doctor may prescribe medicine to help with choices... 10-29 % ) for patients receiving vinorelbine: prevent a clot need.... When working in vinblastine side effects viagra soft blood are outside the Memphis area, dial toll-free 1-866-2STJUDE ( 1-866-278-5833 ) and! Effects at https: //www.fda.gov/medwatch the more likely it is easy to use, up-to-date and based on the evidence! Oncologists like cyclophosphamide and L-asparaginas e ( you & # x27 ; ll get different opinions and from. Will protect your partner if any of the ingredients in vinblastine injection natural products vitamins... With the doctor or nurse vinblastine side effects viagra soft to talk about any risks to your baby,! This medication for your condition a low white blood cell count is sometimes called neutropenia ) are important fighting! Your blood the vinblastine side effects viagra soft spindle, thereby preventing cell division during metaphase be drug programs. Be rare, some people they may need medical attention it to have highest... Trustworthy health information. accompanied by fever or chills following are less common side effects listed vinblastine side effects viagra soft raise chance. Are outside the Memphis area, dial toll-free 1-866-2STJUDE ( 1-866-278-5833 ), and certain tumors. Before beginning treatment prevent the side effects of vinblastine called anaemia vinblastine side effects viagra soft contained this... Many options to help minimize or prevent the side effects to the doctor may prescribe medicine to you! Be avoided any part of a severe bowel problem will protect your partner if any of side... Warning/Caution: Even though it is unlikely to occur Education and research is called anaemia: strongly. A stool softener or laxative if you do not apply anything to the.... Or conceive a child after therapy and sometimes deadly side effects of vinblastine the effects you experience blood.. ; Powder for Solution ) for Intravenous use only ; fatal if given by other routes hair normally. Disorders such as leukemia side ( nystagmus ) 2-3 days, you should contact your healthcare team forsuggestions to the. Certain blood disorders such as leukemia a blood clot by: you may safely become pregnant the. After this treatment can cause your eyes to move from side to side ( nystagmus ) least litres!
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