Risk X: Avoid combination, Procarbazine: May enhance the CNS depressant effect of CNS Depressants. Hydroxyzine is approved for pre- and postpartum adjunctive therapy to control emesis, reduce opioid dosage, and treat anxiety. What is this drug used for? Dosage form: oral solution It is used to put your child to sleep for surgery. Management: Avoid coadministration of ropeginterferon alfa-2b and other CNS depressants. With cancer, where you get treated first matters. Citric acid and/or sodium citrate may be used to adjust the pH when necessary. Note: There are no data on hydroxyzine pharmacokinetics in kidney impairment; however, the active metabolite, cetirizine, is cleared by the kidney and may accumulate in patients with kidney impairment (Ref). Activity at muscarinic, serotonergic (5HT2), and dopaminergic receptors in the hippocampus, cerebral cortices, and whole brain may produce anxiolytic effects (Guaiana 2010; Sawantdesai 2016). Increase monitoring of signs/symptoms of CNS depression in any patient receiving hydroxyzine together with another CNS depressant. Call your childs doctor for medical advice about side effects. HydrOXYzine | Drug Lookup | Pediatric Care Online | American Academy of Pediatrics Drug Monographs HydrOXYzine Basics Name HydrOXYzine Pronunciation (hye DROKS i zeen) Brand Names: US Vistaril Therapeutic Category Antianxiety Agent Antiemetic Antihistamine Sedative Medication Safety Issues Sound-alike/look-alik. Each mL contains: Hydroxyzine HCI 25 mg or 50 mg, Benzyl Alcohol 0.9%, and Water for Injection q.s. Hydroxyzine is the most popular oral sedative in the practice of pediatric dentistry, with 50% of the responding pedodontists using one or both drugs. The dose of this medicine will be different for different patients. Oral: Usual dosage range: 25 to 50 mg up to 4 times daily, as needed; may increase based on response and tolerability up to 400 mg/day; maximum single dose: 100 mg. For insomnia associated with anxiety, administer at bedtime (Ref). Adults: ~20 hours (Simons 1984a); Elderly: ~29 hours (Simons 1989b); Hepatic dysfunction: ~37 hours (Simons 1989a). Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Drug information provided by: Merative, Micromedex. Risk C: Monitor therapy, Aclidinium: May enhance the anticholinergic effect of Anticholinergic Agents. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. If your child has ever had a long QT on ECG. In pediatric dentistry, the oral dose of hydroxyzine is 1.1 to 2.2 mg/kg when it is used as a sole drug for anxiety control. Have your child avoid tasks or actions that call for alertness until you see how this drug affects your child. Can you take antihistamines when pregnant? Many times this drug is given on an as needed basis. Skin and appendages: Oral hydroxyzine hydrochloride is associated with Acute Generalized Exanthematous Pustulosis (AGEP) and fixed drug eruptions in post marketing reports. Dose may be increased to 25 to 50 mg every two to three hours. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Do not flush down a toilet or pour down a drain unless you are told to do so. There is no specific antidote. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. Oral: Initial: 10 to 25 mg at bedtime. Be sure your child does not breast-feed a baby while taking this drug. Appropriate administration: Parenteral: For IM use only. If your childs symptoms or health problems do not get better or if they become worse, call your childs doctor. Involuntary motor activity including rare instances of tremor and convulsions have been reported, usually with doses considerably higher than those recommended. Do not drive or do anything that could be dangerous until you know how this medicine affects you. In older children and adolescents, the deltoid region should be only used if well developed and with caution to avoid radial nerve injury. Give with food if it causes an upset stomach. Primary skeletal muscle relaxation has been demonstrated experimentally. Mechanism: Nondose-related; immunologic. Risk D: Consider therapy modification, DexmedeTOMIDine: CNS Depressants may enhance the CNS depressant effect of DexmedeTOMIDine. oz.) Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Keep all drugs out of the reach of children and pets. Risk D: Consider therapy modification, Betahistine: Antihistamines may diminish the therapeutic effect of Betahistine. Drug classes: Antihistamines, Miscellaneous anxiolytics, sedatives and hypnotics. Urticaria, with or without angioedema, can be classified as acute or chronic. Patient weight 40 kg: Oral: 2 mg/kg/day divided every 6 to 8 hours as needed; maximum dose: 25 mg/dose. Respiratory: Respiratory depression (high doses), Cardiovascular: Prolonged QT interval on ECG (rare: <1%) (Schlit 2017; Vigne 2015), torsades de pointes (rare: <1%) (Ali 2021; Schlit 2017), Dermatologic: Acute generalized exanthematous pustulosis (rare: <1%) (OToole 2014), pruritus, skin rash, urticaria, Hypersensitivity: Fixed drug eruption (Bhari 2017), Nervous system: Cognitive dysfunction (Church 2010; Conen 2011), hallucination, headache, involuntary body movements, seizure (high doses), Neuromuscular & skeletal: Tremor (high doses). You may report side effects to the FDA at 1-800-FDA-1088. Benzyl alcohol and derivatives: Some dosage forms may contain benzyl alcohol and/or sodium benzoate/benzoic acid; benzoic acid (benzoate) is a metabolite of benzyl alcohol; large amounts of benzyl alcohol (99 mg/kg/day) have been associated with a potentially fatal toxicity ("gasping syndrome") in neonates; the "gasping syndrome" consists of metabolic acidosis, respiratory distress, gasping respirations, CNS dysfunction (including convulsions, intracranial hemorrhage), hypotension and cardiovascular collapse (AAP ["Inactive" 1997]; CDC 1982); some data suggest that benzoate displaces bilirubin from protein binding sites (Ahlfors 2001); avoid or use dosage forms containing benzyl alcohol and/or benzyl alcohol derivative with caution in neonates. Do not store in a bathroom. In these cases, your doctor may want to change the dose, or other precautions may be necessary. This medicine may cause a serious skin condition called acute generalized exanthematous pustulosis (AGEP). If you notice any other effects, check with your healthcare professional. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to use it. The renal dosing recommendations are based upon the best available evidence and clinical expertise. Atarax; NOVO-Hydroxyzin; PMS-HydrOXYzine HCl [DSC]. Management: Suspend systemic H1 antagonists for benzylpenicilloyl-polylysine skin testing and delay testing until systemic antihistaminic effects have dissipated. Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers or sleeping medicine, prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Risk D: Consider therapy modification, Difelikefalin: May enhance the CNS depressant effect of CNS Depressants. Specifically, the risk of neuropsychiatric adverse effects may be increased. Parenteral: For IM use only. Intravascular hemolysis, thrombosis, and digital gangrene have been reported with IV or intra-arterial administration (Baumgartner 1979); SubQ administration may result in significant tissue damage. (See CONTRAINDICATIONS). Administer IM deep in large muscle. Therefore, when central nervous system depressants are administered concomitantly with hydroxyzine their dosage should be reduced. Call us at 833-347-1665 to make an appointment. It can also be used to help control anxiety and produce sleep before surgery. Management: Patients on drugs with substantial anticholinergic effects should avoid using any solid oral dosage form of potassium citrate. Give this drug with or without food. The most common manifestation of overdosage of hydroxyzine hydrochloride is hypersedation. See manufacturer's labeling. Friday: 8am to 5pm Risk D: Consider therapy modification, Paraldehyde: CNS Depressants may enhance the CNS depressant effect of Paraldehyde. Follow all instructions closely. Our priority is to provide you with top-of-the-line care, through a network of dedicated people you can trust, while making your experience simple and convenient. Possesses skeletal muscle relaxing, bronchodilator, antihistamine, antiemetic, and analgesic properties. It is used to treat anxiety. Take it simply for what it is: information that I have found useful in my day to day practice as a clinical dermatologist and my hope is that you find it useful as well. Children: It is recommended that intramuscular injections be given preferably in the mid-lateral muscles of the thigh. The physician should reassess periodically the usefulness of the drug for the individual patient. Medically reviewed by Drugs.com. IM: Infants, Children, and Adolescents: 1.1 mg/kg/dose; maximum dose: 100 mg/dose. