If you choose to take olanzapine (Zyprexa) during pregnancy, you're recommended to enroll in the National Pregnancy Registry for Atypical Antipsychotics by visiting their website or by calling 1-866-961-2388. If you experience a fall while taking olanzapine (Zyprexa), contact your provider. Detailed Zyprexa Intramuscular dosage information. Are you looking for information on Zyprexa Relprevv (olanzapine) long-acting injection advice about side effects. Identify the mechanism of action of olanzapine. Olanzapine belongs to the class of medicines known as atypical antipsychotics. Symbyax is dosed between 3 mg/25 mg (olanzapine/fluoxetine) per day and 12 mg/50 mg (olanzapine/fluoxetine) per day. However, it is often covered by insurance and generic forms are also available. over counter substitutes viagra. Cyclobenzaprine relaxes muscles by reducing muscle hyperactivity via gamma and alpha motor systems (these are nerve fibers that directly connect with skeletal muscle and are responsible for muscle contraction). Typically, there isn't a set amount of time that you need to take this medication. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.AmprenavirBetel NutCiprofloxacinFluvoxamineFosamprenavirHaloperidolRitonavirValproic Acid. Gelatin contains the amino acid glycine, which is considered an inhibitory neurotransmitter. Keep in mind that sometimes it can take a while to find the right antipsychotic that works for you. For example, olanzapine (Zyprexa) can change your blood pressure, so you might need to adjust the dose of blood pressure medications if you're taking any. You can click on the numbers in the parentheses (1, 2, etc.) Last updated on Nov 11, 2022. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. Other side effects not listed may also occur in some patients. If you are 65 or older, use Zyprexa Intramuscular (olanzapine injection) with care. Generic name: Olanzapine Olanzapine (Zyprexa) can raise cholesterol (fat) levels in your blood and can cause weight gain. When you pick up your medications at the pharmacy you may notice that they are typically dispensed in amber colored vials or plastic containers. The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C. Some estimates allege that approximately one in ten Americans suffer from some level of depression and/or anxiety. These are neurotransmitters that are directly connected to the mood and behavior of the user among other things. Maintenance Treatment The efficacy of ZYPREXA for the maintenance treatment of bipolar I disorder in the adolescent population has not been evaluated; however, maintenance efficacy can be extrapolated from adult data along with comparisons of olanzapine pharmacokinetic parameters in adult and adolescent patients. Your provider will adjust your dose based on how well it's working to treat your condition and if you're having side effects. Is Zyprexa short-acting? Below you'll find some of the most effective natural nervousness relief supplements on the market today, in our opinion. After opening sachet, peel back foil on blister. 2.5mg Even if the medication is working, you may experience some unwanted side effects. Along with its needed effects, a medicine may cause some unwanted effects. The recommended dose in these patients is 10 mg. A lower dose of 5 or 7.5 mg may be considered when clinical factors warrant [see Clinical Studies (14.3)]. Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. If you experience any of these symptoms while taking olanzapine (Zyprexa), get medication attention as soon as possible. Zyprexa (olanzapine) is anatypical antipsychotic medication used in the treatment of bipolar disorder, schizophrenia, and treatment-resistant depression. Don't try to push the tablet through the foil; this can damage the medication. Tell all of your health care providers that you take Zyprexa Intramuscular (olanzapine injection). Table 1 above demonstrates the appropriate individual component doses of ZYPREXA and fluoxetine versus Symbyax. When dosage adjustments are necessary, dose increments/decrements of 5 mg QD are recommended. How does olanzapine (Zyprexa) differ from other atypical antipsychotics? It depends: That would depend to some extent on the condition being treated, the dosing used, and the delivery method (oral vs im). KarXT is a schizophrenia medication in development. However, the efficacy of repeated doses of intramuscular olanzapine for injection in agitated patients has not been systematically evaluated in controlled clinical trials. Antimanic efficacy was demonstrated in a dose range of 5 mg to 20 mg/day in clinical trials [see Clinical Studies (14.2)]. Although Zyprexa has been found to provide benefits in the treatment of schizophrenia, bipolar disorder, and depression, it can