If you need to stop taking either form of Wellbutrin for any reason, talk with your doctor first. The bright light may affect brain chemicals that improve mood and sleep, and ease SAD symptoms. Serious side effects and their symptoms can include: * For more information about this side effect, see Side effect details below. Not everyone taking these drugs will experience a change in weight. Its important that you do not take more Wellbutrin than your doctor advises. The active drug in the tablets is bupropion hydrochloride, which belongs to the aminoketone class. 63% of reviewers reported a positive effect, while 18% reported a negative effect. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. Investigating the power of music for dementia. The following information describes dosages that are commonly used or recommended. Generic Wellbutrin XL at certain pharmacies is less than $3 with a free GoodRx discount. Available for Android and iOS devices. If you dont feel like your depression symptoms are easing, talk with your doctor. Do not use more of these medications than your doctor prescribes. The websites also offer tools to help you find low-cost healthcare, as well as educational resources. Some people have reported these reactions while taking the medications. * Examples of these drugs include: Bupropion hydrochloride increases the activity of dopamine (a type of brain chemical). * The SR and XL forms of bupropion hydrochloride ER oral tablets have a boxed warning for suicidal thoughts and actions. SAD also has non-drug treatment options, such as talk therapy or light therapy. See also: Wellbutrin SR side effects in more detail. No matter your age, your doctor will monitor you for symptoms of suicidal thoughts and actions during your treatment with either medication. ER oral tablets include two forms of the drug. If youre interested in using Wellbutrin SR or Wellbutrin XL instead of their generic forms, talk with your doctor. Medicine Assistance Tool and NeedyMeds are two websites offering resources that may help decrease the price you pay for either medication. Conclusions: Side Effects Warning and Interactions What is the most important information I should know about Wellbutrin for ADHD? This is also normal. Zoloft and Wellbutrin both have side effects. These may include: Typically, your doctor will start you on a low dosage. No, neither form of Wellbutrin is approved for weight loss or anxiety at this time. Before taking either medication, talk with your doctor and pharmacist. Strange thoughts or actions. Save with patient assistance programs. They both contain the active ingredient bupropion. This is because symptoms of SAD generally occur during the winter and get better in spring. This can include setting an alarm or putting a note where youll see it, such as on your bathroom mirror or bedside table. For more information see Suicidal actions and thoughts in the Bupropion hydrochloride ER oral tablets side effects section above. Disclaimer. It also helps keep the drug from harming the environment. Wellbutrin SR and XL can also raise the risk of seizures in some people, especially those who have had an eating disorder like anorexia or bulimia. Typically, naltrexone hydrochloride is used to treat overdoses of drugs called opioids. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. Keep in mind that decreased appetite is a common side effect of the SR form of bupropion hydrochloride ER oral tablets. As with all medications, the cost of the SR and XL forms of bupropion hydrochloride ER oral tablets can vary. Using this service may help lower the drugs cost and allow you to get your medication without leaving home. Health Technol Assess. Its unknown how often allergic reactions occurred in people using these medications. Wellbutrin contains the active drug bupropion. These other drugs include: You should not take bupropion hydrochloride and MOAI drugs within 14 days of each other. It is also used as part of a support program to help people stop smoking. Cancer patients (N = 648) were prescribed bupropion XL (n = 454) or SR (n = 194) alone or in combination with nicotine replacement therapy (NRT) for treating smoking from September 2006 to December 2017. To learn more, talk with your doctor. In three clinical studies, the XL form of bupropion hydrochloride ER oral tablets was effective for preventing episodes of depression in adults with SAD. Youll likely take the drug from autumn to early spring and stop taking it during the summer. The starting dosage is the first dosage your doctor will typically prescribe. Generic Wellbutrin SR at certain pharmacies is less than $4 with a free GoodRx discount. Seizures may occur with use of either form of bupropion hydrochloride ER oral tablets (SR or XL). Do not stop taking Wellbutrin SR or XL on your own. Doing so could increase your risk for seizures. (Bupropion hydrochloride is a type of antidepressant drug. Its important to note that mental health may be at risk when depression isnt treated during pregnancy. Your doctor or pharmacist will typically recommend taking your doses of Wellbutrin SR at least 8 hours apart. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The maintenance dosage is the dosage you take on a regular basis to keep a steady level of the drug in your body. Bookshelf MDD is a common type of depression. The SR and XL forms of bupropion hydrochloride ER oral tablets have a boxed warning for suicidal thoughts and actions. In some cases, you may need emergency treatment with linezolid or intravenous (IV) methylene blue. XL demonstrated noninferiority in treatment efficacy compared to SR when excluding those on combined treatment with NRT. Keep in mind that outcomes in animals dont always predict effects in humans. While using any form of bupropion hydrochloride for treating depression, you should not suddenly stop taking the medication. Note: Some of the drugs listed here are used off-label to treat these specific conditions. doi: 10.1002/14651858.CD009329.pub2. Because SAD is a form of MDD, the same antidepressants may be used to treat both conditions. Can diet help improve depression symptoms? Is the ketogenic diet right for autoimmune conditions? But weight loss isnt considered a common side effect of these medications. The dose is the same for both major depressive disorder and SAD. and transmitted securely. Most people with SAD have depression symptoms every year. Note: This article describes typical dosages for Wellbutrin provided by the drugs manufacturer. Note: The active drug, bupropion hydrochloride also comes as an immediate-release tablet. Keep reading for specific information about the dosage of Wellbutrin, including its strengths and how to take medication. You can also talk with your doctor or pharmacist. The SR form of bupropion hydrochloride ER oral tablets comes in three strengths: 100 milligrams (mg), 150 mg, and 200 mg. The starting dosage is the first dosage your doctor will typically prescribe. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Do not stop taking Wellbutrin XL without first talking with your doctor. PMC If you have a history of seizures or eating disorders, let your healthcare provider know. However, be sure to take the dosage your doctor prescribes for you. But more information is needed to confirm whether these medications are safe to use while pregnant. This is called withdrawal. ChildrenUse and dose must be determined by your doctor. Randomized trial of nicotine replacement therapy (NRT), bupropion and NRT plus bupropion for smoking cessation: effectiveness in clinical practice. Both XL and SR formulations are approved to treat major depressive disorder. Is the ketogenic diet right for autoimmune conditions? This can include setting an alarm or timer on your phone or downloading a reminder app. But doctors may prescribe it off-label for this use. Does Wellbutrin XL/SR cause weight gain or loss? MDD and SAD are types of depression. However, because Wellbutrin XL is an extended-release medication, if you miss a dose, do not take it when you remember. This is the dose you should stay on. If you need to stop taking Wellbutrin, talk with your doctor first. Bupropion hydrochloride ER oral tablets are generic prescription medications. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021515s036lbl.pdf, https://gskpro.com/content/dam/global/hcpportal/en_US/Prescribing_Information/Wellbutrin_SR/pdf/WELLBUTRIN-SR-PI-MG.PDF, https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2002.86. Your doctor may adjust your dose as needed. Some results showed harm to animals offspring, but other results didnt. Wellbutrin XL is also approved to treat seasonal affective disorder. 8600 Rockville Pike lack of interest in activities or relationships, serotonin-2 antagonist reuptake inhibitors (SARIs), such as trazodone, tricyclic antidepressants (TCAs), such as, antiplatelet drugs (medications used to prevent, antipsychotics (medications used to treat, antiarrhythmics class 1C (medications used to treat fast, skipped, or uneven heartbeats), such as propafenone (Rythmol SR) and flecainide, other forms of bupropion, such as bupropion hydrobromide (, intravenous methylene blue (ProvayBlue), which is a blood disorder drug. * Doctors may prescribe the SR form off-label for SAD. But if they become more severe or dont go away, talk with your doctor or pharmacist. Once youre taking a maintenance dose of the SR or XL form of bupropion hydrochloride ER oral tablets, it may take several weeks until your MDD or SAD symptoms ease. We comply with the HONcode standard for trustworthy health information. Another difference is that Wellbutrin SR is only used for major depressive disorder (MDD), whereas Wellbutrin XL can be used for both MDD and seasonal affective disorder (SAD). GoodRx can help make your prescription more affordable. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Youll typically take the XL form once per day in the morning. Published on July 6, 2022 Key takeaways: Celexa (citalopram) and Wellbutrin (bupropion) are FDA-approved to treat depression in adults. If recommended by your doctor, you may be able to receive a 90-day supply of either medication, so theres less concern about running out of the medication. For this reason, there arent any recommended Wellbutrin dosages to treat weight loss or anxiety. What are bupropion hydrochloride ER oral tablets? However, this is an off-label use of the drug. The SR and XL forms of bupropion hydrochloride ER oral tablets are effective for treating MDD. Breakthrough depression means when depressive episodes keep occuring despite adequate antidepressant medication. To learn more about how generics compare with brand-name drugs, see this article. Accessibility Thomas KH, Dalili MN, Lpez-Lpez JA, Keeney E, Phillippo D, Munaf MR, Stevenson M, Caldwell DM, Welton NJ. Its unknown whether the SR and XL forms of bupropion hydrochloride ER oral tablets are safe to take during pregnancy.*. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Smoking cessation medicines and e-cigarettes: a systematic review, network meta-analysis and cost-effectiveness analysis. This may cause side effects.*. If youre trying to quit smoking and are interested in using the SR form of bupropion hydrochloride ER oral tablets, talk with your doctor. In this first published direct comparison of their effectiveness and adverse event profiles, we found that bupropion XL is likely therapeutically equivalent to bupropion SR when treating smoking among cancer patients, and produces similar side effects. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. However, the reactions didnt occur during clinical studies. This date is typically 1 year from the date they dispensed the medication. Budeprion SR; Budeprion XL; Buproban; Forfivo XL; Wellbutrin; Wellbutrin SR; Wellbutrin XL; Zyban; Descriptions. And they have the same active drug: bupropion. These may not be the safest medications for you. But its not known how this affects females who took the drug or children who are breastfed. In the same studies, a small percentage of people gained more than 5 pounds: 3% taking 300 mg and 2% taking 400 mg. Bupropion may also be used to help people stop smoking. The 988 Suicide and Crisis Lifeline is available 24 hours a day at 988. Its unclear how often seizures occur with these medications. To view a report comparing 3 (or more) medications, please sign in or create an account. If you miss a dose of Wellbutrin SR, you should take it as soon as you remember and then continue with your usual dose schedule. This way, youll take the drug only to help prevent episodes of depression in SAD during winter. A boxed warning is the most serious warning from the FDA. Unable to load your collection due to an error, Unable to load your delegates due to an error. This limits the risk of withdrawal. Ankylosing Spondylitis Pain: Fact or Fiction, https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/020358s066lbl.pdf, https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/021515s044lbl.pdf, How people with type 2 diabetes may benefit from afternoon exercise, Medicare reimbursements differ between simple and complex cataract surgeries, Chronic insomnia may increase stroke risk. With SAD, people typically start to have depression symptoms in late fall or early winter when theres less sunlight. No foods have been specifically reported to interact with bupropion hydrochloride. Call your doctor right away if you have serious side effects. The daily dose is usually taken in the morning. Federal government websites often end in .gov or .mil. Bupropion hydrochloride ER oral tablets are a type of antidepressant medication called a norepinephrine and dopamine reuptake inhibitor (NDRI). Learn more about the types of depression, what it feels like, how to seek help, and more. A boxed warning alerts doctors and patients about drug effects that may be dangerous. The XL form of bupropion hydrochloride ER oral tablets is FDA-approved to prevent episodes of depression in adults with seasonal affective disorder (SAD). This is the typical recommended dosage of Wellbutrin XL for people with depression. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Fortunately, one antidepressant rarely causes sexual side effects, Wellbutrin (bupropion). This medication comes in sustained-release or extended-release oral tablets. The difference between Wellbutrin XL and Wellbutrin SR is how quickly they are released and then absorbed into the body. Bupropion, the active ingredient in this medicine, is an antidepressant medication that works by changing the levels of chemicals in the brain. During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 then 988. Stopping Wellbutrin suddenly may increase the risk of certain side effects, including seizure. The maximum dosage of Wellbutrin SR is 400 mg per day. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. * The SR form of bupropion hydrochloride ER oral tablets has a boxed warning for suicidal thoughts and actions. View all Its possible. This is the most serious warning from the FDA. Wellbutrin XL is usually continued until winter is over or until SAD symptoms wear off. You can take Wellbutrin SR with or without food. Drug misuse refers to using a drug in a different way than how the doctor prescribed it. If you currently take 150 mg of Wellbutrin XL, your doctor may increase your dose to 300 mg. Generics are considered to be as safe and effective as their parent brand-name medication. Differences between Wellbutrin XL and Wellbutrin SR The difference between Wellbutrin XL and Wellbutrin SR is how quickly they are released and then absorbed into the body. Comparing Wellbutrin SR vs Wellbutrin XL Wellbutrin SR (bupropion) Wellbutrin XL (bupropion) Prescription only Prescribed for Major Depressive Disorder, Depression. Theyll gradually increase it as needed. Typically, youll take this once per day when you first wake up. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. A dependence can develop even if you take a drug exactly as prescribed. These medications are approved for treating only major depressive disorder and seasonal affective disorder in adults. The following lists contain some of the key side effects that may occur while taking either of these medications. Wellbutrin XL, Wellbutrin SR, and Wellbutrin generics come in different forms and strengths. Wellbutrin SR is FDA-approved to treat depression and to help people quit smoking. Both Wellbutrin SR and XL come in affordable generic versions. Because XL versions release medication slower in your body than SR versions, you usually take Wellbutrin XL or bupropion XL once a day in the morning. official website and that any information you provide is encrypted Your doctor will ultimately prescribe the smallest dosage that provides the desired effect. If you have insurance, youll also need to check whether your plan will cover the brand names. They can recommend the best way to slowly decrease your dose of Wellbutrin to prevent side effects from occurring. Note: Both the SR and XL forms of bupropion hydrochloride ER oral tablets may smell strange. SSD occurs when a person experiences symptoms of depression that do not meet the criteria for diagnosis of another type of depression. This article addresses only the SR and XL forms of bupropion hydrochloride ER tablets. Please seek medical advice before starting, changing or terminating any medical treatment. In a naturalistic open-label study, we compared the effectiveness and the adverse event profiles of XL and SR in treating cancer patients for smoking. Off-label drug use means using a drug for a purpose other than what its been approved for by the FDA. Wellbutrin XL is designed to slowly release medication over a 24-hour period, meaning you should only need to take it once a day. Wellbutrin SR is approved to treat depression and help people quit smoking. Some Medicare plans may help cover the cost of mail-order medications. Both of these medications release slowly into your body over time. * ER stands for extended release, and this means that the drug is released slowly in the body. With light therapy, you sit by a box that mimics natural sunlight. Certain drugs may affect how your body processes bupropion hydrochloride. However, your doctor will monitor your condition and medication use. GoodRx works to make its website accessible to all, including those with disabilities. Be sure to tell your doctor about any kidney or liver problems that you have before starting treatment with Wellbutrin. If you no longer need to take your medication and have leftover drug, its important to dispose of it safely. Wellbutrin (bupropion) is one of the most popular medications prescribed to treat depression. For the XL form of bupropion hydrochloride ER oral tablets, youll likely take it once per day, usually in the morning. Wellbutrin SR may also be used for purposes not listed in this medication guide. Use their preferred relay service or dial 711 then 988 create an account youre having a medical emergency have about... Of depression in SAD during winter day, usually in the morning should. Release medication over a 24-hour period, meaning you should not take bupropion ER. 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