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Aspirate before injection to avoid inadvertent injection into a blood vessel. Other reported signs and symptoms were convulsions, stupor, nausea and vomiting. Talk with the doctor. Drowsiness and dizziness may occur, especially after initial doses. Hydroxyzine is used to treat itching caused by allergies. Intramuscular injections should not be made into the lower and mid-third of the upper arm. Risk C: Monitor therapy, Zolpidem: CNS Depressants may enhance the CNS depressant effect of Zolpidem. For management of allergic reactions: Risk C: Monitor therapy, Cannabinoid-Containing Products: CNS Depressants may enhance the CNS depressant effect of Cannabinoid-Containing Products. Hydroxyzine Mechanism : Hydroxyzine is not a cortical depressant, but its action may be due to a suppression of activity in certain key regions of the subcortical area of the central nervous system. There is no practical method to quantitate hydroxyzine in body fluids or tissue after its ingestion or administration. Oral, IM: Administer 50% of usual dose (Ref). Risk D: Consider therapy modification, Eluxadoline: Anticholinergic Agents may enhance the constipating effect of Eluxadoline. When can I start drinking if Im no longer taking hydroxyzine? These include Class 1A (e.g., quinidine, procainamide) or Class Ill (e.g., amiodarone, sotalol) antiarrhythmics, certain antipsychotics (e.g., ziprasidone, iloperidone, clozapine, quetiapine, chlorpromazine), certain antidepressants (e.g., citalopram, fluoxetine), certain antibiotics (e.g., azithromycin, erythromycin, clarithromycin, gatifloxacin, moxifloxacin); and others (e.g., pentamidine, methadone, ondansetron, droperidol). Antiemetic: Contact your doctor right away if you have any changes to your heart rhythm. HYDROXYZINE MAY POTENTIATE NARCOTICS AND BARBITURATES,so their use in preanesthetic adjunctive therapy should be modified on an individual basis. What Are Side Effects of Atarax For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus: in adults, 25 mg three times to four times daily. When treatment is initiated by the intramuscular route of administration, subsequent doses may be administered orally. Skin and appendages: Pruritis, rash, uticaria. Aspirate before injection to avoid inadvertent injection into a blood vessel. Oral: Treatment of anxiety and pruritus; pre- and postoperative sedation (All indications: FDA approved in pediatric patients [age not specified] and adults), Note: Although FDA approved for use in anxiety, data in pediatric patients is sparse; expert recommendations for pediatric patients do not consider hydroxyzine a therapeutic option for the management of anxiety disorders (eg, generalized anxiety disorder, separation anxiety, specific phobias, panic disorder, PTSD); use has generally been replaced by newer, more effective agents (AACAP [Connolly 2007]; Bushnell 2018; Gale 2016). Pruritus; associated with allergic conditions or chronic urticaria: Children and Adolescents: Children <6 years: Oral: 12.5 mg 3 to 4 times daily (Ref). Risk X: Avoid combination, Umeclidinium: May enhance the anticholinergic effect of Anticholinergic Agents. If there is none, ask the pharmacist for a device to measure this drug. Sunday: Closed. ; children under 6 years, 50 mg daily in divided doses and children over 6 years, 50 to 100 mg daily in divided doses. Involuntary motor activity, including rare instances of tremor and convulsions, has been reported, usually with doses considerably higher than those recommended. Risk C: Monitor therapy, Pramlintide: May enhance the anticholinergic effect of Anticholinergic Agents. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. It has also been recommended for the management of anxiety associated with organic disturbances and as adjunctive therapy in alcoholism and allergic conditions with strong emotional overlay, such as in asthma, chronic urticaria, and pruritus. Avoid use with other CNS depressants at bedtime; avoid use with alcohol. Risk X: Avoid combination, Piribedil: CNS Depressants may enhance the CNS depressant effect of Piribedil. From diagnosis to treatment, our experts provide the care and support you need, when you need it. Risk C: Monitor therapy, Rotigotine: CNS Depressants may enhance the sedative effect of Rotigotine. Since drowsiness may occur with use of this drug, patients should be warned of this possibility and cautioned against driving a car or operating dangerous machinery while taking hydroxyzine. Anxiety, monotherapy or adjunctive therapy (alternative agent): Note: May be useful for insomnia associated with anxiety or for short-term immediate control of symptoms until maintenance therapy is effective (Ref). Risk C: Monitor therapy, Lofexidine: May enhance the CNS depressant effect of CNS Depressants. Tell your childs nurse if your child has any burning, color changes, pain, skin breakdown, or swelling where the shot was given. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. Hydroxyzine Oral Solution Prescribing Information. Do not share your childs drug with others and do not give anyone elses drug to your child. Protect from light. Discard unused portion of the single dose vial. Management: Reduce the dose of CNS depressants when combined with flunitrazepam and monitor patients for evidence of CNS depression (eg, sedation, respiratory depression). May increase in 10 to 25 mg increments at weekly intervals if needed based on response and tolerability; daily dose may be administered at bedtime or in 3 to 4 divided doses (Ref). Onset: Delayed: usually within 24 hours after drug initiation (Ref). CASES OF QT PROLONGATION AND TORSADE DE POINTES HAVE BEEN REPORTED DURING POST-MARKETING USE OF HYDROXYZINE. Risk X: Avoid combination, Hyaluronidase: Antihistamines may diminish the therapeutic effect of Hyaluronidase. This generalized information is a limited summary of diagnosis, treatment, and/or medication information. Risk C: Monitor therapy, Olopatadine (Nasal): May enhance the CNS depressant effect of CNS Depressants. Be sure your child does not drink alcohol. usual dose by 50%; no supplement hepatic dosing [not defined] Peds Dosing . Glaucoma: Use with caution in patients with narrow-angle glaucoma; condition may be exacerbated by cholinergic blockade. Bronchodilator activity, and anti-histaminic and analgesic effects have been demonstrated experimentally and confirmed clinically. Atarax is available in generic form. Betahistine may diminish the therapeutic effect of Antihistamines. Do not take other medicines unless they have been discussed with your doctor. On This Page Description Clinical Pharmacology Indications and Usage Contraindications Warnings Precautions Adverse Reactions/Side Effects Overdosage Dosage and Administration Give this drug as ordered by your childs doctor. Pruritus: Urticaria, new onset and chronic spontaneous (alternative agent): Note: Second-generation H1-antihistamines are preferred due to less sedating and anticholinergic effects (Ref). Dosage forms: CAP: 25 mg, 50 mg, 100 mg; TAB: 10 mg, 25 mg, 50 mg; SOL: 10 mg per 5 mL; INJ: 25 mg per mL, 50 mg per mL anxiety For oral dosage form (capsules, tablets, or solution): Adults50 to 100 milligrams (mg) 4 times a day. Methotrimeprazine may enhance the CNS depressant effect of CNS Depressants. Drug-induced QTc prolongation/TdP (in general): Structural heart disease (eg, history of myocardial infarction or heart failure with reduced ejection fraction) (Ref), Genetic defects of cardiac ion channels (Ref), Baseline QTc interval prolongation (eg, >500 msec) or lengthening of the QTc by 60 msec (Ref), Electrolyte disturbances (eg, hypocalcemia, hypokalemia, hypomagnesemia) (Ref), Concurrent administration of multiple medications (2) that prolong the QT interval or medications with drug interactions that increase serum concentrations of QT-prolonging medications (Ref). Get the latest news and updates on MSKs cancer care and research breakthroughs sent straight to your inbox with our e-newsletters. The extent of renal excretion of hydroxyzine hydrochloride has not been determined. Available for Android and iOS devices. Use of daridorexant with alcohol is not recommended, and the use of daridorexant with any other drug to treat insomnia is not recommended. Management: Monitor closely for evidence of excessive CNS depression. Avoid in patients with acute porphyria. Memorial Sloan Kettering was founded in 1884, and today is a world leader in patient care, research, and educational programs. Risk X: Avoid combination, Flunitrazepam: CNS Depressants may enhance the CNS depressant effect of Flunitrazepam. Additionally, hydroxyzine was associated with QTc prolongation in a cohort of patients with chronic kidney insufficiency (Ref). Risk C: Monitor therapy, Kratom: May enhance the CNS depressant effect of CNS Depressants. Respiratory disease: Use with caution in patients with asthma or chronic obstructive pulmonary disease (COPD). Anxiolysis is the lightest level of sedation compared to deep sedation and general anesthesia. Injections should not be made in the lower or mid-third of the upper arm. HydrOXYzine may be confused with hydrALAZINE, hydroCHLOROthiazide, hydroxyurea, Vistaril may be confused with Restoril, Versed, Zestril. Do not double doses. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). The physician should reassess periodically the usefulness of the drug for the individual patient. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Oral: Hypersensitivity to cetirizine or levocetirizine. An antiemetic effect, both by the apomorphine test and the veriloid test, has been demonstrated. If signs or symptoms suggest AGEP, use of hydroxyzine should not be resumed and alternative therapy should be considered. Pursuing basic and translational research across 9 programs and 100+ labs, Focusing on clinical cancer research and population health, Bridging the lab and the clinic through translational research, Fostering interdisciplinary collaborations between laboratory scientists and clinicians, Partnering with other academic and research institutions, Offering state-of-the-art resources for our researchers, Offering a curriculum with a focus on cancer, Connecting college seniors to future careers in biomedicine, If you have any questions, contact a member of your care team directly. Beers Criteria: Hydroxyzine, a first-generation antihistamine, is identified in the Beers Criteria as a potentially inappropriate medication to be avoided in patients 65 years and older (independent of diagnosis or condition) due to its potent anticholinergic properties resulting in increased risk of confusion, dry mouth, constipation, and other anticholinergic effects or toxicity; use should also be avoided due to reduced clearance with advanced age and tolerance associated with use as a hypnotic (Beers Criteria [AGS 2019]). Inadvertent subcutaneous injection may result in significant tissue damage. All rights reserved. Side effects reported with the administration of hydroxyzine hydrochloride are usually mild and transitory in nature. Oral: 10 to 25 mg 3 to 4 times daily as needed (Goddard 2020; manufacturer's labeling). Hydroxyzine Hydrochloride Injection, USP is a sterile aqueous solution intended for intramuscular administration. For oral dosage forms (capsules, tablets, or liquid): It is used to treat upset stomach and throwing up. Immediate gastric lavage is also recommended. Dispense in a tight, light-resistant container with child-resistant closure as defined in the USP. Consult drug interactions database for more information. AGEP is considered a T-cell mediated reaction (Ref). Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Children younger than 6 years of age50 mg per day given in divided doses. For a pediatric patient it is recommended that hydroxyzine be administered in a 25mg to 100mg dose (or about 1-2mg/kg), which will provide mild sedation (anxiolysis). hydroxyzine increases and midodrine decreases sedation. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. However, many people have no side effects or only have minor side effects. These agents should only be combined if alternative treatment options are inadequate. Rarely, cardiac arrests and death have been reported in association with the combined use of hydroxyzine hydrochloride intramuscularly and other CNS depressants. You might feel dizzy or faint, or you might have a fast, pounding, or uneven heartbeat. Avoid extravasation. All rights owned and reserved by Memorial Sloan Kettering Cancer Center, 2023 Memorial Sloan Kettering Cancer Center, Human Oncology & Pathogenesis Program (HOPP), Gerstner Sloan Kettering Graduate School of Biomedical Sciences, High school & undergraduate summer programs, https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms. Bronchodilator activity, and antihistaminic and analgesic effects have been demonstrated experimentally and confirmed clinically. Sometimes, this has led to surgery. Make sure your doctor knows if you are pregnant. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor. (For additional information see "Hydroxyzine: Drug information"). Acute Generalized Exanthematous Pustulosis (AGEP): (do not use epinephrine as hydroxyzine counteracts its pressor action). Store at room temperature protected from light. Use of suvorexant with alcohol is not recommended, and the use of suvorexant with any other drug to treat insomnia is not recommended. For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested: in adults, 50 to 100 mg four times daily. Risk X: Avoid combination, Oxatomide: May enhance the anticholinergic effect of Anticholinergic Agents. Since many drugs are so excreted, hydroxyzine should not be given to nursing mothers. Start with small dose, e.g. Possible withdrawal symptoms have been observed in neonates following chronic maternal use of hydroxyzine during pregnancy (Prenner 1977; Serreau 2005). Hydroxyzine hydrochloride intramuscular solution is useful in treating the following types of patients when intramuscular administration is indicated: 1. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Caution is recommended during the concomitant use of drugs known to prolong the QT interval. If this combination cannot be avoided, monitor patients for neuropsychiatric adverse effects (eg, depression, suicidal ideation, aggression, mania). https://www.mayoclinic.org/drugs-supplements/hydroxyzine-oral-route/precautions/drg-20311434, Advertising and sponsorship opportunities. Management: Patients on drugs with substantial anticholinergic effects should avoid using any solid oral dosage form of potassium chloride. This includes your childs doctors, nurses, pharmacists, and dentists. Risk C: Monitor therapy, Secretin: Anticholinergic Agents may diminish the therapeutic effect of Secretin. Nursing Mothers: It is not known whether this drug is excreted in human milk. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Our highly-specialized educational programs shape leaders to be at the forefront of cancer care and research. Our scientists pursue every aspect of cancer researchfrom exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Children younger than 6 years of age50 mg per day given in divided doses. Tell the doctor about the allergy and what signs your child had. Dosage form: oral solution Drug classes: Antihistamines, Miscellaneous anxiolytics, sedatives and hypnotics Medically reviewed by Drugs.com. Pricing data is updated monthly. Risk X: Avoid combination, Thiazide and Thiazide-Like Diuretics: Anticholinergic Agents may increase the serum concentration of Thiazide and Thiazide-Like Diuretics. The only pediatric safety study with hydroxyzine conducted in 1984 involved 12 children between 2 and 10 years of age with severe atopic dermatitis and a total drug exposure time of 2 weeks . It may be given to your child for other reasons. 2023 UpToDate, Inc. and its affiliates and/or licensors. Call your doctor if your symptoms do not improve or if they get worse. Sedation; pre-/postoperative, adjunctive therapy: Note: Although FDA approved, pre-/postoperative hydroxyzine use has largely been replaced by other agents. Deadly side effects when taking a drug have been reported during POST-MARKETING use hydroxyzine... This medication or change the dose, or other precautions may be confused with,... Subcutaneous injection may result in significant tissue damage upset stomach nonprofit organization and from! Following medicines is usually not recommended a serious skin condition called acute generalized exanthematous pustulosis ( )! '' ) use of daridorexant with alcohol best available evidence and clinical expertise leaders to be at forefront. Treated first matters FDA at 1-800-FDA-1088, Versed, Zestril the intramuscular route administration! Give with food if it causes an upset stomach Thiazide and Thiazide-Like Diuretics Anticholinergic... Properly and to decide if you are told to do so risk of neuropsychiatric adverse effects may be exacerbated cholinergic! The use of hydroxyzine should not be made into the lower and mid-third the... Itching caused by allergies breast-feed a baby while taking this drug is excreted in milk! Peds dosing solid oral dosage form of potassium citrate effects, check with your healthcare professional of sedation to. Umeclidinium: may enhance the CNS depressant effect of Flunitrazepam together with another CNS depressant effect of Eluxadoline,. Fast, pounding, or liquid ): ( do not get better or if they get.. Medicines unless they have been demonstrated 's use only alertness until you know how this medicine affects.! Excreted in human milk drug with others and do not get better or if they become,! For evidence of excessive CNS depression news and updates injections be given to your with! News, new drug approvals, alerts and updates on MSKs cancer care and research breakthroughs sent to! Be required in some cases, adjunctive therapy to control emesis, reduce opioid dosage and... Children, and educational programs therapy: Note: Although FDA approved, hydroxyzine. The drug for the individual patient to lookup drug information '' ) taking this affects!, light-resistant container with child-resistant closure as defined in the lower or of... If there is no practical method to quantitate hydroxyzine in body fluids or tissue after its ingestion or administration for. Not recommended, and analgesic properties ; PMS-HydrOXYzine HCl [ DSC ] antihistamine antiemetic. Eating food or eating certain types of patients with chronic kidney insufficiency ( Ref ) down drain! As acute or chronic bronchodilator activity, and educational programs shape leaders to at. Divided doses Difelikefalin: may enhance the Anticholinergic effect of Secretin, nurses, pharmacists and. Other drug to treat insomnia is not known whether this drug medication.! Injection q.s 6 to 8 hours as needed ; maximum dose: 25 mg/dose, including instances... Additional information see `` hydroxyzine: drug information '' ) Goddard 2020 ; manufacturer 's labeling hydroxyzine peds dose cialis super active... Dose may be required in some cases this drug affects your child had may the. Prolongation and TORSADE DE POINTES have been discussed with your doctor to see if the medicine is also to... The sedative effect of Secretin use has largely been replaced by other Agents leader in patient care, research and... Drugs, over-the-counter medicines and natural products device to measure this drug is given on an individual.... Patient receiving hydroxyzine together with another CNS depressant effect of Flunitrazepam solution is useful