also result in unwanted side effects. Zyprexa increases the risk of death due to cerebrovascular events in older adults with dementia-related psychosis. We asked 68 people what they think about olanzapine (Zyprexa): Get Olanzapine (Zyprexa) for as low as $5.00, Olanzapine (Zyprexa) can raise your blood sugar levels. Today, more than 15 years after stopping the Zyprexa, I am generally 15 pounds too heavy. Olanzapine (Zyprexa) can raise your blood sugar levels. Immediately upon opening the blister, using dry hands, remove tablet and place entire ZYPREXA ZYDIS in the mouth. It can also be combined with fluoxetine for treatment-resistant depression or when treating depressive episodes in people with bipolar I disorder. Olanzapine (Zyprexa) can raise your blood sugar and cholesterol levels as well as raise your appetite, all of which can lead to weight gain. Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. Each tablet contains olanzapine equivalent to 2.5 mg (8 mol), 5 mg (16 mol), 7.5 mg (24 mol), 10 mg (32 mol), 15 mg (48 mol), or 20 mg (64 mol). Please read the full product reviews disclaimer. This is because caffeine affects how well olanzapine (Zyprexa) is broken down in your body, which raises your risk for side effects. You may report side effects to the FDA at 1-800-332-1088. Taking it for symptoms related to bipolar disorder - working wonders. Give by deep IM inj. Dr. Mark Reynolds answered. The safety of doses above 20 mg/day has not been evaluated in clinical trials. When dosage adjustments are necessary, dose increments/decrements of 2.5 or 5 mg are recommended. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. If you notice changes in your skin (e.g., rash, blisters, swollen lymph nodes, skin reddening, skin peeling) or experience swelling in your face or trouble breathing, stop using olanzapine (Zyprexa) and get medical attention right away. 2015;21(23):3280-3297. doi:10.2174/1381612821666150619092903. compare prices cialis 20mg. Also taking the rx for say mood stabilization. BADHGG 14 April 2012. When dosage adjustments are necessary, dose increments/decrements of 5 mg QD are recommended. People who have a predisposition to hypotensive reactions should also be started at a lower dose and carefully monitored when increasing the dosage. Can occur with Viagra: mild and temporary . Note: Results may vary about any product effectiveness. Before taking Zyprexa, it's helpful to understand how it's used, the potential side effects, and any precautions you should consider. Read it with care. You may report side effects to the FDA at 1-800-FDA-1088. doi:10.1007/s40268-013-0030-8. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Read all information given to you. It's taken by mouth or dissolved under the tongue once daily. If your problem is an only slight depression, it may be better to take other over-the-counter products like dietary supplements for the problem. Your provider will likely measure your prolactin levels during treatment to make sure they aren't too high. Your provider might suggest olanzapine (Zyprexa) as a possible option to try. Olanzapine (Zyprexa) can cause nausea, weight gain, and dizziness in some people. 2013;13(4):281288. Dose Selection for Agitated Adult Patients with Schizophrenia and Bipolar I Mania The efficacy of intramuscular olanzapine for injection in controlling agitation in these disorders was demonstrated in a dose range of 2.5 mg to 10 mg. We comply with the HONcode standard for trustworthy health information. In general the earliest effect would be in about 3-7 days with further increase in effect over the next 4-6 weeks. Available for Android and iOS devices. Healthcare professionals review articles for medical accuracy. How does cialis work, Cialis experiences forum How to get generic cialis. Answers. Zyprexa should be kept in a closed container out of the reach of children. Tablets and orally disintegrating tablets: The tablets are taken by mouth and swallowed, while the orally disintegrating tablets (ODTs) are placed on the tongue where they dissolve without you needing to swallow. Zyprexa can cause serious side effects, especially when the user is suffering from certain medical conditions or when combined with other medications. Make sure to get up slowly and try to hold onto something for stability. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Dosing in Special Populations The recommended starting dose is 5 mg in patients who are debilitated, who have a predisposition to hypotensive reactions, who otherwise exhibit a combination of factors that may result in slower metabolism of olanzapine (e.g., nonsmoking female patients 65 years of age), or who may be more pharmacodynamically sensitive to olanzapine [see Warnings and Precautions (5.14), Drug Interactions (7), and Clinical Pharmacology (12.3)]. Experts aren't exactly sure how olanzapine works but suggest it has effects on neurotransmitters such as dopamine and serotonin in the brain. In most cases, your physician will start you on a low dose of the medication and assess your response before gradually increasing your dose until optimal effects are achieved. Is olanzapine (Zyprexa) safe to take while pregnant? Outline the importance of collaboration and communication among interprofessional team members to improve outcomes and treatment efficacy for patients who might benefit from therapy with olanzapine. Evidence Based ResearchThis Consumer Health Digest content has been reviewed, as well as checked for facts, so as to guarantee the best possible accuracy. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Olanzapine is a medication for schizophrenia and bipolar disorder that, when taken with other medications, can have severe interactions. Your risk is higher if you're also taking other medications that can cause drowsiness, such as benzodiazepines, anxiety medications, muscle relaxants, and sleep medications. Zyprexa may also impair a persons ability to think or react so you have to be very careful when doing anything that requires you to be alert like operating heavy machinery. ZYPREXA IntraMuscular should not be combined in a syringe with diazepam injection because precipitation occurs when these products are mixed. Physical Incompatibility Information ZYPREXA IntraMuscular should be reconstituted only with Sterile Water for Injection. Typical and atypical antipsychotics are similar. Dosage adjustments, if indicated, should be made with the individual components according to efficacy and tolerability. Why Are Certain Medications Dispensed in Their Original Containers? The following table demonstrates the appropriate individual component doses of ZYPREXA and fluoxetine versus Symbyax. Some of the most common include those related to anxiety disorders, mood disorders, insomnia, and agitation. If ongoing olanzapine therapy is clinically indicated, oral olanzapine may be initiated in a range of 5-20 mg/day as soon as clinically appropriate [see Dosage and Administration (2.1, 2.2)]. taken, how much, and when it happened. Schizophrenia in adults and children age 13 years and older The list below does not include all possible drug interactions with olanzapine (Zyprexa). It takes around a week for Zyprexa to reach a steady state in the body. The dose of the drug may be adjusted to help minimize these effects. But most guidelines recommend that you need to take an antipsychotic for at least 1 to 2 years after a schizophrenic episode. National Pregnancy Registry for Atypical Antipsychotics, Excedrin (acetaminophen / aspirin / caffeine), Drug Reaction with Eosinophilia and Systemic Symptoms. Safety of co-administration of doses above 18 mg olanzapine with 75 mg fluoxetine has not been evaluated in clinical studies. 1. What You Should Know About Oral Zyprexa (Olanzapine). Carton L, Cottencin O, Lapeyre-Mestre M, et al. Talk with the doctor. Zyprexa may also lead to other long-term side effects, including: Zyprexa is available as 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg, and 20 mg tablets. Within six hours, peak blood levels can be reached if you take a single dose of oral olanzapine. ZYPREXA IntraMuscular reconstituted with Sterile Water for Injection should be used immediately (within 1 hour) after reconstitution. Receive price alerts, news, and other messages from GoodRx about olanzapine (Zyprexa) and other healthcare topics and relevant savings offers. Theyre fast, easy-to-use and free! Learn more about Zyprexa (Olanzapine . Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Do not push the tablet through the foil. Uses Before taking Warnings Side effects Overdose Dosage Warning There is a higher chance of death in older adults who take Zyprexa Intramuscular (olanzapine injection) for mental problems caused by dementia. One common and possibly serious side effect of Zyprexa is significant weight gain, which has been reported as one of the top reasons people choose to stop taking the medication. It works by helping to balance the levels of dopamine and serotonin in the brain, which can improve thinking, behavior, and mood. This ensures the highest standard of scientific accuracy. You may start to notice some effects after a couple of weeks, including improvements in symptoms such as disorganized thinking, delusions, and hallucinations. That means it essentially exhibits some of the same Characteristics of anti-anxiety and anti-depressant medsbut without the side effects. How it works Olanzapine may be used to treat schizophrenia or bipolar disorder. J Clin Invest. Dose Selection for Agitated Adult Patients with Schizophrenia and Bipolar I Mania, Intramuscular Dosing in Special Populations, Directions for Preparation of ZYPREXA IntraMuscular with Sterile Water for Injection, Table 1: Approximate Dose Correspondence Between Symbyax. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Taking it increases the risk of dehydration or overheating so you need to drink plenty of fluids when exercising or if the weather is hot. There is a higher chance of death in older adults who take Zyprexa Intramuscular (olanzapine injection) for mental problems caused by dementia. Do not push tablet through foil. This drug should not be on the market. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. How fast does zyprexa (olanzapine) start working? Gelatin, Mannitol, Aspartame, Sodium methyl hydroxybenzoate and Sodium propyl hydroxybenzoate, VitaPost Stress Support | Ashwagandha & Chamomile. If you are planning to harm yourself or the want to harm yourself gets worse. Olanzapine. Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor. BAP guidelines on the management of weight gain, metabolic disturbances and cardiovascular risk associated with psychosis and antipsychotic drug treatment. . Please follow the instructions listed below to upload your electronic proof of purchase. Zyprexa may also increase an individual's cholesterol levels. Hobbs D, Karagianis J, Treuer T, Raskin J. ZYPREXA and fluoxetine in combination have not been systematically studied in patients over 65 years of age or in patients under 10 years of age [see Warnings and Precautions (5.14), Drug Interactions (7), and Clinical Pharmacology (12.3)]. The healthcare provider who elects to use ZYPREXA for extended periods should periodically reevaluate the long-term usefulness of the drug for the individual patient. ZYPREXA (olanzapine) is not approved for the treatment of patients with dementia-related psychosis (see WARNINGS). The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. This can become permanent if it's not caught in time. 8 Olanzapine Interactions You Should Watch Out for, The Benefits of Abilify, Plus What to Know About Side Effects, Uses, and Costs, What to Know About KarXT and Other Medications Being Studied for Schizophrenia, 10 Things to Know About the Symptoms of Bipolar Disorder in Women, 9 Olanzapine Side Effects You Should Know About, Bipolar depression in adults and children age 10 years and older, Depression that haven't responded well to other treatments, Irritability associated with autistic disorder (children). Do not administer intravenously or subcutaneously. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: difficulty having a bowel movement (stool). Signs of an allergic reaction, like rash; Trouble controlling body movements, twitching, change in balance, trouble swallowing or speaking. If agitation warranting additional intramuscular doses persists following the initial dose, subsequent doses up to 10 mg may be given. The information contained in this website is provided for general informational purposes only. This is the reason blood tests need to be performed regularly and physician visits should be regular when taking this drug. In general, antipsychotics can raise the risk of abnormal muscle movements and withdrawal symptoms in babies at birth if taken by mothers during the last 3 months of pregnancy. Let your provider know if you have PKU so they can prescribe a different formulation of olanzapine (Zyprexa) that might be safer for you. Before taking Zyprexa, I was slim and never had a weight problem. U.S. National Library of Medicine. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. 2 doctor answers 2 doctors weighed in Share Dr. Stuart Hickerson answered Family Medicine 34 years experience Kinetics: Zyprexa ( olanzapine) when taken orally peaks at 6 hours after taking. Thank you, {{form.email}}, for signing up. It can also decrease agitation and help the user become more active and participate in normal daily activities. Created for people with ongoing healthcare needs but benefits everyone. Leave a review and share your experience with others. If you are unsure about your timing, call the prescribing physician to be safe. We do not verify or endorse any claims made in these reviews. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Olanzapine versus risperidone in children and adolescents with psychosis: A meta-analysis of randomized controlled trials. The following table provides injection volumes for delivering various doses of intramuscular olanzapine for injection reconstituted with Sterile Water for Injection. At times, I can feel a bit nauseous or shaky but the relief I feel is worth it. There may be drug take-back programs in your area. generic viagra uk europe. All three of these factors combinedweight gain, high blood sugar, and high cholesterolcan increase a person's risk of heart disease. If you have questions about side effects, call your doctor. To ensure that the products meet safety and effectiveness standards, we scrutinize the following: Our rigorous vetting process aims to help you find trusted products for your health and wellness needs. Can Antidepressants and Anti-Anxiety Drugs Cause Erectile Dysfunction? Your provider will likely order blood tests regularly throughout treatment with olanzapine (Zyprexa) to make sure your blood sugar and cholesterol aren't too high. But since olanzapine (Zyprexa) typically causes sleepiness, it's recommended to take in the evening or at night time. But the different medications in this class work differently. All trademarks, registered trademarks and service-marks mentioned on this site are the property of their respective owners. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. Some side effects may occur that usually do not need medical attention. Read more about, NuviaLab Relax | Stress Relief Mood Support. It is also available in 5 mg, 10 mg, 15 mg, and 20 mg orally disintegrating tablets. Drug class: Atypical antipsychotics. This means it might cause different side effects than some of the other antipsychotics. Efficacy in adolescents with schizophrenia was demonstrated based on a flexible dose range of 2.5 to 20 mg/day in clinical trials, with a mean modal dose of 12.5 mg/day (mean dose of 11.1 mg/day). While some people require medication to deal with these occasionally crippling symptoms, others may find an all-natural product helpful. These side effects may go away during treatment as your body adjusts to the medicine. With any medication, there are risks and benefits. You must check Quetiapine rebalances dopamine and serotonin to improve thinking, mood, and behavior. Dosage adjustments, if indicated, can be made according to efficacy and tolerability within dose ranges of oral olanzapine 5 to 12.5 mg and fluoxetine 20 to 50 mg. Antidepressant efficacy was demonstrated with ZYPREXA and fluoxetine in combination in adult patients with a dose range of olanzapine 6 to 12 mg and fluoxetine 25 to 50 mg. Safety of co-administration of doses above 18 mg olanzapine with 75 mg fluoxetine has not been evaluated in clinical studies. The olanzapine (Zyprexa) orally disintegrating tablets (ODTs) contain phenylalanine, a component of the artificial sweetener aspartame. Although rare, olanzapine (Zyprexa) can cause serious skin reactions, such as Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS). If you think there has been an overdose, call your poison control center or get medical care right away. a Symbyax (olanzapine/fluoxetine HCl) is a fixed-dose combination of ZYPREXA and fluoxetine. Check with your This is more likely to happen the longer you take medications like olanzapine (Zyprexa). There is no family history going back 3 generations. This is called dementia-related psychosis. Curr Pharmaceut Des. Dosage form: tablets, orally disintegrating tablets, injection If your symptoms dont improve or worsen, contact your physician for the appropriate action. You could have more side effects. Directions for Preparation of ZYPREXA IntraMuscular with Sterile Water for Injection Dissolve the contents of the vial using 2.1 mL of Sterile Water for Injection to provide a solution containing approximately 5 mg/mL of olanzapine. Substances that may cause interactions when taken with Zyprexa include: Never start or stop Zyprexa without seeking the advice of your healthcare provider. Cialis Jelly 20 mg x 30 sachets. J Child Adolesc Psychopharmacol. Zyprexa can also interact with other drugs, like diazepam and carbamazepine. How to Take Overdose Zyprexa (olanzapine) is an atypical antipsychotic medication used in the treatment of bipolar disorder, schizophrenia, and treatment-resistant depression. 2017;127(9):3402-3406. doi:10.1172/JCI93362. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Its promising for its ability to treat symptoms without the usual side effects of antipsychotic medications. Prices for olanzapine (Zyprexa) start at just $5.00 with a GoodRx coupon. Efficacy in schizophrenia was demonstrated in a dose range of 10 to 15 mg/day in clinical trials. Sildenafil (Viagra) and tadalafil (Cialis) are the most commonly prescribed medications for ED, and they have the longest track record. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Olanzapine (Zyprexa) can potentially cause seizures. Learn which medications might cause ED here. pharmacy with viagra. Make sure you know how this medication affects you before driving a car or doing activities that require your concentration. Dose Selection Oral olanzapine should be administered on a once-a-day schedule without regard to meals, generally beginning with 5 to 10 mg initially, with a target dose of 10 mg/day within several days. - We verify all health claims by cross-referencing them with the current scientific evidence. Zyprexa is used to treat psychotic conditions such as schizophrenia and bipolar disorder (manic depression) in adults and children at least 13 years old. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The U.S. Food and Drug Administration (FDA) has approved the oral form of Zyprexa for use in the treatment of: In some cases, Zyprexa is used as a standalone medication. Follow your physicians instructions carefully and never adjust dosage unless otherwise specified by your physician. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.BepridilBromoprideCisaprideDronedaroneLevomethadylMesoridazineMetoclopramidePimozidePiperaquineSaquinavirSparfloxacinTerfenadineThioridazineZiprasidoneUsing this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Consult with your healthcare provider if these side effects are bothersome to you or your child, or if they persist. 7 Key Facts About Atypical Antipsychotics You Should Know. If you have, Olanzapine (Zyprexa) can raise cholesterol (fat) levels in your blood and can cause weight gain. The safety of doses above 20 mg/day has not been evaluated in clinical trials [see Clinical Studies (14.2)]. A : If you are pregnant, lactating, have any medical condition or are taking medication, consult your physician. pharmacist if you have questions about the best way to throw out drugs. I'm just assuming that you are on it at 10 mg per day. For the dissolvable tablet (ODT), make sure your hands are dry before handling the medication. If you have questions, talk with Your doctor may decide not to treat you with this medication or change some of the other medicines you take. You will need to talk about the benefits and risks The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. It may take several weeks for a reduction in symptoms to be seen, so it's best to give the drug once a day. Our team conducts extensive research and analysis to ensure that our recommendations are reliable. It is response and effectiveness that are important. flushing, fast breathing, or breath that smells like fruit. Maximal dosing of intramuscular olanzapine (e.g., 3 doses of 10 mg administered 2-4 hours apart) may be associated with a substantial occurrence of significant orthostatic hypotension [see Warnings and Precautions (5.7)]. Olanzapine (Zyprexa) is an atypical antipsychotic that can help improve mood, thoughts, and behaviors for people with schizophrenia and bipolar disorder. National Alliance on Mental Health. It treats swelling from heart, kidney, or liver disease. Ask your provider if you've questions about taking olanzapine (Zyprexa) while breastfeeding. How long does it take for olanzapine (Zyprexa) to start to work? USD 3.90. Review the adverse event profile for olanzapine. Talk with your doctor before you use other drugs and natural products that slow your actions. Dosage adjustments, if indicated, should be made with the individual components according to efficacy and tolerability. Ask your provider if you've questions about the different atypical antipsychotics and their side effects. Symptoms of an overdose can include: If an overdose is suspected, call your medical provider or 911 immediately. Taking antipsychotic medications like olanzapine (Zyprexa) can cause uncontrolled body movements, such as eye-twitching or lip-smacking. It's not completely known how olanzapine (Zyprexa) works, but it's thought to work by balancing out the levels of chemicals (dopamine and serotonin) in your brain to help control your thoughts, mood, and behaviors. Safety and efficacy of ZYPREXA and fluoxetine in combination was determined in clinical trials supporting approval of Symbyax (fixed dose combination of ZYPREXA and fluoxetine). ZYPREXA IntraMuscular should not be combined in a syringe with haloperidol injection because the resulting low pH has been shown to degrade olanzapine over time. The feedback form on this page can be used to report content that is not accurate, up-to-date or questionable in any manner. In controlled clinical trials fixed-dose combination of Zyprexa and fluoxetine versus Symbyax yourself gets worse ), medication. Experience any of these symptoms while taking olanzapine ( Zyprexa ) can cause weight gain, metabolic disturbances cardiovascular. Six hours, peak blood levels can be reached if you 've questions about side effects latest evidence-based research should! Blood tests need to be performed regularly and physician visits should be made with the individual according... 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