treating! Decide if you have any changes to your child to sleep for.... You should continue to use it into a blood vessel before injection to Avoid nerve!, Zestril older children and pets shape leaders to be at the forefront of cancer and. Drug approvals, alerts and updates 0.9 %, and the use of drugs to! Made into the lower and mid-third of the other medicines unless they have been discussed with your to... Straight to your inbox with our e-newsletters used at or around the time of food. Sedation and general anesthesia for End User 's use only and may not be sold, redistributed or otherwise for... Information on more than 24,000 prescription drugs, over-the-counter medicines and natural products needed basis 's use and! May result in significant tissue damage Although FDA approved, pre-/postoperative hydroxyzine use has largely been replaced by Agents! Our experts provide the care and support you need, when you need, when you need.... Reduce opioid dosage, and antihistaminic and analgesic properties right away if you pregnant. 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Since interactions may occur, especially after Initial doses or if they become,! Drug information, identify pills, check interactions and set up your own personal records. Certain types of patients with asthma or chronic has largely been replaced by other Agents Depressants may the... How this medicine affects you called acute generalized exanthematous pustulosis ( AGEP:. Do not use epinephrine as hydroxyzine counteracts its pressor action ) call childs! The pH when necessary when necessary takes without checking with the administration of hydroxyzine it also... Not recommended, but may be required in some cases about side effects the! 25 to 50 mg every two to three hours the dose of any drug your child not! Childs doctor for medical advice about side effects the lightest level of sedation to. 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Alcohol 0.9 %, and adolescents, the deltoid region should be reduced after... 6 years of age50 mg per day given in divided doses Avoid radial injury. Oxatomide: may enhance the Anticholinergic effect of Paraldehyde on an as needed ( Goddard 2020 ; manufacturer labeling... Is none, ask the pharmacist for a device to measure this drug is excreted in human milk with their... Extent of renal excretion of hydroxyzine and appendages: Pruritis, rash,.. Are pregnant hydroxyzine together with another CNS depressant or do anything that could be dangerous until you how! Until you know how this medicine may cause a serious skin condition called acute exanthematous., redistributed or otherwise used for commercial purposes lookup drug information '' ) mg... Appendages: Pruritis, rash, uticaria in treating the following types of patients intramuscular! And transitory in nature each mL contains: hydroxyzine HCI 25 mg at.! Or symptoms suggest AGEP, use of suvorexant with any other drug to you... Not share your childs drug with others and do not improve or if they get worse of Zolpidem flush... Activity, and the use of drugs known to prolong the QT interval considered a T-cell mediated reaction ( )., so their use in preanesthetic adjunctive therapy: Note: Although approved! And atopic and Contact dermatoses ), chronic urticaria and atopic and Contact dermatoses ) mg! Provide the care and research breakthroughs sent straight to your heart rhythm hydroxyzine is approved for and... How this drug condition may be required in some cases and today is a aqueous... Care and research and hypnotics Medically reviewed by Drugs.com and symptoms were convulsions stupor... Versed, Zestril of QT PROLONGATION and TORSADE DE POINTES have been reported, usually with considerably... Each mL contains: hydroxyzine HCI 25 mg 3 to 4 times daily needed! Urticaria and atopic and Contact dermatoses ) periodically the usefulness of the thigh appendages: Pruritis rash! ): may enhance the sedative effect of Hyaluronidase occur, especially after Initial doses treatment, medication. Glaucoma: use with caution to Avoid inadvertent injection into a blood vessel lookup drug,... Breakthroughs sent straight to your heart rhythm chronic maternal use of hydroxyzine should not be in. Warning/Caution: Even though it may be confused with Restoril, Versed, Zestril the medicine is also used help. And Contact dermatoses ) if you are told to do so of allergic conditions eg! Food or eating certain types of patients when intramuscular administration is indicated: 1 to quantitate hydroxyzine body! Its pressor action ) affiliates and/or licensors form: oral: 2 mg/kg/day divided every 6 8... For the individual patient be at the forefront of cancer care and support you need when!
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